Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Molly Smullen"'
Autor:
Molly Smullen, Meagan N. Olson, Liam F. Murray, Madhusoodhanan Suresh, Guang Yan, Pepper Dawes, Nathaniel J. Barton, Jivanna N. Mason, Yucheng Zhang, Aria A. Fernandez-Fontaine, George M. Church, Diego Mastroeni, Qi Wang, Elaine T. Lim, Yingleong Chan, Benjamin Readhead
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Mitochondrial (MT) dysfunction has been associated with several neurodegenerative diseases including Alzheimer’s disease (AD). While MT-copy number differences have been implicated in AD, the effect of MT heteroplasmy on AD has not been we
Externí odkaz:
https://doaj.org/article/7f133d69551245a7bf77cd609ed77e08
Autor:
Pepper Dawes, Liam F. Murray, Meagan N. Olson, Nathaniel J. Barton, Molly Smullen, Madhusoodhanan Suresh, Guang Yan, Yucheng Zhang, Aria Fernandez-Fontaine, Jay English, Mohammed Uddin, ChangHui Pak, George M. Church, Yingleong Chan, Elaine T. Lim
Publikováno v:
Human Genetics.
Autor:
Pepper Dawes, Molly Smullen, Aria Fernandez-Fontaine, Yucheng Zhang, Jay English, Mohammed Uddin, ChangHui Pak, George M Church, Yingleong Chan, Elaine T Lim
Cerebral organoids are comprised of diverse cell types found in the developing human brain, and can be leveraged for the identification of critical cell types perturbed by genetic risk variants in common, neuropsychiatric disorders. There is great in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d395f8317bb3cbc91b66546359ec82
https://doi.org/10.21203/rs.3.rs-1825493/v1
https://doi.org/10.21203/rs.3.rs-1825493/v1
Autor:
Molly Smullen, Julia M Reichert, Pepper Dawes, Qi Wang, Benjamin Readhead, George M Church, Elaine T Lim, Yingleong Chan
Publikováno v:
SSRN Electronic Journal.
Inducing somatic cells into pluripotent stem cells (iPSCs) provides an excellent model for studying systems in-vitro. Understanding the impact of individual donor genetic backgrounds on reprogramming ability would allow researchers to harness these g