Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Molly R. Seaward"'
Autor:
Jing Chen, Andreas Stahl, Nathan M Krah, Molly R Seaward, Jean-Sebastian Joyal, Aimee M Juan, Colman J Hatton, Christopher M Aderman, Roberta J Dennison, Keirnan L Willett, Przemyslaw Sapieha, Lois E H Smith
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30203 (2012)
Mutations in low-density lipoprotein receptor-related protein 5 (Lrp5) impair retinal angiogenesis in patients with familial exudative vitreoretinopathy (FEVR), a rare type of blinding vascular eye disease. The defective retinal vasculature phenotype
Externí odkaz:
https://doaj.org/article/b95b34056b594302b9b6d0fd3915b137
Autor:
Elisa Boscolo, Nathan M. Krah, Aimee M. Juan, Dorothy T. Pei, Przemyslaw Sapieha, Christian G. Hurst, Molly R. Seaward, Emily R. Greene, Jean-Sebastian Joyal, Jing Chen, Dipak Panigrahy, Andreas Stahl, Lois E.H. Smith, Roberta J. Dennison, Colman J. Hatton
Publikováno v:
Blood. 120:2925-2929
Inflammatory cytokines and growth factors drive angiogenesis independently; however, their integrated role in pathologic and physiologic angiogenesis is not fully understood. Suppressor of cytokine signaling-3 (SOCS3) is an inducible negative feedbac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e56a094f2b3f3a64006b68ce6f53e9
https://doi.org/10.1182/blood-2012-04-422527
https://doi.org/10.1182/blood-2012-04-422527
Autor:
Matthew Campbell, Roberta J. Dennison, Lois E.H. Smith, Aimee M. Juan, Akiko Mammoto, Jing Chen, Karen I. Guerin, C. M. Aderman, Keirnan L. Willett, Nathan M. Krah, Przemyslaw Sapieha, Colman J. Hatton, Jing Hua, Andreas Stahl, Molly R. Seaward
Publikováno v:
Circulation. 124:1871-1881
Background— Ischemic proliferative retinopathy, characterized by pathological retinal neovascularization, is a major cause of blindness in working-age adults and children. Defining the molecular pathways distinguishing pathological neovascularizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beabc6f899237df852b424ccda5f6dc8
https://doi.org/10.1161/circulationaha.111.040337
https://doi.org/10.1161/circulationaha.111.040337
Autor:
Karen I. Guerin, Nathan M. Krah, Przemyslaw Sapieha, Molly R. Seaward, Jing Chen, Roberta J. Dennison, Jing Hua, Lois E.H. Smith, Kip M. Connor, John Paul SanGiovanni, C. M. Aderman, Andreas Stahl, Keirnan L. Willett
Publikováno v:
Circulation Research. 107:495-500
Rationale: Omega3 long-chain polyunsaturated fatty acids (ω3-PUFAs) are powerful modulators of angiogenesis. However, little is known about the mechanisms governing ω3-PUFA–dependent attenuation of angiogenesis. Objective: This study aims to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad9b22d56b9407eb25a3bed419aee5b
https://doi.org/10.1161/circresaha.110.221317
https://doi.org/10.1161/circresaha.110.221317
Autor:
J-S Joyal, Molly R. Seaward, Lois E.H. Smith, James D Akula, Timothy S. Kern, Tara L. Favazza, Roberta J. Dennison, J. Tang, Przemyslaw Sapieha, Jing Chen, Aimee M. Juan, Nathan M. Krah, Colman J. Hatton, Andreas Stahl
Publikováno v:
Nutrition & Diabetes
Objective: Diabetic retinopathy (DR) is associated with hyperglycemia-driven microvascular pathology and neuronal compromise in the retina. However, DR is also linked to dyslipidemia. As omega-3 (ω-3) polyunsaturated fatty acids (PUFAs) are protecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf6bdfb3cc384c290375ec9ffcf6a38
https://pubmed.ncbi.nlm.nih.gov/23448719
https://pubmed.ncbi.nlm.nih.gov/23448719
Autor:
