Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Molly S. Blevins"'
Publikováno v:
Analytical Chemistry. 94:14734-14744
Solvent-based ambient ionization mass spectrometry (MS) techniques provide a powerful approach for direct chemical analysis and molecular profiling of biological tissues. While molecular profiling of tissues has been widely used for disease diagnosis
Autor:
Molly S. Blevins, Samuel W. J. Shields, Wei Cui, Wedad Fallatah, Ann B. Moser, Nancy E. Braverman, Jennifer S. Brodbelt
Publikováno v:
Analytical Chemistry. 94:12621-12629
The biological impact of ether glycerophospholipids (GP) in peroxisomal disorders and other diseases makes them significant targets as biomarkers for diagnostic assays or deciphering pathology of the disorders. Ether lipids include both plasmanyl and
Autor:
Molly S. Blevins, Kyle J. Juetten, Virginia K. James, Jamie P. Butalewicz, Edwin E. Escobar, Michael B. Lanzillotti, James D. Sanders, Kyle L. Fort, Jennifer S. Brodbelt
Publikováno v:
Journal of Proteome Research. 21:2493-2503
The direct correlation between proteoforms and biological phenotype necessitates the exploration of mass spectrometry (MS)-based methods more suitable for proteoform detection and characterization. Here, we couple nano-hydrophobic interaction chromat
Autor:
Molly S. Blevins, Ross Thyer, Jennifer S. Brodbelt, Simon d'Oelsnitz, Andrew D. Ellington, Dustin R. Klein
Publikováno v:
Angew Chem Int Ed Engl
The catechol group of 3,4-dihydroxyphenylalanine (L-DOPA) derived from L-tyrosine oxidation is a key post-translational modification (PTM) in many protein biomaterials and has potential as a bioorthogonal handle for precision protein conjugation appl
Autor:
Jeffrey M. Schaub, Jennifer S. Brodbelt, Jada N. Walker, Ilya J. Finkelstein, Molly S. Blevins
Publikováno v:
Chemical Science
Protein–DNA interactions play crucial roles in DNA replication across all living organisms. Here, we apply a suite of mass spectrometry (MS) tools to characterize a protein-ssDNA complex, T4 gp32·ssDNA, with results that both support previous stud
Autor:
James D. Sanders, Samuel W. Shields, Edwin E. Escobar, Michael B. Lanzillotti, Jamie P. Butalewicz, Virginia K. James, Molly S. Blevins, Sarah N. Sipe, Jennifer S. Brodbelt
Publikováno v:
Analytical chemistry. 94(10)
The structural diversity of phospholipids plays a critical role in cellular membrane dynamics, energy storage, and cellular signaling. Despite its importance, the extent of this diversity has only recently come into focus, largely owing to advances i
Autor:
Martin V. Douglass, Molly S. Blevins, Dustin R. Klein, Luis A. Macias, M. Stephen Trent, Jennifer S. Brodbelt
Publikováno v:
Anal Chem
The need for detailed structural characterization of glycerophospholipids (GPLs) for many types of biologically motivated applications has led to the development of novel mass spectrometry-based methodologies that utilize alternative ion activation m
Autor:
Jennifer S. Brodbelt, Molly S. Blevins, Jeffrey T. Petty, Dahye Kim, Soonwoo Hong, Hsin-Chih Yeh, Christopher M. Crittenden
Publikováno v:
ACS Nano. 13:14070-14079
DNA-templated silver clusters (AgC) are fluorescent probes and biosensors whose electronic spectra can be tuned by their DNA hosts. However, the underlying rules that relate DNA sequence and struct...
Autor:
Alexandria B Purcell, M. Stephen Trent, Carmen M. Herrera, Virginia K James, Jennifer S. Brodbelt, Molly S. Blevins
Publikováno v:
Anal Chem
Glycerophospholipids (GPLs), one of the main components of bacterial cell membranes, exhibit high levels of structural complexity that are directly correlated with biophysical membrane properties such as permeability and fluidity. This structural com
Autor:
Molly S, Blevins, Dahye, Kim, Christopher M, Crittenden, Soonwoo, Hong, Hsin-Chih, Yeh, Jeffrey T, Petty, Jennifer S, Brodbelt
Publikováno v:
ACS nano. 13(12)
DNA-templated silver clusters (AgC) are fluorescent probes and biosensors whose electronic spectra can be tuned by their DNA hosts. However, the underlying rules that relate DNA sequence and structure to DNA-AgC fluorescence and photophysics are larg