Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Mollie M Jurewicz"'
Autor:
Padma P. Nanaware, Mollie M. Jurewicz, Cristina C. Clement, Liying Lu, Laura Santambrogio, Lawrence J. Stern
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Antigen presentation by MHC-II proteins in the thymus is central to selection of CD4 T cells, but analysis of the full repertoire of presented peptides responsible for positive and negative selection is complicated by the low abundance of antigen pre
Externí odkaz:
https://doaj.org/article/6f7967e8c7d846e987bc706473261e3f
Autor:
Krista Daniel, Shrikanta Chattopadhyay, Kenneth N. Olivier, Alexandra Luther, Cisem Karaca, Gavin MacBeath, Yifan Wang, Livio Dukaj, Antoine Boudot, Amy Virbasius, Alexandra Cristofaro, Cagan Gurer, Andrew Basinski, Daniel Pollacksmith, Kenneth L Jahan, Qikai Xu, Danielle Ramsdell, Hannah L. Bader, Mollie M Jurewicz, Ribhu Nayar, Candace R. Perullo, Sida Liao, Kimberly M Cirelli, Lisa Nip, Sonal Jangalwe, Anna Labrozzi
Publikováno v:
Blood. 138:1704-1704
Background Approximately 50% of AML patients relapse following allogeneic hematopoietic stem cell transplant therapy, leaving them with very few treatment options (Rautenberg et al. (2019) Int. J. Mol. Sci. 20:228). Rare patients who naturally develo
Autor:
Lawrence Stern, Mollie M Jurewicz
Publikováno v:
The Journal of Immunology. 202:177.28-177.28
H2-O (DO) is a non-classical MHC-II protein thought to regulate antigen presentation through inhibition of the catalytic peptide exchange factor H2-M (DM). H2-O−/− (DO-KO) mice have reduced diversity in the MHC-II peptide repertoire presented by
Publikováno v:
The Journal of Immunology. 200:99.1-99.1
The classical MHC Class II molecules HLA-DP, DQ and DR proteins bind antigenic peptides in the endosomes of APCs and present them to CD4+ T cells whereas HLA-DM and DO are the non-classical proteins. DM catalyzes the exchange of CLIP peptides with ot
Publikováno v:
The Journal of Immunology. 200:99.22-99.22
Selection of CD4 T cells into the conventional and regulatory lineages is thought to be dependent on the strength of interaction of rearranged T cell receptors with MHCII-bound peptides displayed on APCs in the thymus. The nonclassical MHC molecule D
Autor:
Birtley JR; Department of Pathology, University of Massachusetts Medical School, Worcester, MA, 01655, USA.; UCB Pharma, Bath Road, Slough, SL1 3WE, UK., Alomary M; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0NN, UK., Zanini E; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0NN, UK., Antony J; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0NN, UK., Maben Z; Department of Pathology, University of Massachusetts Medical School, Worcester, MA, 01655, USA., Weaver GC; Department of Pathology, University of Massachusetts Medical School, Worcester, MA, 01655, USA., Von Arx C; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0NN, UK., Mura M; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0NN, UK., Marinho AT; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0NN, UK., Lu H; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0NN, UK., Morecroft EVN; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0NN, UK.; Department of Chemistry, Imperial College London, Wood Lane, London, W12 0BZ, UK., Karali E; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0NN, UK., Chayen NE; Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, SW7 2AZ, UK., Tate EW; Department of Chemistry, Imperial College London, Wood Lane, London, W12 0BZ, UK., Jurewicz M; Department of Pathology, University of Massachusetts Medical School, Worcester, MA, 01655, USA., Stern LJ; Department of Pathology, University of Massachusetts Medical School, Worcester, MA, 01655, USA. lawrence.stern@umassmed.edu., Recchi C; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0NN, UK. c.recchi@imperial.ac.uk., Gabra H; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Du Cane Road, London, W12 0NN, UK. h.gabra@imperial.ac.uk.; Clinical Discovery Unit, Early Clinical Development, IMED Biotech Unit, AstraZeneca, Cambridge, SG8 6HB, UK. h.gabra@imperial.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2019 Jul 17; Vol. 10 (1), pp. 3134. Date of Electronic Publication: 2019 Jul 17.
Autor:
Zandi-Nejad K; 2Division of Nephrology, 330 Brookline Ave., E/RN 304, Boston, MA 02215, USA. kzandi@bidmc.harvard.edu., Takakura A, Jurewicz M, Chandraker AK, Offermanns S, Mount D, Abdi R
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2013 Nov; Vol. 27 (11), pp. 4366-74. Date of Electronic Publication: 2013 Jul 23.
Autor:
Azzi J; Transplantation Research Center, Renal Division, Brigham and Women’s Hospital and Children’s Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA., Moore RF, Elyaman W, Mounayar M, El Haddad N, Yang S, Jurewicz M, Takakura A, Petrelli A, Fiorina P, Ruckle T, Abdi R
Publikováno v:
Diabetes [Diabetes] 2012 Jun; Vol. 61 (6), pp. 1509-18. Date of Electronic Publication: 2012 Mar 08.
Autor:
Fiorina P; Transplantation Research Center, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. paolo.fiorina@childrens.harvard.edu, Jurewicz M, Vergani A, Petrelli A, Carvello M, D'Addio F, Godwin JG, Law K, Wu E, Tian Z, Thoma G, Kovarik J, La Rosa S, Capella C, Rodig S, Zerwes HG, Sayegh MH, Abdi R
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2011 Jan 01; Vol. 186 (1), pp. 121-31. Date of Electronic Publication: 2010 Dec 03.
Autor:
Jurewicz M; Transplantation Research Center, Children's Hospital and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Yang S, Augello A, Godwin JG, Moore RF, Azzi J, Fiorina P, Atkinson M, Sayegh MH, Abdi R
Publikováno v:
Diabetes [Diabetes] 2010 Dec; Vol. 59 (12), pp. 3139-47. Date of Electronic Publication: 2010 Sep 14.