Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Molly B El Alam"'
Autor:
Kyoko Yoshida-Court, Tatiana V Karpinets, Aparna Mitra, Travis N Solley, Stephanie Dorta-Estremera, Travis T Sims, Andrea Y Delgado Medrano, Molly B El Alam, Mustapha Ahmed-Kaddar, Erica J Lynn, K Jagannadha Sastry, Jianhua Zhang, Andrew Futreal, Alpa Nick, Karen Lu, Lauren E Colbert, Ann H Klopp
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0279590 (2023)
We evaluated the association of disease outcome with T cell immune-related characteristics and T cell receptor (TCR) repertoire in malignant ascites from patients with high-grade epithelial ovarian cancer. Ascitic fluid samples were collected from 47
Externí odkaz:
https://doaj.org/article/5a0b5608e53749508f08e2b79b859a7d
Autor:
Molly B El Alam, Travis T Sims, Ramez Kouzy, Greyson W G Biegert, Joseph A B I Jaoude, Tatiana V Karpinets, Kyoko Yoshida-Court, Xiaogang Wu, Andrea Y Delgado-Medrano, Melissa P Mezzari, Nadim J Ajami, Travis Solley, Mustapha Ahmed-Kaddar, Lilie L Lin, Lois Ramondetta, Amir Jazaeri, Anuja Jhingran, Patricia J Eifel, Kathleen M Schmeler, Jennifer Wargo, Ann H Klopp, Lauren E Colbert
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247905 (2021)
BackgroundA diverse and abundant gut microbiome can improve cancer patients' treatment response; however, the effect of pelvic chemoradiotherapy (CRT) on gut diversity and composition is unclear. The purpose of this prospective study was to identify
Externí odkaz:
https://doaj.org/article/db475cc6a3564be6882ba4c6c43e00ea
Autor:
Tatiana V. Karpinets, Xiaogang Wu, Travis Solley, Molly B. El Alam, Travis T. Sims, Kyoko Yoshida-Court, Erica Lynn, Mustapha Ahmed-Kaddar, Greyson Biegert, Jingyan Yue, Xingzhi Song, Huandong Sun, Joseph F. Petrosino, Melissa P. Mezzari, Pablo Okhuysen, Patricia J. Eifel, Anuja Jhingran, Lilie L. Lin, Kathleen M. Schmeler, Lois Ramondetta, Nadim Ajami, Robert R. Jenq, Andrew Futreal, Jianhua Zhang, Ann H. Klopp, Lauren E. Colbert
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background Gut microbiome community composition differs between cervical cancer (CC) patients and healthy controls, and increased gut diversity is associated with improved outcomes after treatment. We proposed that functions of specific micr
Externí odkaz:
https://doaj.org/article/0aaae9f1b6404c15b3d264ad029b00a4
Autor:
Travis T. Sims, Molly B. El Alam, Tatiana V. Karpinets, Stephanie Dorta-Estremera, Venkatesh L. Hegde, Sita Nookala, Kyoko Yoshida-Court, Xiaogang Wu, Greyson W. G. Biegert, Andrea Y. Delgado Medrano, Travis Solley, Mustapha Ahmed-Kaddar, Bhavana V. Chapman, K. Jagannadha Sastry, Melissa P. Mezzari, Joseph F. Petrosino, Lilie L. Lin, Lois Ramondetta, Anuja Jhingran, Kathleen M. Schmeler, Nadim J. Ajami, Jennifer Wargo, Lauren E. Colbert, Ann H. Klopp
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Travis Sims and Molly El Alam et al. show that diversity of gut microbiota is associated with a favorable response to chemoradiation for cervical cancer and use flow cytometry to show that patients with high microbiome diversity had increased tumor i
Externí odkaz:
https://doaj.org/article/c76ee253ea0f4e5b85dab20f72cbe758
Autor:
Daniel Lin, Molly B. El Alam, Joseph Abi Jaoude, Ramez Kouzy, Jae L. Phan, Jacob H. Elnaggar, Brianna Resendiz, Andrea Y. Delgado Medrano, Erica J. Lynn, Nicholas D. Nguyen, Sonal S. Noticewala, Geena G. Mathew, Emma B. Holliday, Bruce D. Minsky, Prajnan Das, Van K. Morris, Cathy Eng, Melissa P. Mezzari, Joseph F. Petrosino, Nadim J. Ajami, Ann H. Klopp, Cullen M. Taniguchi, Lauren E. Colbert
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 113:974-984
Patients with localized squamous cell carcinoma of the anus (SCCA) who experience treatment toxicity or recurrences have few therapeutic options. Investigation into the microbiome's influence on treatment toxicity and its potential use as a predictiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5d566515232844e127d95c4eb7aff1
https://doi.org/10.1016/j.ijrobp.2022.04.037
