Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Molly E Johnson"'
Autor:
Bilge E Öztürk, Molly E Johnson, Michael Kleyman, Serhan Turunç, Jing He, Sara Jabalameli, Zhouhuan Xi, Meike Visel, Valérie L Dufour, Simone Iwabe, Luis Felipe L Pompeo Marinho, Gustavo D Aguirre, José-Alain Sahel, David V Schaffer, Andreas R Pfenning, John G Flannery, William A Beltran, William R Stauffer, Leah C Byrne
Publikováno v:
eLife, Vol 10 (2021)
Background: Adeno-associated virus (AAV)-mediated gene therapies are rapidly advancing to the clinic, and AAV engineering has resulted in vectors with increased ability to deliver therapeutic genes. Although the choice of vector is critical, quantita
Externí odkaz:
https://doaj.org/article/2f839da7c7b643a2acc12975971ae2e2
Autor:
Zhouhuan Xi, Bilge E. Öztürk, Molly E. Johnson, Serhan Turunç, William R. Stauffer, Leah C. Byrne
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 476-489 (2022)
Gene therapy is a rapidly developing field, and adeno-associated viruses (AAVs) are a leading viral-vector candidate for therapeutic gene delivery. Newly engineered AAVs with improved abilities are now entering the clinic. It has proven challenging,
Externí odkaz:
https://doaj.org/article/0b6055e7153143f08ae34481985f349e
Publikováno v:
Molecular Therapy - Methods & Clinical Development. 25:476-489
Gene therapy is a rapidly developing field, and adeno-associated virus (AAV) is a leading viral vector candidate for therapeutic gene delivery. Newly engineered AAVs with improved abilities are now entering the clinic. It has proven challenging, howe
Publikováno v:
mSphere, Vol 3, Iss 1 (2018)
ABSTRACT Human papillomavirus (HPV) is present in a subset of head and neck squamous cell carcinomas (HNSCCs). The cell cycle regulatory Rb-E2F pathway is a major target of HPV and is perturbed by these viruses in cell culture and animal models, as w
Externí odkaz:
https://doaj.org/article/752ceb14175942038fad28125169bbb8
Autor:
Zhouhuan Xi, José-Alain Sahel, Simone Iwabe, Gustavo D. Aguirre, Michael Kleyman, Serhan Turunç, Luis Felipe Marinho, Meike Visel, Andreas R. Pfenning, Jing He, William A. Beltran, Valerie L. Dufour, William R. Stauffer, John G. Flannery, Molly E. Johnson, Bilge Esin Ozturk, David V. Schaffer, Sara Jabalameli, Leah C. Byrne
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Background: Adeno-associated virus (AAV)-mediated gene therapies are rapidly advancing to the clinic, and AAV engineering has resulted in vectors with increased ability to deliver therapeutic genes. Although the choice of vector is critical, quantita
Autor:
Anne-Kathrin Emde, André Corvelo, Carissa A. Sanchez, Minita Shah, Lucian P. Smith, Benjamin Hubert, Carlo C. Maley, Xiaotong Yao, Rashesh Sanghvi, Elisa Venturini, Xiaohong Li, Nicolas Robine, Marcin Imielinski, Jennifer M. G. Shelton, Mary K. Kuhner, Kevin Hadi, Thomas G. Paulson, Kanika Arora, Molly E. Johnson, Brian J. Reid, Kenji Oman, Patricia C. Galipeau
While the genomes of normal tissues undergo dynamic changes over time, little is understood about the temporal-spatial dynamics of genomes in premalignant tissues that progress to cancer compared to those that remain cancer-free. Here we use whole ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2a6ee14aed9bb0ef0de0ce3c5cdbaf9
https://doi.org/10.21203/rs.3.rs-257949/v1
https://doi.org/10.21203/rs.3.rs-257949/v1
Autor:
Andreas R. Pfenning, John G. Flannery, David V. Schaffer, Zhouhuan Xi, Leah C. Byrne, Gustavo D. Aguirre, Molly E. Johnson, Meike Visel, José-Alain Sahel, Serhan Turunç, Bilge Esin Ozturk, Jing He, William A. Beltran, William R. Stauffer, Michael Kleyman, Sara Jabalameli, Simone Iwabe, Felipe Pompeo Marinho, Valerie L. Dufour
Adeno-associated virus (AAV)-mediated gene therapies are rapidly advancing to the clinic, and AAV engineering has resulted in vectors with increased ability to deliver therapeutic genes. Although the choice of vector is critical, quantitative compari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7469792bd0a16adb9b59cb0588275564
https://doi.org/10.1101/2020.10.01.323196
https://doi.org/10.1101/2020.10.01.323196
Autor:
Vaidehi Jobanputra, Rashesh Sanghvi, Molly E. Johnson, Dayna M. Oschwald, Minita Shah, Nicolas Robine, Jennifer M. G. Shelton, Michael C. Zody, Kanika Arora, Jade Carter, Soren Germer, Kshithija Nagulapalli
To test the performance of a new sequencing platform, develop an updated somatic calling pipeline and establish a reference for future benchmarking experiments, we sequenced 3 common cancer cell lines along with their matched normal cell lines to gre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f10a570273e6997ccf22f287ee2a673
https://doi.org/10.1101/623702
https://doi.org/10.1101/623702