Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mollisa M. Elrick"'
Autor:
Mollisa M. Elrick, Lauren M. Stein, John A. Corbett, Willis K. Samson, Grant R. Kolar, Gina L. C. Yosten, Alison S. Salvatori
Publikováno v:
Physiology & Behavior. 162:147-150
Insulin-dependent individuals with diabetes are at risk for a severe hypoglycemic event that may predispose them to several repeat episodes during which the normal counter regulatory mechanisms that protect against hypoglycemia fail to be activated.
Autor:
Gina L. C. Yosten, Aaron Naatz, John A. Corbett, Grant R. Kolar, Willis K. Samson, Alison S. Salvatori, Lauren M. Stein, Mollisa M. Elrick
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 310:R143-R155
Neuronostatin (NST) is a recently described peptide that is produced from the somatostatin preprohormone in pancreatic δ-cells. NST has been shown to increase glucagon secretion from primary rat pancreatic islets in low-glucose conditions. Here, we
Autor:
Stephanie M Knebel, Alan H. Stephenson, Amber K Zdanovec, Mary L. Ellsworth, Elizabeth A. Bowles, Randy S. Sprague, Mollisa M. Elrick
Publikováno v:
Experimental Biology and Medicine. 238:1069-1074
Prostacyclin (PGI2) and phosphodiesterase 5 (PDE5) inhibitors are potent vasodilators that are used alone and in combination for the treatment of pulmonary arterial hypertension (PAH). Although these vasodilators are known to stimulate relaxation of
Autor:
Richard A Mueller, Jennie L. Walgren, Mollisa M. Elrick, David C. Thompson, Dale L. Morris, Michael D. Mitchell
Publikováno v:
Chemical Research in Toxicology. 21:859-868
We describe a novel peptide-based in vitro method for the detection of reactive metabolites that is amenable for use with microsomal or purified enzyme systems. Covalently bound adducts are detected by mass spectrometry using a surface-enhanced laser
Autor:
Lauren M. Stein, Alison S. Salvatori, Gina L. C. Yosten, Grant R. Kolar, Mollisa M. Elrick, Jun Ren, John A. Corbett, Willis K. Samson
The Human Genome Project provided the opportunity to use bioinformatic approaches to discover novel, endogenous hormones. Using this approach we have identified two novel peptide hormones and review here our strategy for the identification and charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb1354f3ab1276415f332201510a44c
https://europepmc.org/articles/PMC4641813/
https://europepmc.org/articles/PMC4641813/
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 98:432-441
Interest in proteomics as a tool for drug development and a myriad of other applications continues to expand at a rapid rate. Proteomic analyses have recently been conducted on tissues, biofluids, subcellular components and enzymatic pathways as well
Autor:
Jeffrey A. Kramer, Larry D. Kier, Carl L. Alden, Eric A.G. Blomme, Sandra W. Curtiss, Roderick T. Bunch, Kyle L. Kolaja, Mollisa M. Elrick, Marc A. Cabonce, Charles P. Rodi, Dale L. Morris
Publikováno v:
Toxicologic Pathology. 33:118-126
Hepatic enzyme inducers such as phenobarbital are often nongenotoxic rodent hepatocarcinogens. Currently, nongenotoxic hepatocarcinogens can only be definitively identified through costly and extensive long-term, repeat-dose studies (e.g., 2-year rod
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 306(11)
Neuronostatin is a recently described peptide hormone encoded by the somatostatin gene. We previously showed that intraperitoneal injection of neuronostatin into mice resulted in c-Jun accumulation in pancreatic islets in a pattern consistent with th
Publikováno v:
The FASEB Journal. 28
Neuronostatin (NST) is produced in pancreatic delta cells from the somatostatin preprohormone, and has been shown to inhibit glucose-stimulated insulin secretion from beta cells of primary islets, but not from isolated beta cell cultures. We have dem
Autor:
Mary L. Ellsworth, Mollisa M. Elrick, Amber K Zdanovec, Elizabeth A. Bowles, Randy S. Sprague, Alan H. Stephenson
Publikováno v:
The FASEB Journal. 26