https://doi.org/10.1016/j.ijrobp.2022.04.037
Autor:
Jacob H. Elnaggar, Victoria O. Huynh, Daniel Lin, R. Tyler Hillman, Chike O. Abana, Molly B. El Alam, Katarina C. Tomasic, Tatiana V. Karpinets, Ramez Kouzy, Jae L. Phan, Jennifer Wargo, Emma B. Holliday, Prajnan Das, Melissa P. Mezzari, Nadim J. Ajami, Erica J. Lynn, Bruce D. Minsky, Van K. Morris, Andrea Milbourne, Craig A. Messick, Ann H. Klopp, P. Andrew Futreal, Cullen M. Taniguchi, Kathleen M. Schmeler, Lauren E. Colbert
Publikováno v:
Frontiers in Immunology. 14
BackgroundSquamous cell carcinoma of the anus (SCCA) is a rare gastrointestinal cancer. Factors associated with progression of HPV infection to anal dysplasia and cancer are unclear and screening guidelines and approaches for anal dysplasia are less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89ffe1fc6d67c4178166dd60ac6b3189
https://doi.org/10.3389/fimmu.2023.1051431
https://doi.org/10.3389/fimmu.2023.1051431
Autor:
Julie Sammouri, Matthew C. Wong, Erica J. Lynn, Molly B. El Alam, David K. Lo, Daniel Lin, Timothy H. Harris, Tatiana V. Karpinets, Kyoko Court, Tatiana Cisneros Napravnik, Xiaogang Wu, Jianhua Zhang, Ann H. Klopp, Nadim J. Ajami, Lauren E. Colbert
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4131308da4a42c782e766ef2855d9e0f
https://doi.org/10.1016/j.ijrobp.2023.02.018
https://doi.org/10.1016/j.ijrobp.2023.02.018
Cervicovaginal microbiota profiles in precancerous lesions and cervical cancer among Ethiopian women
Autor:
Brhanu Teka, Kyoko Yoshida-Court, Ededia Firdawoke, Zewditu Chanyalew, Muluken Gizaw, Adamu Addissie, Adane Mihret, Lauren E. Colbert, Tatiana Cisneros Napravnik, Molly B. El Alam, Erica J. Lynn, Melissa Mezzari, Jhingran Anuja, Eva Johanna Kantelhardt, Andreas M. Kaufmann, Ann H. Klopp, Tamrat Abebe
Publikováno v:
Microorganisms; Volume 11; Issue 4; Pages: 833
Although high-risk human papillomavirus infection is a well-established risk factor for cervical cancer, other co-factors within the local microenvironment may play an important role in the development of cervical cancer. The current study aimed to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dbb0c8d1ac211acd7f6d903fab33412
Autor:
Kyoko Yoshida-Court, Tatiana V. Karpinets, Aparna Mitra, Travis N. Solley, Stephanie Dorta-Estremera, Travis T. Sims, Andrea Y. Delgado Medrano, Molly B. El Alam, Mustapha Ahmed-Kaddar, Erica J. Lynn, K. Jagannadha Sastry, Jianhua Zhang, Andrew Futreal, Alpa Nick, Karen Lu, Lauren E. Colbert, Ann H. Klopp
Publikováno v:
PloS one. 18(1)
We evaluated the association of disease outcome with T cell immune-related characteristics and T cell receptor (TCR) repertoire in malignant ascites from patients with high-grade epithelial ovarian cancer. Ascitic fluid samples were collected from 47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6a0b2ad035d1da9712031bb52ceef0
https://pubmed.ncbi.nlm.nih.gov/36607962
https://pubmed.ncbi.nlm.nih.gov/36607962
Autor:
Lauren E. Colbert, Tatiana Karpinets, Molly B. El Alam, Erica J. Lynn, Julie Sammouri, David Lo, Jacob H Elnaggar, Rui Wang, Timothy A Harris, Kyoko Yoshida-Court, Katarina Tomasic, Julianna K. Bronk, Ananta V. Yanamandra, Adilene V. Olvera, Lily G. Carlin, Travis Sims, Andrea Y. Delgado Medrano, Travis Solley, Patricia J. Eifel, Anuja Jhingran, Melissa Joyner, Lilie Lin, Lois M. Ramondetta, Andrew M. Futreal, Kathleen M. Schmeler, Geena Mathew, Stephanie Dorta-Estremera, Jianhua Zhang, Xiaogang Wu, Nadim J. Ajami, Cullen Taniguchi, Joseph F. Petrosino, Jennifer Wargo, K. Jagannadha Sastry, Pablo C. Okhuysen, Ann H. Klopp
SUMMARYThis study identifies a novel pathotype of cervical cancer-associated Lactobacillus iners (L. iners) that results in chemoradiation resistance in vitro and is associated with poor patient survival. Cervical cancer affects over half a million w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f47233bacb6f04b312145c8d07e2211
https://doi.org/10.1101/2022.04.26.22274346
https://doi.org/10.1101/2022.04.26.22274346