Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Molly K. McLendon"'
Autor:
Daniel V. Zurawski, Molly K. McLendon
Publikováno v:
Antibiotics, Vol 9, Iss 4, p 155 (2020)
In the beginning of the 21st century, the frequency of antimicrobial resistance (AMR) has reached an apex, where even 4th and 5th generation antibiotics are becoming useless in clinical settings. In turn, patients are suffering from once-curable infe
Externí odkaz:
https://doaj.org/article/2ed8174681cd40bd9eb3a77112d6424c
Publikováno v:
Applied and Environmental Microbiology. 74:2637-2645
Francisella tularensis is the etiologic agent of an intracellular systemic infection of the lymphatic system in humans called tularemia. The organism has become the subject of considerable research interest due to its classification as a category A s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061fb88f66d67458ea1ee032363bb2b7
https://doi.org/10.1128/aem.02882-07
https://doi.org/10.1128/aem.02882-07
Publikováno v:
Infection and Immunity. 75:5518-5531
Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria, and the lipid A region of LPS mediates stimulation of the immune system in a structure-dependent manner. Unlike the LPS of many other gram-negative bacteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9188af4058c3c857a6ff019d2a37f864
https://doi.org/10.1128/iai.01288-06
https://doi.org/10.1128/iai.01288-06
Autor:
Michael A. Apicella, Birgit Schilling, Bradford W. Gibson, Nancy J. Phillips, Molly K. McLendon
Publikováno v:
Analytical Chemistry. 79:1034-1042
Lipopolysaccharide (LPS) is a major component of the outer membrane of Gram-negative bacteria. The lipid A region of LPS stimulates the immune system in a structure-dependent manner. We have previously identified the two major lipid A species from Fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f37e9c9878b427c6b5d8b509af89193b
https://doi.org/10.1021/ac061654e
https://doi.org/10.1021/ac061654e
Autor:
Bradford W. Gibson, Michael A. Apicella, Birgit Schilling, Molly K. McLendon, Nancy J. Phillips
Publikováno v:
Infection and Immunity. 72:5340-5348
We have investigated the lipid A of Francisella tularensis subsp. holarctica strain 1547-57, a type B strain, by using matrix-assisted laser desorption ionization-time-of-flight mass spectrometry, nanoelectrospray quadrupole ion-trap mass spectrometr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6efcbaa0a2e86e163d0349197e44486
https://doi.org/10.1128/iai.72.9.5340-5348.2004
https://doi.org/10.1128/iai.72.9.5340-5348.2004
Autor:
Molly K. McLendon, Gretchen Berg, Aloka B. Bandara, Thomas J. Inzana, Michael A. Apicella, Anna E. Champion, Parastoo Azadi, Xiaoshan Wang, D. Scott Snyder
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19003 (2011)
PLoS ONE
PLoS ONE
Background Francisella tularensis is a category-A select agent and is responsible for tularemia in humans and animals. The surface components of F. tularensis that contribute to virulence are not well characterized. An electron-dense capsule has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc976d7814dc6530a84137e9744246c
http://europepmc.org/articles/PMC3081320?pdf=render
http://europepmc.org/articles/PMC3081320?pdf=render
Autor:
Sayaka Imagawa, Bradford W. Gibson, Thomas J. Inzana, Jason Hunt, Dara W. Frank, Bradley D. Jones, Biswa Choudhury, Michael A. Apicella, Michael P. Jennings, Molly K. McLendon, Deborah M. B. Post, Jed A. Rasmussen, Andrew C. Fowler, Kathryn Chaloner, Tamara M. Maier, Thomas C. Zahrt
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11060 (2010)
PLoS ONE
PLoS ONE
Capsular polysaccharides are important factors in bacterial pathogenesis and have been the target of a number of successful vaccines. Francisella tularensis has been considered to express a capsular antigen but none has been isolated or characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544955925f54eeabec82508e2df34204
https://hdl.handle.net/10919/85820
https://hdl.handle.net/10919/85820
Publikováno v:
Journal of leukocyte biology. 82(4)
Francisella tularensis, a designated Category A biological agent, can cause severe infection in humans. Previous studies have demonstrated a significant immunoprotective role for B lymphocytes in animal models, but the responses of human B lymphocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4653e352a49b563ae4f37bfa3332e3ac
https://pubmed.ncbi.nlm.nih.gov/17634278
https://pubmed.ncbi.nlm.nih.gov/17634278
Publikováno v:
Infection and immunity. 75(6)
In observing Francisella tularensis interactions with nonphagocytic cell lines in vitro, we noted significant adherence, invasion, and intracellular growth of the bacteria within these cells. F. tularensis live vaccine strain invasion of nonprofessio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a836836de2faa84d4f417be47ac34c90
https://pubmed.ncbi.nlm.nih.gov/17339345
https://pubmed.ncbi.nlm.nih.gov/17339345
Autor:
Birgit, Schilling, Molly K, McLendon, Nancy J, Phillips, Michael A, Apicella, Bradford W, Gibson
Publikováno v:
Analytical chemistry. 79(3)
Lipopolysaccharide (LPS) is a major component of the outer membrane of Gram-negative bacteria. The lipid A region of LPS stimulates the immune system in a structure-dependent manner. We have previously identified the two major lipid A species from Fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::691f31caaff3533f92b6b571a1036d2c
https://pubmed.ncbi.nlm.nih.gov/17263332
https://pubmed.ncbi.nlm.nih.gov/17263332