Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Molly M. Hannigan"'
Publikováno v:
Cell Reports, Vol 19, Iss 12, Pp 2598-2612 (2017)
Summary: Alternative splicing has essential roles in development. Remarkably, spermatogenic cells express more alternatively spliced RNAs compared to most whole tissues; however, regulation of these RNAs remains unclear. Here, we characterize the alt
Externí odkaz:
https://doaj.org/article/9be5f538bbf84ebd80e46194f28609ea
Autor:
Molly M. Hannigan, J. Will Thompson, Christopher V. Nicchitta, Tianli Zheng, Alyson M. Hoffman
Publikováno v:
Mol Cell Proteomics
Protein synthesis on the endoplasmic reticulum (ER) requires the dynamic coordination of numerous cellular components. Together, resident ER membrane proteins, cytoplasmic translation factors, and both integral membrane and cytosolic RNA-binding prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739aac3a36584fedbdd42892f0001904
https://doi.org/10.1074/mcp.ra120.002228
https://doi.org/10.1074/mcp.ra120.002228
Autor:
Peng Yu, Steven T. Sizemore, Ruth A. Keri, Kristen L. Weber-Bonk, Darcie D. Seachrist, Vinay Varadan, Bryan M. Webb, Gurkan Bebek, Molly M. Hannigan, Natasha N. Ingles, Salendra Singh, Donny D. Licatalosi
Publikováno v:
J Biol Chem
The phenotypes of each breast cancer subtype are defined by their transcriptomes. However, the transcription factors that regulate differential patterns of gene expression that contribute to specific disease outcomes are not well understood. Here, us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d27ea8dcd4920dd5e1b08ade8751e7
https://doi.org/10.1074/jbc.ra120.014018
https://doi.org/10.1074/jbc.ra120.014018
Publikováno v:
Quantitative Biology. 6:228-238
BACKGROUND: Our understanding of post-transcriptional gene regulation has increased exponentially with the development of robust methods to define protein-RNA interactions across the transcriptome. In this review, we highlight the evolution and succe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba292b12db58972c380d741fb01aeeb2
https://doi.org/10.1007/s40484-018-0145-6
https://doi.org/10.1007/s40484-018-0145-6
Publikováno v:
Cell Reports, Vol 19, Iss 12, Pp 2598-2612 (2017)
Summary: Alternative splicing has essential roles in development. Remarkably, spermatogenic cells express more alternatively spliced RNAs compared to most whole tissues; however, regulation of these RNAs remains unclear. Here, we characterize the alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60020b9b498d8b03944571650afacb9d
https://doi.org/10.1016/j.celrep.2017.05.089
https://doi.org/10.1016/j.celrep.2017.05.089
The RNA binding protein PTBP2 (polypyrimidine tract binding protein 2) is a key regulator of tissue-specific alternative RNA splicing. In the testis, PTBP2 is expressed in meiotic and post-meiotic germ cells (spermatocytes and spermatids, respectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357002f49e274bd395cec9612f65f70d
https://doi.org/10.1101/497461
https://doi.org/10.1101/497461
Autor:
Raul Jobava, Leah L. Zagore, Chaolin Zhang, Molly M. Hannigan, Maria Hatzoglou, Sebastien M. Weyn-Vanhentenryck, Donny D. Licatalosi, Thomas J. Sweet
Publikováno v:
Cell reports
SUMMARY The RNA binding protein DAZL is essential for gametogenesis, but its direct in vivo functions, RNA targets, and the molecular basis for germ cell loss in Dazl-null mice are unknown. Here, we mapped transcriptome-wide DAZL-RNA interactions in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575482311c1ae449597f0f978ceff275
https://doi.org/10.1101/273292
https://doi.org/10.1101/273292
Publikováno v:
Cancer Research. 78:32-32
Cancer stem cells (CSC) contribute to the high incidence of metastatic recurrence in triple-negative breast cancer (TNBC) and elucidating the mechanisms controlling CSC properties should provide novel targets for therapeutic development that improves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57be7c2fd7cc37bf04e8387c707027d9
https://doi.org/10.1158/1538-7445.am2018-32
https://doi.org/10.1158/1538-7445.am2018-32
Autor:
Donny D. Licatalosi, Molly M. Hannigan, Qin Li, Sarah E. Grabinski, R. Michael Sramkoski, Leah L. Zagore, Thomas J. Sweet
Publikováno v:
Molecular and cellular biology. 35(23)
RNA binding proteins (RBPs) are increasingly recognized as essential factors in tissue development and homeostasis. The polypyrimidine tract binding (PTB) protein family of RBPs are important posttranscriptional regulators of gene expression. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c605d1ea643c6748eb173f0601aa62e6
https://pubmed.ncbi.nlm.nih.gov/26391954
https://pubmed.ncbi.nlm.nih.gov/26391954
Autor:
McKernan CM; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA., Khatri A; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Hannigan M; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA., Child J; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA., Chen Q; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA., Mayro B; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA., Snyder D; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA., Nicchitta CV; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA., Pendergast AM; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address: ann.pendergast@duke.edu.
Publikováno v:
Cell reports [Cell Rep] 2022 Aug 30; Vol. 40 (9), pp. 111268.