Výsledky vyhledávání - "Molly C, Holbrook"

Akademický článek

Acquired chemoresistance can lead to increased resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus

Autor: Dakota W. Goad, Christian Bressy, Molly C. Holbrook, Valery Z. Grdzelishvili

Publikováno v: Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 59-76 (2022)

Vesicular stomatitis virus (VSV) is a promising oncolytic virus (OV) against different malignancies, including pancreatic ductal adenocarcinoma (PDAC). Our previous studies have demonstrated that VSV-based OVs are effective against the majority of te

Externí odkaz: https://doaj.org/article/a7b2a4a0007042c1af93ae75f8eabf0b

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Acquired chemoresistance can lead to increased resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus

Autor: Dakota W. Goad, Christian Bressy, Molly C. Holbrook, Valery Z. Grdzelishvili

Publikováno v: Molecular Therapy Oncolytics
Molecular Therapy: Oncolytics, Vol 24, Iss, Pp 59-76 (2022)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280695de3bfbbf66104e595995253dcd
https://pubmed.ncbi.nlm.nih.gov/34977342

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Expanding the Spectrum of Pancreatic Cancers Responsive to Vesicular Stomatitis Virus-Based Oncolytic Virotherapy: Challenges and Solutions

Autor: Valery Z. Grdzelishvili, Dakota W Goad, Molly C Holbrook

Publikováno v: Cancers, Vol 13, Iss 1171, p 1171 (2021)
Cancers

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy with a poor prognosis and a dismal survival rate. Oncolytic virus (OV) is an anticancer approach that utilizes replication-competent viruses to preferentially infect a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb4fc4f793e17fe63d98a0bd5fc3e21
https://www.mdpi.com/2072-6694/13/5/1171

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YML018C protein localizes to the vacuolar membrane independently of Atg27p

Autor: Candyce M, Sturgeon, Nicholas, Zanghi, Hannah M, Smith, Emily K, Davis, Meaghan R, Robinson, Elizabeth, Cabrera, Molly C, Holbrook, Verónica A, Segarra

Large-scale studies have localized the uncharacterized YML018C protein to the vacuolar membrane and have identified the autophagy-related protein Atg27p as one of its 10 physical interactors (Huh et al., 2003; Tarasov et al., 2008). These two finding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52293f93bbbbed6b291fedd4c8aa462