Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Molly Gordon"'
Autor:
Xianrong Wong, Victoria E. Hoskins, Ashley J. Melendez-Perez, Jennifer C. Harr, Molly Gordon, Karen L. Reddy
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract Background The dynamic 3D organization of the genome is central to gene regulation and development. The nuclear lamina influences genome organization through the tethering of lamina-associated domains (LADs) to the nuclear periphery. Evidenc
Externí odkaz:
https://doaj.org/article/c3c02a39c176426f994be672983a5aeb
Autor:
Karen L. Reddy, Xianrong Wong, Jennifer C. Harr, Ashley J. Melendez-Perez, Victoria E. Hoskins, Molly Gordon
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Genome Biology
Genome Biology
Background The dynamic 3D organization of the genome is central to gene regulation and development. The nuclear lamina influences genome organization through the tethering of lamina-associated domains (LADs) to the nuclear periphery. Evidence suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d727b702f44b0eca5731eba60b49cb8
https://doaj.org/article/c3c02a39c176426f994be672983a5aeb
https://doaj.org/article/c3c02a39c176426f994be672983a5aeb
Autor:
Alexandra Selivanova, Rong Li, Roded Sharan, Shir Klein-Lavi, Mareike Herzog, Jin Zhu, Iñigo Ayestaran, Israel Salguero, Stephen P. Jackson, Siyue Wang, Martin Kupiec, Roi Meirman, Molly Gordon, Gonzalo Millán-Zambrano, Fabio Puddu
Publikováno v:
Nature. 573:416-420
Despite major progress in defining the functional roles of genes, a complete understanding of their influences is far from being realized, even in relatively simple organisms. A major milestone in this direction arose via the completion of the yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::090eae16b2265900cde70e616889149e
https://doi.org/10.1038/s41586-019-1549-9
https://doi.org/10.1038/s41586-019-1549-9
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 11, Iss 5 (2021)
G3: Genes, Genomes, Genetics, Vol 11, Iss 5 (2021)
To maintain genome stability, organisms depend on faithful chromosome segregation, a process affected by diverse genetic pathways, some of which are not directly linked to mitosis. In this study, we set out to explore one such pathway represented by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c804577e05bdccf2ee6359a19c2d5e
https://doi.org/10.1093/g3journal/jkab084
https://doi.org/10.1093/g3journal/jkab084
Autor:
Jevon Cutler, Xianrong Wong, Karen L. Reddy, Anil K. Madugundu, Molly Gordon, Akhilesh Pandey, Victoria E. Hoskins
Publikováno v:
Life Science Alliance
The nuclear lamina provides structure to the nucleus and serves as an interface between the cytoskeleton and large heterochromatin domains called LADs. This study describes the microproteome of this LAD/lamina interface.
The nuclear lamina is a
The nuclear lamina is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a47c246418ecb8b3042d96ccdedcc84
http://europepmc.org/articles/PMC8008952
http://europepmc.org/articles/PMC8008952
The dynamic 3D organization of the genome is central to the regulation of gene expression and developmental progression, with its disruption being implicated in various diseases. The nuclear lamina, a proteinaceous meshwork underlying the nuclear env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3beeb82485b3e4461161eb34d0b57ae1
https://doi.org/10.1101/2020.07.28.213884
https://doi.org/10.1101/2020.07.28.213884
Autor:
Anil K. Madugundu, Victoria E. Hoskins, Molly Gordon, Akhilesh Pandey, Karen L. Reddy, Jevon Cutler, Xianrong Wong
The nuclear lamina is a proteinaceous network of filaments that provide both structural and gene regulatory functions by tethering proteins and large domains of DNA, so-called lamin associated domains (LADs), to the periphery of the nucleus. LADs are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f6eb88923775d3a784d1e47a0fdf23
https://doi.org/10.1101/828210
https://doi.org/10.1101/828210
Aneuploidy, chromosome stoichiometry that deviates from exact multiples of the haploid compliment of an organism, exists in eukaryotic microbes, several normal human tissues, and the majority of solid tumors. Here, we review the current understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900cfd0b247c0e77d5ed176847ba935a
https://europepmc.org/articles/PMC6529225/
https://europepmc.org/articles/PMC6529225/
Autor:
Sue Escobar, Ahmet Ay, Kerri Woods, Kriti Jain, Soo Bin Kwon, Allan Filipowicz, Krista K. Ingram, Molly Gordon, Isaac H. Smith, Neil Bearden
Publikováno v:
Scientific Reports
Recent reports highlight that human decision-making is influenced by the time of day and whether one is a morning or evening person (i.e., chronotype). Here, we test whether these behavioral effects are associated with endogenous biological rhythms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aef9de54e1bb5c24429fcd8b426881c
https://doi.org/10.1038/srep29392
https://doi.org/10.1038/srep29392
Autor:
Molly Gordon, Raphael Salles Scortegagna de Medeiros, Raj Murali, Anubhav G. Amin, Nelci Zanon, Meena Jhanwar-Uniyal, Samuel Gelnick
Publikováno v:
Cancer Research. 77:3118-3118
Medulloblastoma (MB) is the most common primary pediatric malignant brain tumor. Genetic classification and distinct histologic subtypes defines MB into 4 groups: classic (WNT), sonic hedgehog (Shh), group 3 and group 4. In addition, recent studies h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6849df5be396ceef69b6fe6f08341ab6
https://doi.org/10.1158/1538-7445.am2017-3118
https://doi.org/10.1158/1538-7445.am2017-3118