Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Moloud Ahmadi"'
Autor:
Graham MacLeod, Danielle A. Bozek, Nishani Rajakulendran, Vernon Monteiro, Moloud Ahmadi, Zachary Steinhart, Michelle M. Kushida, Helen Yu, Fiona J. Coutinho, Florence M.G. Cavalli, Ian Restall, Xiaoguang Hao, Traver Hart, H. Artee Luchman, Samuel Weiss, Peter B. Dirks, Stephane Angers
Publikováno v:
Cell Reports, Vol 27, Iss 3, Pp 971-986.e9 (2019)
Summary: Glioblastoma therapies have remained elusive due to limitations in understanding mechanisms of growth and survival of the tumorigenic population. Using CRISPR-Cas9 approaches in patient-derived GBM stem cells (GSCs) to interrogate function o
Externí odkaz:
https://doaj.org/article/0511f6979a6e4ca6a822f0c9bbbca14e
Autor:
Moloud Ahmadi, Richard Roy
Publikováno v:
eLife, Vol 5 (2016)
The stress associated with starvation is accompanied by compensatory behaviours that enhance foraging efficiency and increase the probability of encountering food. However, the molecular details of how hunger triggers changes in the activity of neura
Externí odkaz:
https://doaj.org/article/85434c86cf1a4b66ad0e812914332ca1
Autor:
Moloud Ahmadi, Nafise Nili, Shaghayegh Haghjooy Javanmard, Hajar Naji, Ebrahim Sayed Tabatabaei
Publikováno v:
مجله دانشکده پزشکی اصفهان, Vol 30, Iss 194 (2012)
Background: Inhibition of endothelial dysfunction and denudation contributes to the attenuation of atherosclerosis. Numerous studies have suggested that nutritional antioxidants can contribute to the reduction of atherosclerotic lesions. The goals of
Externí odkaz:
https://doaj.org/article/43e32185f13d40c6a08090ce1c28586e
Autor:
Mathieu Lupien, Naghmeh Rastegar, Erika Luis, Peter B. Dirks, Danielle Bozek, Richard A. Moore, Naijin Li, Owen K. N. Whitley, Fiona J. Coutinho, Marco A. Marra, Clare Che, Paul Guilhamon, H. Artee Luchman, Florence M.G. Cavalli, Mazdak Riverin, Lilian Lee, Nicole I. Park, Trevor J. Pugh, Benjamin Haibe-Kains, Michael D. Cusimano, Stephane Angers, Graham MacLeod, Gary D. Bader, Mark Bernstein, Julia E. Jaramillo, Julian Spears, Nataliia Svergun, Samuel Weiss, Sunit Das, Moloud Ahmadi, Danielle C Croucher, Troy Ketela, Michelle Kushida, Kenny Yu, Jasmine K. Bhatti, Zhiyu Xu, Laura M. Richards
Publikováno v:
Nature Cancer. 2:157-173
Glioblastomas harbor diverse cell populations, including rare glioblastoma stem cells (GSCs) that drive tumorigenesis. To characterize functional diversity within this population, we performed single-cell RNA sequencing on >69,000 GSCs cultured from
Autor:
Jagotamoy Das, Haijie Chen, Fan Xia, Zongjie Wang, Sharif Uddin Ahmed, Shana O. Kelley, Moloud Ahmadi, Edward H. Sargent, Stephane Angers, Mahmoud Labib
Publikováno v:
ACS Nano. 14:5324-5336
Dynamic modulation of cellular phenotypes between the epithelial and mesenchymal states-the epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET)-plays an important role in cancer progression. Nanoscale topography of cul
Autor:
Nishani Rajakulendran, Molaei F, Zachary Steinhart, Stephane Angers, Nicole I. Park, Moloud Ahmadi, Milena Kosic, Gregory T. Macleod, Sichun Lin, Peter B. Dirks, Andy Yang
Glioblastoma stem cells (GSCs) exhibit latent neuronal lineage differentiation potential governed by the proneural transcription factor Achaete-scute homolog 1 (ASCL1) and harnessing and promoting terminal neuronal differentiation has been proposed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccb456eacdde2c28b0d18c4bd8ae86eb
