Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Molly R. Braun"'
Autor:
Molly R. Braun, Anne C. Moore, Jonathan D. Lindbloom, Katherine A. Hodgson, Emery G. Dora, Sean N. Tucker
Publikováno v:
Vaccines, Vol 12, Iss 9, p 955 (2024)
Therapeutic vaccination can harness the body’s cellular immune system to target and destroy cancerous cells. Several treatment options are available to eliminate pre-cancerous and cancerous lesions caused by human papillomaviruses (HPV), but may no
Externí odkaz:
https://doaj.org/article/13084199717a41a68551113613ad3ced
Autor:
Sarah N. Tedjakusuma, Colin A. Lester, Elena D. Neuhaus, Emery G. Dora, Samanta Gutierrez, Molly R. Braun, Sean N. Tucker, Becca A. Flitter
Publikováno v:
Vaccines, Vol 12, Iss 2, p 132 (2024)
As new SARS-CoV-2 variants continue to emerge and impact communities worldwide, next-generation vaccines that enhance protective mucosal immunity may have a significant impact on productive infection and transmission. We have developed recombinant no
Externí odkaz:
https://doaj.org/article/ecac1522101542b4941be4df1178c00a
Autor:
Molly R. Braun, Clarissa I. Martinez, Emery G. Dora, Laura J. Showalter, Annette R. Mercedes, Sean N. Tucker
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
SARS-CoV-2 variant clades continue to circumvent antibody responses elicited by vaccination or infection. Current parenteral vaccination strategies reduce illness and hospitalization, yet do not significantly protect against infection by the more rec
Externí odkaz:
https://doaj.org/article/582c61b3445c4c029cc2944d425903bc
Publikováno v:
Vaccines, Vol 10, Iss 4, p 593 (2022)
To effectively combat emerging infections and prevent future pandemics, next generation vaccines must be developed quickly, manufactured rapidly, and most critically, administered easily. Next generation vaccines need innovative approaches that preve
Externí odkaz:
https://doaj.org/article/8689341aae7f4ff28e554952e4950ed5
Autor:
Rachel Fearns, Emmeline L. Blanchard, Molly R. Braun, W. Evan Johnson, Philip J. Santangelo, Afzaal Shareef, Sarah L. Noton
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 5, p e1009589 (2021)
PLoS Pathogens, Vol 17, Iss 5, p e1009589 (2021)
Respiratory syncytial virus (RSV) is a major cause of respiratory disease in infants and the elderly. RSV is a non-segmented negative strand RNA virus. The viral M2-1 protein plays a key role in viral transcription, serving as an elongation factor to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3371403c7e68925392d9c162d376b6d2
https://doi.org/10.1371/journal.ppat.1009589
https://doi.org/10.1371/journal.ppat.1009589
Autor:
Stuart T. Nichol, Brett P. Eaton, Nate Larson, Ginger Donnelly, Mike Flint, Robert Jordan, Douglas L. Mayers, Michel Perron, Yeojin Park, Dustin Siegel, Lydia Wolfe, Veronica Soloveva, Edward Doerffler, William A. Lee, Donald K. Nichols, Dima N. Gharaibeh, Elizabeth C. Grimes, Laura Gomba, Darius Babusis, Travis K. Warren, Kwon Soo Chun, Tomas Cihlar, Queenie Wang, Adrian S. Ray, Kirsten M. Stray, Bruce Ross, Elyse R. Nagle, Kelly S. Stuthman, Lisa S. Welch, Rachel Fearns, Jonathan E. Nuss, Willard Lew, Jeffrey R. Kugelman, Molly R. Braun, Roy Bannister, Richard L. Mackman, Pamela Wong, Christina F. Spiropoulou, Joy Y. Feng, Hui Hon Chung, Ona Barauskas, Sean Neville, Jay Wells, Robert G. Strickley, Catherine L. Wilhelmsen, S. Swaminathan, Iva Trancheva, Nicole L. Garza, Cary Retterer, Michael K. Lo, Sean A. Van Tongeren, Gustavo Palacios, Laura K. McMullan, Amy C. Shurtleff, Lijun Zhang, Michael O. Clarke, Yili Xu, Sina Bavari, Tara Kenny, Ernest Carra, Rouzbeh Zamani, Shan Shan Chen
Publikováno v:
Nature
The most recent Ebola virus outbreak in West Africa, which was unprecedented in the number of cases and fatalities, geographic distribution, and number of nations affected, highlights the need for safe, effective, and readily available antiviral agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766327a9b5d4cc0d2298b57ff34377c6
http://europepmc.org/articles/PMC5551389
http://europepmc.org/articles/PMC5551389
Autor:
Aaron W. Lifland, Rachel Fearns, Daryll Vanover, Sarah L. Noton, Barbara Ludeke, Molly R. Braun, Chiara Zurla, Emmeline L. Blanchard, Philip J. Santangelo
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008987 (2020)
PLoS Pathogens
PLoS Pathogens
The ribonucleocapsid complex of respiratory syncytial virus (RSV) is responsible for both viral mRNA transcription and viral replication during infection, though little is known about how this dual function is achieved. Here, we report the use of a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ed4e36aaba27dfb453986a3f524bb9
https://doi.org/10.1371/journal.ppat.1008987
https://doi.org/10.1371/journal.ppat.1008987
Autor:
Yin Wang, Molly R. Braun, David C. Hooper, Rubén Monárrez, Yingmei Fu, Chun-Hsing Liao, George A. Jacoby, Ryo Okumura
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
Expression of the quinolone resistance gene qnrS1 is increased by quinolones, but unlike induction of some other qnr genes, the bacterial SOS system is not involved and no lexA box is found upstream. Nonetheless, at least 205 bp of upstream sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaa43cbf7df879c0554c98370637ff79
https://doi.org/10.1128/aac.00806-18
https://doi.org/10.1128/aac.00806-18
Autor:
Rubén, Monárrez, Yin, Wang, Yingmei, Fu, Chun-Hsing, Liao, Ryo, Okumura, Molly R, Braun, George A, Jacoby, David C, Hooper
Publikováno v:
Antimicrobial agents and chemotherapy. 62(9)
Expression of the quinolone resistance gene qnrS1 is increased by quinolones, but unlike induction of some other qnr genes, the bacterial SOS system is not involved and no lexA box is found upstream. Nonetheless, at least 205 bp of upstream sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2099b3fcc414b6552ed3edf14431fc3f
https://pubmed.ncbi.nlm.nih.gov/29914953
https://pubmed.ncbi.nlm.nih.gov/29914953
Autor:
Chadene Z. Tremaglio, Michael E. Mawhorter, Molly R. Braun, Rachel Fearns, Laure R. Deflubé, Sarah L. Noton
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 12, p e1006803 (2017)
PLoS Pathogens, Vol 13, Iss 12, p e1006803 (2017)
The large polymerase subunit (L) of non-segmented negative strand RNA viruses transcribes viral mRNAs and replicates the viral genome. Studies with VSV have shown that conserved region V (CRV) of the L protein is part of the capping domain. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3faf6eac20ba0d32bd38f8087e2d296a
https://pubmed.ncbi.nlm.nih.gov/29281742
https://pubmed.ncbi.nlm.nih.gov/29281742