Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Molly Fitzgerald-Hayes"'
Publikováno v:
Proceedings of the National Academy of Sciences. 104:10571-10576
A universal mark of centromeric chromatin is its packaging by a variant of histone H3 known as centromeric H3 (CenH3). The mechanism by which CenH3s are incorporated specifically into centromere DNA or the specialized function they serve there is not
Autor:
Kendra Harris, Richard Baker, Kevin C. Keith, Sam Stoler, Yinhuai Chen, Molly Fitzgerald-Hayes
Publikováno v:
Molecular and Cellular Biology. 19:6130-6139
The nucleosome core is composed of an evolutionarily conserved octamer of four core histone proteins, H2A, H2B, H3, and H4, and 145 to 147 bp of DNA (26). Histone-histone and histone-DNA interactions that form the core nucleosome are mediated through
Publikováno v:
Genes & Development. 9:573-586
The centromere, a differentiated region of the eukaryotic chromosome, mediates the segregation of sister chromatids at mitosis. In this study, a Saccharomyces cerevisiae chromosome mis-segregation mutant, cse4-1, has been isolated and shown to increa
Publikováno v:
Molecular and Cellular Biology. 13:4691-4702
By monitoring the mitotic transmission of a marked chromosome bearing a defective centromere, we have identified conditional alleles of two genes involved in chromosome segregation (cse). Mutations in CSE1 and CSE2 have a greater effect on the segreg
Autor:
W E Payne, Molly Fitzgerald-Hayes
Publikováno v:
Molecular and Cellular Biology. 13:4351-4364
We identified a putative Saccharomyces cerevisiae homolog of a phosphoinositide-specific phospholipase C (PI-PLC) gene, PLC1, which encodes a protein most similar to the delta class of PI-PLC enzymes. The PLC1 gene was isolated during a study of yeas
Publikováno v:
Molecular and Cellular Biology. 11:154-165
We have used in vivo genomic footprinting to investigate the protein-DNA interactions within the conserved DNA elements (CDEI, CDEII, and CDEIII) in the centromere from chromosome III of the yeast Saccharomyces cerevisiae. The in vivo footprint patte
Publikováno v:
Chromosoma. 101:189-197
We constructed Saccharomyces cerevisiae centromere DNA mutants by annealing and ligating synthetic oligonucleotides, a novel approach to centromere DNA mutagenesis that allowed us to change only one structural parameter at a time. Using this method,
Appropriate for a wide range of disciplines, from biology to non-biology, law and nursing majors, DNA and Biotechnology uses a straightforward and comprehensive writing style that gives the educated layperson a survey of DNA by presenting a brief his
Centromere-specific H3-like proteins (CenH3s) are conserved across the eukaryotic kingdom and are required for packaging centromere DNA into a specialized chromatin structure required for kinetochore assembly. Cse4 is the CenH3 protein of the budding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb044371a6797e99e3d01e22a106eaf6
https://europepmc.org/articles/PMC539035/
https://europepmc.org/articles/PMC539035/
Autor:
Kevin C. Keith, Molly Fitzgerald-Hayes
Each Saccharomyces cerevisiae chromosome contains a single centromere composed of three conserved DNA elements, CDE I, II, and III. The histone H3 variant, Cse4p, is an essential component of the S. cerevisiae centromere and is thought to replace H3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19269cdd9f8e63bcb2ced07368563c8
https://europepmc.org/articles/PMC1461345/
https://europepmc.org/articles/PMC1461345/