Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Molly O, Riegert"'
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Achromobacter xylosoxidans is an opportunistic pathogen implicated in a wide variety of human infections including the ability to colonize the lungs of cystic fibrosis (CF) patients. The role of A. xylosoxidans in human pathology remains con
Externí odkaz:
https://doaj.org/article/c32c5c8c4c27470a8bd36eb9dd331d92
Autor:
Brandon M. Wills, Preeti Garai, Molly O. Riegert, Felix T. Sanchez, Adam M. Pickrum, Dara W. Frank, Kenneth L. Brockman
Publikováno v:
Infection and Immunity.
Achromobacter xylosoxidans (Ax) is an opportunistic pathogen and causative agent of numerous infections particularly in immunocompromised individuals with increasing prevalence in cystic fibrosis (CF). To date, investigations have focused on the clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19c6aef9125dd2763e2d45439d1da76a
https://doi.org/10.1128/iai.00037-23
https://doi.org/10.1128/iai.00037-23
Publikováno v:
Microbiology spectrum. 10(4)
Achromobacter xylosoxidans is an opportunistic pathogen implicated in a wide variety of human infections including the ability to colonize the lungs of cystic fibrosis (CF) patients. The role of A. xylosoxidans in human pathology remains controversia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6782dde994f6b0013d37eeae636a24b0
https://pubmed.ncbi.nlm.nih.gov/35856670
https://pubmed.ncbi.nlm.nih.gov/35856670
Autor:
Samuel A. DeCero, Jens Meiler, Diego del Alamo, Molly O. Riegert, Jimmy B. Feix, Maxx H. Tessmer, Dara W. Frank
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
ExoU, a type III secreted phospholipase effector of Pseudomonas aeruginosa, serves as a prototype to model large, dynamic, membrane-associated proteins. ExoU is synergistically activated by interactions with membrane lipids and ubiquitin. To dissect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7850a7562896f3e9eed430f10686150
https://doi.org/10.1038/s41598-020-76023-3
https://doi.org/10.1038/s41598-020-76023-3
Autor:
Maxx H. Tessmer, Aaron T. Dirck, Dara W. Frank, Nathan A. Ledeboer, Adam M. Pickrum, John R. Kirby, Molly O. Riegert, Orlando DeLeon, Julie Biller
Publikováno v:
Infect Immun
Achromobacter xylosoxidans is increasingly recognized as a colonizer of cystic fibrosis (CF) patients, but the role that A. xylosoxidans plays in pathology remains unknown. This knowledge gap is largely due to the lack of model systems available to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c1951f239564281c2ec1df215cfd92
https://doi.org/10.1128/iai.00136-20
https://doi.org/10.1128/iai.00136-20
Autor:
Jimmy B. Feix, Jens Meiler, Rocco Moretti, David M. Anderson, Dara W. Frank, Adam M. Pickrum, Maxx H. Tessmer, Molly O. Riegert
Publikováno v:
Proceedings of the National Academy of Sciences. 115:525-530
ExoU is a type III-secreted cytotoxin expressing A2 phospholipase activity when injected into eukaryotic target cells by the bacterium Pseudomonas aeruginosa. The enzymatic activity of ExoU is undetectable in vitro unless ubiquitin, a required cofact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddef66f6cdb7a025f639b5e6def0e063
https://doi.org/10.1073/pnas.1716861115
https://doi.org/10.1073/pnas.1716861115
Publikováno v:
Journal of Bacteriology. 201
ExoU is a potent type III secretion system effector that is injected directly into mammalian cells by the opportunistic pathogen Pseudomonas aeruginosa. As a ubiquitin-activated phospholipase A2 (PLA2), ExoU exhibits cytotoxicity by cleaving membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a4d1e4fbaa7c6e6a15afe1c4f8ed67
https://doi.org/10.1128/jb.00623-18
https://doi.org/10.1128/jb.00623-18