Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Molly Javier Uyeda"'
Autor:
Molly Javier Uyeda, Robert A. Freeborn, Brandon Cieniewicz, Rosa Romano, Ping (Pauline) Chen, Jeffrey Mao-Hwa Liu, Benjamin Thomas, Esmond Lee, Alma-Martina Cepika, Rosa Bacchetta, Maria Grazia Roncarolo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Type 1 regulatory T (Tr1) cells are subset of peripherally induced antigen-specific regulatory T cells. IL-10 signaling has been shown to be indispensable for polarization and function of Tr1 cells. However, the transcriptional machinery underlying h
Externí odkaz:
https://doaj.org/article/a593a36a62d447bfa034987c38a5f272
Autor:
Brandon Cieniewicz, Molly Javier Uyeda, Ping (Pauline) Chen, Ece Canan Sayitoglu, Jeffrey Mao-Hwa Liu, Grazia Andolfi, Katharine Greenthal, Alice Bertaina, Silvia Gregori, Rosa Bacchetta, Norman James Lacayo, Alma-Martina Cepika, Maria Grazia Roncarolo
Publikováno v:
Haematologica, Vol 106, Iss 10 (2020)
Type 1 regulatory (Tr1) T cells induced by enforced expression of IL-10 (LV-10) are being developed as a novel treatment for chemotherapy-resistant myeloid leukemias. In vivo, LV-10 cells do not cause graft vs host disease while mediating graft vs le
Externí odkaz:
https://doaj.org/article/36e365e063aa4a8e97de88d9ff41282b
Autor:
Alice Bertaina, Silvia Gregori, Katharine Greenthal, Ece Canan Sayitoglu, Jeffrey Liu, Brandon Cieniewicz, Maria Grazia Roncarolo, Ping Pauline Chen, Alma-Martina Cepika, Norman J. Lacayo, Grazia Andolfi, Molly Javier Uyeda, Rosa Bacchetta
Publikováno v:
Haematologica
Type 1 regulatory (Tr1) T cells induced by enforced expression of interleukin-10 (LV-10) are being developed as a novel treatment for chemotherapy-resistant myeloid leukemias. In vivo, LV-10 cells do not cause graft-versus-host disease while mediatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018a38f8859eee1589872b027918de9a
http://europepmc.org/articles/PMC8485690
http://europepmc.org/articles/PMC8485690
Coexpression of CD163 and CD141 identifies human circulating IL-10-producing dendritic cells (DC-10)
Autor:
Silvia Gregori, Matteo Floris, Daniele Avancini, Francesca Romana Santoni de Sio, Daniela Tomasoni, Maria Grazia Roncarolo, Alessandro Bulfone, Matteo Villa, Michela Comi, Molly Javier Uyeda
Publikováno v:
Cellular and Molecular Immunology
Tolerogenic dendritic cells (DCs) are key players in maintaining immunological homeostasis, dampening immune responses, and promoting tolerance. DC-10, a tolerogenic population of human IL-10-producing DCs characterized by the expression of HLA-G and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d088454107b177201c3315f7e81894
https://doi.org/10.1038/s41423-019-0218-0
https://doi.org/10.1038/s41423-019-0218-0
Autor:
Alma-Martina Cepika, Molly Javier Uyeda, Yohei Sato, Rosa Bacchetta, Maria Grazia Roncarolo, Jeffrey Liu
Publikováno v:
Journal of Allergy and Clinical Immunology. 142:1679-1695
Monogenic diseases of the immune system, also known as inborn errors of immunity, are caused by single-gene mutations resulting in immune deficiency and dysregulation. More than 350 diseases have been described to date, and the number is rapidly expa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12643c41bf8d68ddb7f76728a92f5e26
https://doi.org/10.1016/j.jaci.2018.10.026
https://doi.org/10.1016/j.jaci.2018.10.026
Autor:
Jeffrey Liu, Benjamin Craig Thomas, Ece Canan Sayitoglu, Rosa Bacchetta, Ping Chen, Brandon Cieniewicz, Yohei Sato, Alma-Martina Cepika, Maria Grazia Roncarolo, Molly Javier Uyeda
Publikováno v:
Cytotherapy
Background aims Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative therapeutic approach for many hematological disorders. However, allo-HSCT is frequently accompanied by a serious side effect: graft-versus-host disease (GVHD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ada1eb65e0496d34cf2865fa93f54cd
https://pubmed.ncbi.nlm.nih.gov/34404616
https://pubmed.ncbi.nlm.nih.gov/34404616
Autor:
Alice Bertaina, Laura Amaya, Maria Grazia Roncarolo, Alma-Martina Cepika, Rajni Agarwal-Hashmi, Mark M. Davis, David M. Louis, Rosa Bacchetta, Mansi Narula, Everett Meyer, Molly Javier Uyeda, Liwen Xu, Pauline P. Chen, Brandon Cieniewicz, Xuhuai Ji
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Graft-vs-host-disease (GvHD) is a life-threatening complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT), limiting the use of this potentially curative treatment for hematological malignancies. To address this, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212e053736e83c17e18816d788c12699
https://doi.org/10.1136/jitc-2020-sitc2020.0146
https://doi.org/10.1136/jitc-2020-sitc2020.0146
Autor:
Maria Grazia Roncarolo, Michael Snyder, Alice Bertaina, Silvia Gregori, Yohei Sato, Laura Passerini, Rosa Bacchetta, Molly Javier Uyeda, Marianne Goodwin, Brian D. Piening
Publikováno v:
Clinical & Translational Immunology
Objectives Genetic or acquired defects in FOXP3+ regulatory T cells (Tregs) play a key role in many immune‐mediated diseases including immune dysregulation polyendocrinopathy, enteropathy, X‐linked (IPEX) syndrome. Previously, we demonstrated CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9169caad0f8b94587e18c39d1100d3
https://doi.org/10.1002/cti2.1214
https://doi.org/10.1002/cti2.1214
Autor:
Takashi Sado, Giancarlo Bonora, Molly Javier Uyeda, Vincent Pasque, Anupama Sadhu Dimashkie, Alexander Meissner, Bernadett Papp, Takashi Tada, Dana Case, Ryan Schmidt, Sanjeet G. Patel, Ritchie Ho, Jason Tchieu, Rahul Karnik, Robin McKee, Kathrin Plath
Publikováno v:
Cell, vol 159, iss 7
SummaryReprogramming to iPSCs resets the epigenome of somatic cells, including the reversal of X chromosome inactivation. We sought to gain insight into the steps underlying the reprogramming process by examining the means by which reprogramming lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab32f4ce74289e5109efd610c479eec0
https://europepmc.org/articles/PMC4282187/
https://europepmc.org/articles/PMC4282187/
