Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Moloney Murine Leukemia Virus TB"'
Publikováno v:
Journal of Virology. 67:1137-1147
ts1 is a highly neuropathogenic and lymphocytopathic mutant of Moloney murine leukemia virus TB (MoMuLV-TB). We previously reported that the primary neuropathogenic determinant of ts1 maps to a single amino acid substitution, Val-25-->Ile, in precurs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7c4ed209a87a8ff4291277b53b4c8e
https://doi.org/10.1128/jvi.67.3.1137-1147.1993
https://doi.org/10.1128/jvi.67.3.1137-1147.1993
Publikováno v:
Virology. 184:687-694
Ts 1, a temperature-sensitive mutant of Moloney murine leukemia virus-TB (MoMuLV-TB), causes a progressive hindlimb paralytic disease in susceptible strains of mice. Previously, it has been shown that a single amino acid substitution, Val-25→Ile in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c3b2b0cd4f03297810b0948f3e02cf6
https://doi.org/10.1016/0042-6822(91)90438-h
https://doi.org/10.1016/0042-6822(91)90438-h
Publikováno v:
Virology. 180:365-371
The ts1 mutant of Moloney murine leukemia virus TB causes a degenerative neurologic and immunologic disease in susceptible strains of mice. This disease syndrome is characterized by development of spongiform encephalomyelopathy resulting in hindlimb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c49fdcc0df78e7e8d503df44ad7a9d1
https://doi.org/10.1016/0042-6822(91)90041-9
https://doi.org/10.1016/0042-6822(91)90041-9
Publikováno v:
Journal of Virology. 64:5241-5249
ts1, a spontaneous temperature-sensitive mutant of Moloney murine leukemia virus TB, causes hind-limb paralysis in mice. A Val-25----Ile substitution in gPr80env is responsible for temperature sensitivity, inefficient processing of gPr80env, and neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eeaff229975ac0f46a2d095886e178d
https://doi.org/10.1128/jvi.64.11.5241-5249.1990
https://doi.org/10.1128/jvi.64.11.5241-5249.1990
Publikováno v:
Journal of Virology. 64:467-475
ts1 is a neurovirulent spontaneous temperature-sensitive mutant of Moloney murine leukemia virus TB which causes hindlimb paralysis in mice. Previously, it had been shown that the temperature-sensitive defect resided in the env gene. At the restricti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38bc7d44974bd159037495193d6d0711
https://doi.org/10.1128/jvi.64.2.467-475.1990
https://doi.org/10.1128/jvi.64.2.467-475.1990
Autor:
Paul K.Y. Wong, Kunal Saha
When neonatal FVB/N mice were inoculated with ts1, a temperature-sensitive mutant of Moloney murine leukemia virus TB, they developed a progressive bilateral hindlimb paralysis and immunodeficiency leading to death 4 to 6 weeks after inoculation. T l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297679c723acfd569dfac2b062727052
https://europepmc.org/articles/PMC241017/
https://europepmc.org/articles/PMC241017/
The ts1 mutant of Moloney murine leukemia virus TB causes degenerative neurologic and immunologic disease in mice, characterized by development of spongiform encephalomyelopathy resulting in hindlimb paralysis, marked thymic atrophy associated with i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03230a14f3c1d14a8a9fa0d8a3233e4
https://europepmc.org/articles/PMC52637/
https://europepmc.org/articles/PMC52637/
Autor:
Kunal Saha, Paul K.Y. Wong
Publikováno v:
Virology. 183(2)
BALB/c mice when injected as newborn with ts1, a temperature-sensitive mutant of Moloney murine leukemia virus-TB, developed a fatal hindlimb paralysis and immunodeficiency. This disease induction was prevented, to a great extent, by transient deplet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6348cb29f49116fdec3a9326229d9e56
https://pubmed.ncbi.nlm.nih.gov/1853579
https://pubmed.ncbi.nlm.nih.gov/1853579
Publikováno v:
Virology. 169:332-340
Newborn homozygous BALB/c nude (nu/nu) mice, their heterozygous (+/nu) littermates, and normal BALB/c (+/+) mice were infected with ts1, a paralytogenic mutant of Moloney murine leukemia virus-TB (MoMuLV-TB). Our results indicate that while infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b063ac6b4cdc1fa4979f64458858cc
https://doi.org/10.1016/0042-6822(89)90158-x
https://doi.org/10.1016/0042-6822(89)90158-x
Publikováno v:
Journal of Virology. 54:178-185
ts1 and ts7, the paralytogenic, temperature-sensitive mutants of Moloney murine leukemia virus (MoMuLV), together with their wild-type parent, MoMuLV-TB, were molecularly cloned. ts1-19, ts7-22, and wt-25, the infectious viruses obtained on transfect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ad1a916fd89200aeceb023bb55f95f
https://doi.org/10.1128/jvi.54.1.178-185.1985
https://doi.org/10.1128/jvi.54.1.178-185.1985