C. M. Aderman, Andreas Stahl, Molly R. Seaward, Nathan M. Krah, Przemyslaw Sapieha, Aimee M. Juan, Colman J. Hatton, Jean-Sebastian Joyal, Jing Chen, Keirnan L. Willett, Lois E.H. Smith, Roberta J. Dennison
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30203 (2012)
PLoS ONE
PLoS ONE
Mutations in low-density lipoprotein receptor-related protein 5 (Lrp5) impair retinal angiogenesis in patients with familial exudative vitreoretinopathy (FEVR), a rare type of blinding vascular eye disease. The defective retinal vasculature phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601d7470a501946301bd1e8cf137ed57
http://europepmc.org/articles/PMC3260226?pdf=render
http://europepmc.org/articles/PMC3260226?pdf=render
Autor:
Arianna Carughi, Kip M. Connor, C. M. Aderman, Elvira L. Liclican, Roberta J. Dennison, Molly R. Seaward, Yoshihide Kanaoka, Keirnan L. Willett, Lois E.H. Smith, Andreas Stahl, Karsten Gronert, John Paul SanGiovanni, Nathan M. Krah, Dalia Perelman, Przemyslaw Sapieha, Jing Chen
Publikováno v:
Science Translational Medicine. 3
Lipid signaling is dysregulated in many diseases with vascular pathology, including cancer, diabetic retinopathy, retinopathy of prematurity, and age-related macular degeneration. We have previously demonstrated that diets enriched in ω-3 polyunsatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5130a8da603e81c28410cf0019e9c9
https://doi.org/10.1126/scitranslmed.3001571
https://doi.org/10.1126/scitranslmed.3001571
Autor:
James D Akula, Tara L. Favazza, Chatarina Löfqvist, Huy Ong, Roberta J. Dennison, Felicitas Bucher, Lois E.H. Smith, Molly R. Seaward, Ann Hellström, Sylvain Chemtob, Nathan M. Krah, Jing Chen, Przemyslaw Sapieha, Andreas Stahl
Publikováno v:
The American journal of pathology. 177(6)
In clinical studies, postnatal weight gain is strongly associated with retinopathy of prematurity (ROP). However, animal studies are needed to investigate the pathophysiological mechanisms of how postnatal weight gain affects the severity of ROP. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39964e21979081022c87ab9d004630c9
https://pubmed.ncbi.nlm.nih.gov/21056995
https://pubmed.ncbi.nlm.nih.gov/21056995
Autor:
David A. Sinclair, Jing Chen, Molly R. Seaward, Aimee M. Juan, Jing Hua, Roberta J. Dennison, Shaday Michan, Przemyslaw Sapieha, Colman J. Hatton, Andreas Stahl, Lois E.H. Smith, Karen I. Guerin, Nathan M. Krah
Publikováno v:
Investigative Opthalmology & Visual Science. 52:2809
Abnormal retinal angiogenesis and choroidal angiogenesis are common causes of vision loss.1 Macular telangiectasia (MacTel), also known as idiopathic parafoveal telangiectasia, is a retinal neovascular disease in which there is abnormal retinal neova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517794e55fc21f114a2214212b442aff
https://doi.org/10.1167/iovs.10-6496
https://doi.org/10.1167/iovs.10-6496
Autor:
Keirnan L. Willett, Przemyslaw Sapieha, C. M. Aderman, Roberta J. Dennison, Ann Hellström, Jing Hua, Kip M. Connor, Molly R. Seaward, Chatarina Löfqvist, Jing Chen, Nathan M. Krah, Andreas Stahl, Karen I. Guerin, Lois E.H. Smith
Publikováno v:
Investigative Opthalmology & Visual Science. 51:2813
The mouse retina has been used extensively over the past decades to study both physiologic and pathologic angiogenesis. Over time, various mouse retina models have evolved into well-characterized and robust tools for in vivo angiogenesis research. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274bb587e036da175509d0aeaaa7d7d7
https://doi.org/10.1167/iovs.10-5176
https://doi.org/10.1167/iovs.10-5176