Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Molly V. Campbell"'
Autor:
Molly V. Campbell, Christopher J. Savich, Tyler J. Wall, Haven A. Barna, Christina L. Magyar, R. Adam Mosey, Steven B. Davies, Sydney R. Smith
Publikováno v:
Org Biomol Chem
A one-pot three-component tandem reaction involving a key Pictet-Spengler-like annulation step has been developed, providing an efficient method for the synthesis of 3,4-dihydroquinazolines in moderate to good yields from amides, aldehydes, and amine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb17167b83270f0f81a26d0c31edf08
https://doi.org/10.1039/c9ob01596e
https://doi.org/10.1039/c9ob01596e
Autor:
Steven B. Davies, Tyler J. Wall, Christopher J. Savich, Jetze J. Tepe, Taylor J. Fiolek, Molly V. Campbell, Christina L. Magyar, R. Adam Mosey
Publikováno v:
Bioorg Med Chem Lett
Aggregates or oligomeric forms of many intrinsically disordered proteins (IDPs), including α-synuclein, are hallmarks of neurodegenerative diseases, like Parkinson's and Alzheimer's disease, and key contributors to their pathogenesis. Due to their d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5408e1c22d23af94dd1c87b24774e7
https://pubmed.ncbi.nlm.nih.gov/33513387
https://pubmed.ncbi.nlm.nih.gov/33513387
Publikováno v:
The Journal of organic chemistry. 85(17)
A multicomponent tandem assembly procedure for the synthesis of diverse C4-quaternary 3,4-dihydroquinazolines from amides, amines, and ketones has been developed. The one-pot reaction involves successive triflic anhydride mediated amide dehydration,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb9744a93d019883771d031f7bdd3d4
https://pubmed.ncbi.nlm.nih.gov/32786625
https://pubmed.ncbi.nlm.nih.gov/32786625