https://doi.org/10.1101/2021.05.04.442579
https://doi.org/10.1101/2021.05.04.442579
Autor:
Samuel Weiss, Leo J.Y. Kim, Xiaochong Wu, Randy Van Ommeren, Yanqing Jiang, Kaitlin Kharas, Evgeny Kanshin, Moloud Ahmadi, Alberto Delaidelli, Geneviève Deblois, David Przelicki, Stephane Angers, Hiromichi Suzuki, Sameer Agnihotri, Bradly G. Wouters, Graham MacLeod, Ricky Tsai, Pasqualino De Antonellis, Michelle Ly, Stacey L. Krumholtz, Paul Guilhamon, James Loukides, Ravi N. Vellanki, Alex Rasnitsyn, Hamza Farooq, Daniel Schramek, Nada Jabado, María Sánchez-Osuna, Laura K. Donovan, Vijay Ramaswamy, Ibrahim El-Hamamy, Joonas Haapasalo, Jeremy N. Rich, Michael D. Taylor, Benjamin A. Garcia, Mike Tyers, Kyle Juraschka, Winnie Ong, Olivier Saulnier, Panagiotis Prinos, John J.Y. Lee, Borja L. Holgado, Olga Sirbu, Craig Daniels, Cheryl H. Arrowsmith, Cory Richman, Poul H. Sorensen, Kulandaimanuvel Antony Michealraj, Sheila K. Singh, Andrea Bajic, Polina Balin, Stephen C. Mack, Betty Luu, Fiona J. Coutinho, Dilakshan Srikanthan, Florence M.G. Cavalli, Sachin Kumar, Evan Y. Wang, Mathieu Lupien, Peter B. Dirks, Maria C. Vladoiu, Lincoln Stein, Livia Garzia, Ahmad Malik, John Wojcik, Avesta Rastan
Posterior fossa A (PFA) ependymomas are lethal malignancies of the hindbrain in infants and toddlers. Lacking highly recurrent somatic mutations, PFA ependymomas are proposed to be epigenetically driven tumors for which model systems are lacking. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4cbadadef8c1b79cfc6c9ec6f333d8
https://hdl.handle.net/11588/900834
https://hdl.handle.net/11588/900834
Autor:
Libing Zhang, Mahla Poudineh, Stephane Angers, Shana O. Kelley, Moloud Ahmadi, Jagotamoy Das, Mahmoud Labib, Sharif Uddin Ahmed, Zongjie Wang
Publikováno v:
Nano Letters. 18:7188-7193
Cell morphology and geometry affect cellular processes such as stem cell differentiation, suggesting that these parameters serve as fundamental regulators of biological processes within the cell. Hierarchical architectures featuring micro- and nanoto
Autor:
Peter B. Dirks, Samuel Weiss, Nishani Rajakulendran, Stephane Angers, Moloud Ahmadi, Artee Luchman, Danielle Bozek, Graham MacLeod
Publikováno v:
Neuro Oncol
Advances in the characterization of the genetic, epigenetic and transcriptomic landscapes of glioblastoma (GBM) tumor samples and primary cell lines have yielded considerable insight into tumor initiation and progression. A major finding from these s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01cfc2683429611b29fce6637e73782e
https://europepmc.org/articles/PMC6847826/
https://europepmc.org/articles/PMC6847826/
Autor:
Graham MacLeod, Moloud Ahmadi, Samuel Weiss, Nishani Rajakulendran, Stephane Angers, Xiaoguang Hao, Artee Luchman, Danielle Bozek, Peter B. Dirks
Publikováno v:
Neuro Oncol
Glioblastoma (GBM), the most common and aggressive primary adult brain cancer, is thought to be driven by a small subpopulation of brain tumor stem cells (BTSCs). BTSCs exhibit shared properties with normal stem cells such as self-renewal and multili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7a51b9d99c1c9c3bc7d74bfd4c8b5d
https://europepmc.org/articles/PMC6847418/
https://europepmc.org/articles/PMC6847418/