Energy Metabolism as a Therapeutic Target in Cancer: The Role of Coenzyme Q10

Autor: David Mantle, Hannah Rowbottom, Jacob Jones, Indiia Margarita Potts, Nadia Turton, Mollie Dewsbury, Guillermo Lopez-Lluch, Iain P. Hargreaves

Publikováno v: Oxygen, Vol 4, Iss 2, Pp 122-138 (2024)

The generation of energy within cells is a fundamental process enabling cell survival, and as such it represents a potential target in cancer therapy. In this article, we therefore review the relative contributions of glycolysis and oxidative phospho

Externí odkaz: https://doaj.org/article/6c463e37f37c417597df025ddee7652f

The Biochemical Assessment of Mitochondrial Respiratory Chain Disorders

Autor: Nadia Turton, Neve Cufflin, Mollie Dewsbury, Olivia Fitzpatrick, Rahida Islam, Lowidka Linares Watler, Cara McPartland, Sophie Whitelaw, Caitlin Connor, Charlotte Morris, Jason Fang, Ollie Gartland, Liv Holt, Iain P. Hargreaves

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 13, p 7487 (2022)

Mitochondrial respiratory chain (MRC) disorders are a complex group of diseases whose diagnosis requires a multidisciplinary approach in which the biochemical investigations play an important role. Initial investigations include metabolite analysis i

Externí odkaz: https://doaj.org/article/d08586576023487cb5e4e41ba01f0285

The Biochemical Assessment of Mitochondrial Respiratory Chain Disorders.

Autor: Turton, Nadia¹ (AUTHOR) n.m.turton@2020.ljmu.ac.uk, Cufflin, Neve¹ (AUTHOR), Dewsbury, Mollie¹ (AUTHOR), Fitzpatrick, Olivia¹ (AUTHOR), Islam, Rahida¹ (AUTHOR), Watler, Lowidka Linares¹ (AUTHOR), McPartland, Cara¹ (AUTHOR), Whitelaw, Sophie¹ (AUTHOR), Connor, Caitlin¹ (AUTHOR), Morris, Charlotte¹ (AUTHOR), Fang, Jason¹ (AUTHOR), Gartland, Ollie¹ (AUTHOR), Holt, Liv¹ (AUTHOR), Hargreaves, Iain P.¹ (AUTHOR) i.hargreaves@ucl.ac.uk

Publikováno v: International Journal of Molecular Sciences. Jul2022, Vol. 23 Issue 13, p7487-N.PAG. 13p.