Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Molly A, Bassette"'
Autor:
Ran Wang, Sean Campbell, Mohammed Amir, Sarah A. Mosure, Molly A. Bassette, Amber Eliason, Mark S. Sundrud, Theodore M. Kamenecka, Laura A. Solt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Unlike RORα, which has been thought to be somewhat redundant, RORγt has been well characterized in its function and contribution to the development of Th17 cells. Here the authors show that RORα is important in Th17 differentiation and that RORα
Externí odkaz:
https://doaj.org/article/73087ff786264483a5b440dbda18a0f9
Autor:
Amber Eliason, Laura A. Solt, Ran Wang, Sarah A. Mosure, Sean Campbell, Mohammed Amir, Theodore M. Kamenecka, Mark S. Sundrud, Molly A. Bassette
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Full development of IL-17 producing CD4+ T helper cells (TH17 cells) requires the transcriptional activity of both orphan nuclear receptors RORα and RORγt. However, RORα is considered functionally redundant to RORγt; therefore, the function and t
Autor:
Anna N. Walker, Karrie Bulski, Patrick J. Geer, Richard F. Lee, Ashleigh R. Price, Shirley A. Powell, Molly A. Bassette, Stephen C. Landers, Marc E. Frischer, Michael C. Torris, Rufat Verdiyev, Tina L. Walters
Publikováno v:
Journal of Shellfish Research. 36:487-500
Penaeid shrimp including Litopenaeus setiferus (white shrimp), Farfantepenaeus aztecus (brown shrimp), and Farfantepenaeus duorarum (pink shrimp) support one of the most valuable commercial fisheries in the U.S. Southeast Atlantic. Since the late 199
Autor:
Ran, Wang, Sean, Campbell, Mohammed, Amir, Sarah A, Mosure, Molly A, Bassette, Amber, Eliason, Mark S, Sundrud, Theodore M, Kamenecka, Laura A, Solt
Publikováno v:
Nature Communications
Full development of IL-17 producing CD4+ T helper cells (TH17 cells) requires the transcriptional activity of both orphan nuclear receptors RORα and RORγt. However, RORα is considered functionally redundant to RORγt; therefore, the function and t
Autor:
Laura A Solt, Ran Wang, Mohammed Amir, Sweena Chaudhari, Sean Campbell, Molly B Bassette, Amber Eliason, Mark S Sundrud, Theodore Kamenecka
Publikováno v:
The Journal of Immunology. 202:68.11-68.11
While RORγt has been well characterized as the lineage defining transcription factor for TH17 cell development, TH17 cells are not absent in Rorc-deficient mice, suggesting other factors may be required. RORα, a close family member of RORγt, is al
Autor:
Laura A. Solt, Ran Wang, Mohammed Amir, Sweena M. Chaudhari, Sean Campbell, Molly A. Bassette, Theodore M. Kamenecka
Publikováno v:
The Journal of Immunology. 200:121.3-121.3
Dysregulated TH17 immune responses have been associated with the pathogenesis of several autoimmune diseases. While full development of TH17 cells requires both nuclear receptors RORα and RORγt, most of the work surrounding TH17 cells has focused o