Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Molly J. Price-Jones"'
Publikováno v:
SLAS Discovery. 3:227-230
Cytostar-T scintillating microplates allow the real time analysis of cell associated phenomena, such as agonist induced ion flux. However, due to the time lag involved in adding agonist to cells before loading on to a microplate counter, it has not b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ce8ad4793beab83935f6116bdd12e93
https://doi.org/10.1177/108705719800300309
https://doi.org/10.1177/108705719800300309
Publikováno v:
Methods in Molecular Biology ISBN: 9781617799082
Scintillation proximity assay (SPA) is a bead-based homogeneous assay technology that removes the need for a filtration step to separate bound from free ligand in a receptor binding assay. SPA allows the rapid and sensitive assay of a wide range of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8efe535b40504ef8d19ab1ccbe5292f2
https://doi.org/10.1007/978-1-61779-909-9_4
https://doi.org/10.1007/978-1-61779-909-9_4
Autor:
Gary Clements, John Kay, John P. Moore, Molly J. Price-Jones, Thomas F. Schulz, Myra O. McClure, Robin A. Weiss, Mark Marsh, Christopher Sutton, Paul E. Stephens, Susan Thomson, Paul R. Clapham, Jane A. McKeating
Publikováno v:
Europe PubMed Central
Located close to the crown of the V3 type-specific neutralization loop of the human immunodeficiency virus type 1 (HIV-1) (IIIB) SU glycoprotein gp120, are several potential sites that should be susceptible to proteolytic cleavage by enzymes of tryps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb87a1e3d2fd8cc64ed183e55decfcc
https://doi.org/10.1089/aid.1991.7.3
https://doi.org/10.1089/aid.1991.7.3
Autor:
Marvin D. Schulman, Molly J. Price-Jones, Anne Fowler, John Anson, Russell B. Lingham, Kelvin T. Hughes
Publikováno v:
Journal of biomolecular screening. 5(3)
A screening assay has been developed for hepatitis C virus (HCV) NS3 protease using the scintillation proximity assay (SPA) technology. The sequence of the peptide substrate used was taken from the site cleaved by the enzyme in the mature nonstructur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560ba9f1795d801fd2fe398bacf5702e
https://pubmed.ncbi.nlm.nih.gov/10894758
https://pubmed.ncbi.nlm.nih.gov/10894758
Publikováno v:
Epilepsia. 41(S1)
Summary: Purpose: This study was undertaken to test the hypothesis that topiramate (TPM) exerts a negative modulatory effect on some types of a-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid (AMPA)/kainate receptors by binding to the site at whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8797aef034512d6f4f10186f8596cc
https://pubmed.ncbi.nlm.nih.gov/10768301
https://pubmed.ncbi.nlm.nih.gov/10768301
Autor:
Adrian Cushing, Alison J Harris, Molly J. Price-Jones, Kelvin T. Hughes, Robert Graves, David M. Lodge, David Bleakman
Publikováno v:
Journal of neuroscience methods. 90(1)
Human embryonic kidney cells (HEK293), expressing the human GluR4 receptor sub-unit of 2-amino-3-hydroxy-methylisoxazol-4-ylpropionic acid (AMPA) type non-NMDA receptors were used, in combination with Cytostar-T ™ scintillating microplates, to deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea615c612735e3be34a94aaf394a22cf
https://pubmed.ncbi.nlm.nih.gov/10517271
https://pubmed.ncbi.nlm.nih.gov/10517271
Autor:
Molly J. Price-Jones, John L. Harwood
Publikováno v:
Biochemical Journal. 216:627-631
Indol-3-ylacetic acid stimulated stem elongation within 1 h of treatment of Pisum sativum L. cv. Feltham First stem sections. This elongation was accompanied by an increase in the endogenous level of phosphocholine and a decrease in that of CDP-choli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7cb98edaf8b5930ba3320feb9bc13ac
https://doi.org/10.1042/bj2160627
https://doi.org/10.1042/bj2160627
Autor:
Molly J. Price-Jones, John L. Harwood
Publikováno v:
Phytochemistry. 24:2523-2527
CTP:cholinephosphate cytidylyltransferase (EC 2.7.7.15) was purified from pea ( Pisum sativum ) stems. The purification involved ammonium sulphate fractionation, ion exchange chromatography, removal of proteases with α 2 -macroglobulin and gel filtr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::854deae0426da4019950eae63f19d16e
https://doi.org/10.1016/s0031-9422(00)80660-3
https://doi.org/10.1016/s0031-9422(00)80660-3
Publikováno v:
Phytochemistry. 22:2421-2425
Indole-3-acetic acid (IAA) was found to stimulate stem elongation but inhibit the incorporation of [ 14 C]choline into phosphatidylcholine within 1 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::121ec2bbebebde3ea8bf16cf286bc0b9
https://doi.org/10.1016/0031-9422(83)80132-0
https://doi.org/10.1016/0031-9422(83)80132-0
Autor:
John L. Harwood, Molly J. Price-Jones
Publikováno v:
Phytochemistry. 26:81-83
Indole-3-acetic (IAA) reduced the activity of CTP:cholinephosphate cytidylyltransferase in pea (Pisum sativum) stems by an average of 45% compared to controls 1 hr after treatment. An enzyme-linked immunosorbent assay (ELISA) was developed to measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc68aba59a476166709466d10d0f132
https://doi.org/10.1016/s0031-9422(00)81485-5
https://doi.org/10.1016/s0031-9422(00)81485-5