Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Molly M. Morgan"'
Autor:
Brian P. Johnson, Ross A. Vitek, Molly M. Morgan, Dustin M. Fink, Tyler G. Beames, Peter G. Geiger, David J. Beebe, Robert J. Lipinski
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Paracrine signaling in the tissue microenvironment is a central mediator of morphogenesis, and modeling this dynamic intercellular activity in vitro is critical to understanding normal and abnormal development. For example, Sonic Hedgehog (Shh) signa
Externí odkaz:
https://doaj.org/article/d8b3b36fea6a41af81b6b68e4013d24d
Autor:
Molly M. Morgan, Megan K. Livingston, Jay W. Warrick, Eli M. Stanek, Elaine T. Alarid, David J. Beebe, Brian P. Johnson
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract The estrogen receptor (ER) regulates the survival and growth of breast cancer cells, but it is less clear how components of the tissue microenvironment affect ER-mediated responses. We set out to test how human mammary fibroblasts (HMFs) mod
Externí odkaz:
https://doaj.org/article/93d31729cd3141899c8dc7350744dfce
Autor:
Sheena C. Kerr, Brian P. Johnson, Megan K. Livingston, Molly M. Morgan, Karina M. Lugo-Cintrón, Amani A. Gillette, Melissa C. Skala, Joshua M. Lang, Logan Florek, David J. Beebe, Peter F. Favreau
Publikováno v:
Integrative Biology
The prostate tumor microenvironment (TME) is strongly immunosuppressive; it is largely driven by alteration in cell phenotypes (i.e. tumor-associated macrophages and exhausted cytotoxic T cells) that result in pro-tumorigenic conditions and tumor gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297b85c4b73e3636a1974308a5577abf
https://doi.org/10.1093/intbio/zyaa020
https://doi.org/10.1093/intbio/zyaa020
Autor:
Elaine T. Alarid, Brian P. Johnson, Linda A. Schuler, David J. Beebe, Molly M. Morgan, Jordan C. Ciciliano
Publikováno v:
Integr Biol (Camb)
Accumulating evidence suggests that our ability to predict chemical effects on breast cancer is limited by a lack of physiologically relevant in vitro models; the typical in vitro breast cancer model consists of the cancer cell and excludes the mamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d7264dcd63c2ad32367657cf0cbec1
https://doi.org/10.1093/intbio/zyaa002
https://doi.org/10.1093/intbio/zyaa002
Publikováno v:
The FASEB Journal. 33:8623-8633
Aromatase inhibitors are the preferred treatment for certain women with estrogen receptor (ER)-positive breast cancer, but evidence suggests that women with obesity experience aromatase inhibitor resistance at higher rates. To compare how stromal cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb1b3607b567710f216700fe8c5bdd82
https://doi.org/10.1096/fj.201802347rrr
https://doi.org/10.1096/fj.201802347rrr
Autor:
Brian P. Johnson, Ross A. Vitek, Molly M. Morgan, Dustin M. Fink, Tyler G. Beames, Peter G. Geiger, David J. Beebe, Robert J. Lipinski
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Paracrine signaling in the tissue microenvironment is a central mediator of morphogenesis, and modeling this dynamic intercellular activityin vitrois critical to understanding normal and abnormal development. For example, Sonic Hedgehog (Shh) signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88fe1c3021009a6c8b2c3c988ac11612
https://pubmed.ncbi.nlm.nih.gov/33634122
https://pubmed.ncbi.nlm.nih.gov/33634122
Autor:
William T. Daly, William L. Murphy, María Virumbrales-Muñoz, Megan K. Livingston, Brian P. Johnson, Molly M. Morgan, David J. Beebe
Publikováno v:
ACS biomaterials scienceengineering. 5(11)
Extracellular matrix (ECM) mimicking hydrogel scaffolds have greatly improved the physiological relevance of in vitro assays, but introduce another dimension that creates variability in cell related readouts when compared to traditional 2D cells-on-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b7167b224d406bdf83538c940cb0ce
https://pubmed.ncbi.nlm.nih.gov/31942444
https://pubmed.ncbi.nlm.nih.gov/31942444
Autor:
Ismael Gomez, David J. Beebe, Jose M. Ayuso, Kari B. Wisinski, Suehelay Acevedo-Acevedo, Molly M. Morgan, Tiffany M. Heaster, Melissa C. Skala, Sean P. Palecek, Karina M. Lugo-Cintrón, Amani A. Gillette
Publikováno v:
EBioMedicine
Background Ductal carcinoma in situ (DCIS) is the earliest stage of breast cancer. During DCIS, tumor cells remain inside the mammary duct, growing under a microenvironment characterized by hypoxia, nutrient starvation, and waste product accumulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0530284be7f7a1cf0e414ce9c47ee8
https://doi.org/10.1016/j.ebiom.2018.10.046
https://doi.org/10.1016/j.ebiom.2018.10.046
Autor:
Ana M. Reyes-Ramos, Karla P Ramos-Cruz, Molly M. Morgan, Yatao Shi, Maribella Domenech, Yasmín R. Álvarez-García, Loren E. Stallcop, David J. Beebe, Jay W. Warrick, Lingjun Li
Publikováno v:
Lab on a Chip. 18:451-462
Tape-based razor-printing is a flexible and affordable ultra-rapid prototyping approach for microscale device fabrication. However, integration of this prototyping approach into cell-based assay development has been limited to proof of principle demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4578bcb96ad1c3e9566ae99a3d31c88
https://doi.org/10.1039/c7lc00724h
https://doi.org/10.1039/c7lc00724h
Autor:
Joshua M. Lang, David J. Beebe, Jaime M. Sperger, Zachery D. Schultz, Charlotte N. Stahlfeld, Molly M. Morgan, Anupama Singh, Rory M. Bade, Jennifer L. Schehr, Madalyn S. Gill, Jay W. Warrick, Hannah M. Pezzi
Publikováno v:
Clinical Cancer Research. 26:B40-B40
The efficacy of androgen receptor (AR) signaling inhibitors (ARSIs) in prostate cancer is limited by both de novo and acquired resistance. Two well-described mechanisms of resistance to ARSIs are the development of constitutively activated AR splice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11a26d2ee214e4fa2c3d3cb51d6abf90
https://doi.org/10.1158/1557-3265.liqbiop20-b40
https://doi.org/10.1158/1557-3265.liqbiop20-b40