Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Molly L. Bucklin"'
Autor:
Andrew J. Takeda, Timothy J. Maher, Yu Zhang, Stephen M. Lanahan, Molly L. Bucklin, Susan R. Compton, Paul M. Tyler, William A. Comrie, Makoto Matsuda, Kenneth N. Olivier, Stefania Pittaluga, Joshua J. McElwee, Debra A. Long Priel, Douglas B. Kuhns, Roger L. Williams, Peter J. Mustillo, Matthias P. Wymann, V. Koneti Rao, Carrie L. Lucas
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Causally linking a mutation to clinical phenotypes in rare hereditary diseases is both challenging and illuminating. Here the authors identify PI3Kɣ mutations in a patient with immune dysregulation, and recapitulate the phenotypes in PI3Kɣ-deficien
Externí odkaz:
https://doaj.org/article/e5661652c92a434e8616129d00386c3f
Autor:
Mengting Zhao, Molly L. Bucklin, Iris H I M Hollink, Anne M. Griffiths, Jie Pan, Jason Catanzaro, Neil Warner, Saquib A. Lakhani, Timothy J. Maher, Aleixo M. Muise, Raffaella A. Morotti, Virgil A. S. H. Dalm, Andrew J. Rice, Carrie L. Lucas, Paul L. McCarthy, Weizhen Ji, Paul M. Tyler, Annemarie M.C. van Rossum
Publikováno v:
Nature Immunology, 22(9), 1118-1126. Nature Publishing Group
Nat Immunol
Nat Immunol
Transcription factors specialized to limit the destructive potential of inflammatory immune cells remain ill-defined. We discovered loss-of-function variants in the X-linked ETS transcription factor gene ELF4 in multiple unrelated male patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b53c6832e3ec633b40efececdc8141
https://pure.eur.nl/en/publications/a21ed0e4-3178-4459-83f5-3025a15e9c0c
https://pure.eur.nl/en/publications/a21ed0e4-3178-4459-83f5-3025a15e9c0c
Autor:
Yu Zhang, Susan R Compton, Molly L. Bucklin, William A. Comrie, Peter Mustillo, Makoto Matsuda, Kenneth N. Olivier, Matthias P. Wymann, V. Koneti Rao, Debra A. Long Priel, Timothy J. Maher, Roger L. Williams, Stephen M. Lanahan, Stefania Pittaluga, Paul M. Tyler, Douglas B. Kuhns, Carrie L. Lucas, Andrew J. Takeda, Joshua McElwee
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
Phosphatidylinositol 3-kinase-gamma (PI3Kγ) is highly expressed in leukocytes and is an attractive drug target for immune modulation. Different experimental systems have led to conflicting conclusions regarding inflammatory and anti-inflammatory fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f75a1234b0e4a1578404b07a8bac63
https://doi.org/10.1038/s41467-019-12311-5
https://doi.org/10.1038/s41467-019-12311-5
Autor:
Chantal B.F. Vogels, Anne E. Watkins, Christina A. Harden, Doug E. Brackney, Jared Shafer, Jianhui Wang, César Caraballo, Chaney C. Kalinich, Isabel M. Ott, Joseph R. Fauver, Eriko Kudo, Peiwen Lu, Arvind Venkataraman, Maria Tokuyama, Adam J. Moore, M. Catherine Muenker, Arnau Casanovas-Massana, John Fournier, Santos Bermejo, Melissa Campbell, Rupak Datta, Allison Nelson, Charles S. Dela Cruz, Albert I. Ko, Akiko Iwasaki, Harlan M. Krumholz, J.D. Matheus, Pei Hui, Chen Liu, Shelli F. Farhadian, Robby Sikka, Anne L. Wyllie, Nathan D. Grubaugh, Kelly Anastasio, Michael H. Askenase, Maria Batsu, Sean Bickerton, Kristina Brower, Molly L. Bucklin, Staci Cahill, Yiyun Cao, Edward Courchaine, Giuseppe DeIuliis, Rebecca Earnest, Bertie Geng, Benjamin Goldman-Israelow, Ryan Handoko, William Khoury-Hanold, Daniel Kim, Lynda Knaggs, Maxine Kuang, Sarah Lapidus, Joseph Lim, Melissa Linehan, Alice Lu-Culligan, Anjelica Martin, Irene Matos, David McDonald, Maksym Minasyan, Maura Nakahata, Nida Naushad, Jessica Nouws, Abeer Obaid, Camila Odio, Ji Eun Oh, Saad Omer, Annsea Park, Hong-Jai Park, Xiaohua Peng, Mary Petrone, Sarah Prophet, Tyler Rice, Kadi-Ann Rose, Lorenzo Sewanan, Lokesh Sharma, Albert C. Shaw, Denise Shepard, Mikhail Smolgovsky, Nicole Sonnert, Yvette Strong, Codruta Todeasa, Jordan Valdez, Sofia Velazquez, Pavithra Vijayakumar, Elizabeth B. White, Yexin Yang
Publikováno v:
Med (New York, N.y.)
Background Scaling SARS-CoV-2 testing to meet demands of safe reopenings continues to be plagued by assay costs and supply chain shortages. In response, we developed SalivaDirect, which received Emergency Use Authorization (EUA) from the U.S. Food an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bb1cb0e9fb9f8a886a6b12c59f8243
https://doi.org/10.1016/j.medj.2020.12.010
https://doi.org/10.1016/j.medj.2020.12.010