Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Molly Chilton"'
Autor:
Michael D Healy, Manuela K Hospenthal, Ryan J Hall, Mintu Chandra, Molly Chilton, Vikas Tillu, Kai-En Chen, Dion J Celligoi, Fiona J McDonald, Peter J Cullen, J Shaun Lott, Brett M Collins, Rajesh Ghai
Publikováno v:
eLife, Vol 7 (2018)
The COMMD proteins are a conserved family of proteins with central roles in intracellular membrane trafficking and transcription. They form oligomeric complexes with each other and act as components of a larger assembly called the CCC complex, which
Externí odkaz:
https://doaj.org/article/52ef44e3fdd642e78e446da5ae0c2ac6
Autor:
Michael D. Healy, Kerrie E. McNally, Rebeka Butkovic, Molly Chilton, Kohji Kato, Joanna Sacharz, Calum McConville, Edmund R.R. Moody, Shrestha Shaw, Vicente J. Planelles-Herrero, Sathish K.N. Yadav, Jennifer Ross, Ufuk Borucu, Catherine S. Palmer, Kai-En Chen, Tristan I. Croll, Ryan J. Hall, Nikeisha J. Caruana, Rajesh Ghai, Thi H.D. Nguyen, Kate J. Heesom, Shinji Saitoh, Imre Berger, Christiane Schaffitzel, Tom A. Williams, David A. Stroud, Emmanuel Derivery, Brett M. Collins, Peter J. Cullen
SUMMARYThe Commander complex is required for endosomal recycling of diverse transmembrane cargos and is mutated in Ritscher-Schinzel syndrome. It comprises two subassemblies; Retriever composed of VPS35L, VPS26C and VPS29, and the CCC complex which c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d210a5342199c943249b9d1af8c0d6
https://doi.org/10.2139/ssrn.4330804
https://doi.org/10.2139/ssrn.4330804
Autor:
Michael D. Healy, Kerrie E. McNally, Rebeka Butkovič, Molly Chilton, Kohji Kato, Joanna Sacharz, Calum McConville, Edmund R.R. Moody, Shrestha Shaw, Vicente J. Planelles-Herrero, Sathish K.N. Yadav, Jennifer Ross, Ufuk Borucu, Catherine S. Palmer, Kai-En Chen, Tristan I. Croll, Ryan J. Hall, Nikeisha J. Caruana, Rajesh Ghai, Thi H.D. Nguyen, Kate J. Heesom, Shinji Saitoh, Imre Berger, Christiane Schaffitzel, Tom A. Williams, David A. Stroud, Emmanuel Derivery, Brett M. Collins, Peter J. Cullen
Publikováno v:
Cell. 186:2219-2237.e29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::001a432f260a60ee9ee88d785a8ef286
https://doi.org/10.1016/j.cell.2023.04.003
https://doi.org/10.1016/j.cell.2023.04.003
Autor:
Michael D. Healy, Joanna Sacharz, Kerrie E. McNally, Calum McConville, Vikas A. Tillu, Ryan J. Hall, Molly Chilton, Peter J. Cullen, Mehdi Mobli, Rajesh Ghai, David A. Stroud, Brett M. Collins
Publikováno v:
Structure. 30:1590-1602.e6
The sorting nexin SNX17 controls endosomal recycling of transmembrane cargo proteins including integrins, the amyloid precursor protein, and lipoprotein receptors. This requires association with the Commander trafficking complex and depends on the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da78120e050f253f56748e205b31898
https://doi.org/10.1016/j.str.2022.10.001
https://doi.org/10.1016/j.str.2022.10.001
Autor:
David A. Stroud, Rajesh Ghai, Michael D. Healy, Calum McConville, Molly Chilton, Ryan J. Hall, Joanna Sacharz, Brett M. Collins, Mehdi Mobli, Peter J. Cullen, Kerrie E. McNally
The sorting nexin SNX17 controls endosome-to-cell surface recycling of diverse transmembrane cargo proteins including integrins, the amyloid precursor protein and lipoprotein receptors. This requires association with the multi-subunit Commander traff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e13ee45c517c3e54b7f048b8a1f4847
https://doi.org/10.1101/2021.07.29.454387
https://doi.org/10.1101/2021.07.29.454387
Autor:
Joanna Sacharz, Ryan J. Hall, Mehdi Mobli, Brett M. Collins, Rajesh Ghai, Peter J. Cullen, Michael D. Healy, Calum McConville, David A. Stroud, Molly Chilton, Kerrie E. McNally
Publikováno v:
SSRN Electronic Journal.
The sorting nexin SNX17 controls endosome-to-cell surface recycling of diverse transmembrane cargo proteins including integrins, the amyloid precursor protein and lipoprotein receptors. This requires association with the multi-subunit Commander traff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc9fa0ea90173eacb58288275edce095
https://doi.org/10.2139/ssrn.3932601
https://doi.org/10.2139/ssrn.3932601
Publikováno v:
Journal of Medicinal Chemistry. 60:4923-4931
Evaluating the ligandability of a protein target is a key component when defining hit-finding strategies or when prioritize among drug targets. Computational as well as biophysical approaches based on nuclear magnetic resonance (NMR) fragment screeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ecb8050938cb4cebd12b1156a1eec95
https://doi.org/10.1021/acs.jmedchem.7b00208
https://doi.org/10.1021/acs.jmedchem.7b00208
Autor:
Molly Chilton, Mintu Chandra, Vikas A. Tillu, Peter J. Cullen, Manuela K. Hospenthal, Ryan J. Hall, Dion J. Celligoi, Fiona J. McDonald, J. Shaun Lott, Rajesh Ghai, Brett M. Collins, Kai-En Chen, Michael D. Healy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efd2cab46142869e7dae30670350cc54
https://doi.org/10.7554/elife.35898.032
https://doi.org/10.7554/elife.35898.032