Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Molly T. McDevitt"'
Autor:
Karen Rosier, Molly T. McDevitt, Joél Smet, Brendan J. Floyd, Maxime Verschoore, Maria J. Marcaida, Craig A. Bingman, Irma Lemmens, Matteo Dal Peraro, Jan Tavernier, Benjamin F. Cravatt, Natalia V. Gounko, Katlijn Vints, Yenthe Monnens, Kritika Bhalla, Laetitia Aerts, Edrees H. Rashan, Arnaud V. Vanlander, Rudy Van Coster, Luc Régal, David J. Pagliarini, John W.M. Creemers
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103460- (2021)
Summary: Deficiency of the serine hydrolase prolyl endopeptidase-like (PREPL) causes a recessive metabolic disorder characterized by neonatal hypotonia, feeding difficulties, and growth hormone deficiency. The pathophysiology of PREPL deficiency and
Externí odkaz:
https://doaj.org/article/a2916c2ecc194c18bb66fc5774a5e60f
Autor:
David J. Pagliarini, Kritika Bhalla, Karen Rosier, Brendan J. Floyd, Rudy Van Coster, John W.M. Creemers, Irma Lemmens, Edrees H. Rashan, Maxime Verschoore, Benjamin F. Cravatt, Matteo Dal Peraro, Katlijn Vints, Luc Régal, Joél Smet, Laetitia Aerts, Arnaud Vanlander, Yenthe Monnens, Natalia V. Gounko, Craig A. Bingman, Jan Tavernier, Molly T. McDevitt, Maria J. Marcaida
Publikováno v:
iScience
ISCIENCE
iScience, Vol 24, Iss 12, Pp 103460-(2021)
ISCIENCE
iScience, Vol 24, Iss 12, Pp 103460-(2021)
Summary Deficiency of the serine hydrolase prolyl endopeptidase-like (PREPL) causes a recessive metabolic disorder characterized by neonatal hypotonia, feeding difficulties, and growth hormone deficiency. The pathophysiology of PREPL deficiency and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d632ef57ff0933bdaa806f554927a20
https://hdl.handle.net/20.500.14017/c7bfdaf7-1b1c-4a72-9f07-6f40a36a6606
https://hdl.handle.net/20.500.14017/c7bfdaf7-1b1c-4a72-9f07-6f40a36a6606
Autor:
Stefely, Joshua J. Coon, Erin Weisenhorn, R.W. Smith, Danielle C. Lohman, Adam Jochem, Craig A. Bingman, Vanessa Linke, B. Wancewicz, Jason D. Russell, Emily T. Beebe, David J. Pagliarini, Molly T. McDevitt, Deniz Aydin, M. Dal Peraro, Emily M. Wilkerson, Paul D. Hutchins, H.C. Von Bank
Publikováno v:
Molecular cell. 73(4)
The biosynthesis of coenzyme Q presents a paradigm for how cells surmount hydrophobic barriers in lipid biology. In eukaryotes, CoQ precursors—among nature’s most hydrophobic molecules—must somehow be presented to a series of enzymes peripheral
Autor:
Arne Ulbrich, Johan Auwerx, Maroun Bou Sleiman, Molly T. McDevitt, David J. Pagliarini, Joshua J. Coon, Karim Gariani, Pooja Jha, Evan G. Williams, Emina Halilbasic, Rahul Gupta, Michael Trauner, Pedro M. Quirós, Adam Jochem
Publikováno v:
Cell Systems, 6 (6)
Cell systems
Cell Systems, Vol. 6, No 6 (2018) pp. 709-721.e6
Cell systems
Cell Systems, Vol. 6, No 6 (2018) pp. 709-721.e6
SUMMARY The genetic regulation and physiological impact of most lipid species are unexplored. Here, we profiled 129 plasma lipid species across 49 strains of the BXD mouse genetic reference population fed either chow or a high-fat diet. By integratin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5465682eeeed0da6af64e19c59c68629
Autor:
Matteo Dal Peraro, Craig A. Bingman, Emily M. Wilkerson, Paul D. Hutchins, Jonathan A. Stefely, Adam Jochem, David J. Pagliarini, Joshua J. Coon, Jaime L. Stark, John L. Markley, Molly T. McDevitt, Deniz Aydin, Zachary A. Kemmerer, Isabel E. Johnson, Andrew G. Reidenbach
SummaryHuman COQ8A (ADCK3) andSaccharomyces cerevisiaeCoq8p (collectively COQ8) are UbiB family proteins essential for mitochondrial coenzyme Q (CoQ) biosynthesis. However, the biochemical activity of COQ8 and its direct role in CoQ production remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b99fe30a1c8355906e4baee654bc30
https://doi.org/10.1101/149823
https://doi.org/10.1101/149823
Autor:
Derek J. Bailey, David J. Pagliarini, Michael S. Westphall, Molly T. McDevitt, Joshua J. Coon
Publikováno v:
Journal of Proteome Research
A mass spectrometry (MS) method is described here that can reproducibly identify hundreds of peptides across multiple experiments. The method uses intelligent data acquisition to precisely target peptides while simultaneously identifying thousands of
Autor:
Paul D. Hutchins, Adam Jochem, Joshua J. Coon, Thiru R. Reddy, Matteo Dal Peraro, Craig A. Bingman, Emily M. Wilkerson, Alexander S. Hebert, Jonathan A. Stefely, Molly T. McDevitt, Deniz Aydin, Zachary A. Kemmerer, Andrew G. Reidenbach, Jaime L. Stark, Isabel E. Johnson, John L. Markley, David J. Pagliarini
Publikováno v:
Cell Chemical Biology. 25:154-165.e11
Human COQ8A (ADCK3) and Saccharomyces cerevisiae Coq8p (collectively COQ8) are UbiB family proteins essential for mitochondrial coenzyme Q (CoQ) biosynthesis. However, the biochemical activity of COQ8 and its direct role in CoQ production remain uncl