Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mollie Daugherty"'
Autor:
Michelle Nelson, Robert Miller, Gabriele Blahnik-Fagan, Lauren Loh, Danielle Van Citters, Lynda Misher, Megan Sprague, Maria Dasovich, Irene Barber, Kathy Maggiora, Franz Gruswitz, Brian Woodruff, Kelsey Huntington, Aelish Guinn, Megan Aguilar, Mollie Daugherty, Elizabeth Haglin, Jane Gross, Peter Pavlik, Catherine McMahan, David Bienvenue, Gabriela Hernandez-Hoyos
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/6c64f973aedf40a3931e9470d8097583
Autor:
John W. Blankenship, Jane A. Gross, Sateesh K. Natarajan, Catherine J. McMahan, David Bienvenue, Paul A. Algate, Jennifer Wiens, Padma Ravikumar, Robert E. Miller, John Kumer, Rebecca Gottschalk, Hang Fang, Maria Dasovich, Mollie Daugherty, Ruth A. Chenault, Jeannette Bannink, Robert Bader, Toddy Sewell, Gabriela Hernandez-Hoyos
Phenotype of T-cells used in Xenograft Studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2753218e21d1867b3f4ecaeac3ac4a62
https://doi.org/10.1158/1535-7163.22503927
https://doi.org/10.1158/1535-7163.22503927
Autor:
John W. Blankenship, Jane A. Gross, Sateesh K. Natarajan, Catherine J. McMahan, David Bienvenue, Paul A. Algate, Jennifer Wiens, Padma Ravikumar, Robert E. Miller, John Kumer, Rebecca Gottschalk, Hang Fang, Maria Dasovich, Mollie Daugherty, Ruth A. Chenault, Jeannette Bannink, Robert Bader, Toddy Sewell, Gabriela Hernandez-Hoyos
Serum levels of human PSA from day 56 of the MDA-PCa-2b xenograft study (as shown in Figures 5C, 5D).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954a0027549be888c2d8fcab39e62449
https://doi.org/10.1158/1535-7163.22503936.v1
https://doi.org/10.1158/1535-7163.22503936.v1
Autor:
John W. Blankenship, Jane A. Gross, Sateesh K. Natarajan, Catherine J. McMahan, David Bienvenue, Paul A. Algate, Jennifer Wiens, Padma Ravikumar, Robert E. Miller, John Kumer, Rebecca Gottschalk, Hang Fang, Maria Dasovich, Mollie Daugherty, Ruth A. Chenault, Jeannette Bannink, Robert Bader, Toddy Sewell, Gabriela Hernandez-Hoyos
Supplementary Methods and Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595daef24c6b6d2a6523bafbb280afc5
https://doi.org/10.1158/1535-7163.22503933
https://doi.org/10.1158/1535-7163.22503933
Autor:
Elizabeth Haglin, Kelsey Huntington, Franz Gruswitz, Jane A. Gross, Gabriela Hernandez-Hoyos, Michelle H. Nelson, Megan Sprague, Lauren Loh, Gabriele Blahnik-Fagan, Catherine J. McMahan, Aelish Guinn, Megan Aguilar, Kathy Maggiora, Robert F. Miller, Peter Pavlik, Lynda Misher, Irene Barber, Maria M. Dasovich, Mollie Daugherty, Danielle Van Citters, David Bienvenue, Brian Woodruff
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background 4-1BB (CD137) and OX40 (CD134) are critical activation-induced co-stimulatory receptors that regulate immune responses of activated T and NK cells by enhancing proliferation, cytokine production, survival, and cytolytic activity. A superag
Autor:
Ruth A. Chenault, Jeannette Bannink, Hang Fang, Toddy Sewell, Catherine J. McMahan, John W. Blankenship, Robert R. Bader, David Bienvenue, Sateesh Kumar Natarajan, Paul A. Algate, Robert E. Miller, Jane A. Gross, Mollie Daugherty, Jennifer Wiens, Maria M. Dasovich, Gabriela Hernandez-Hoyos, John Kumer, Rebecca Gottschalk, Padma Ravikumar
Publikováno v:
Molecular Cancer Therapeutics. 15:2155-2165
Treatment of metastatic, castration-resistant prostate cancer (mCRPC) remains a highly unmet medical need and current therapies ultimately result in disease progression. Immunotherapy is a rapidly growing approach for treatment of cancer but has show
Autor:
Michael R. Comeau, Bannink Jeannette, Mollie Daugherty, David Jablonski, Lynda Misher, Catherine J. McMahan, David Bienvenue, Lara Parr, Rebecca Gottschalk, Gabriela H. Hoyos, Starrla Johnson, Toddy Sewell, Jane A. Gross, Melissa DeFrancesco, John Kumer
Publikováno v:
Cancer Research. 79:LB-199
Introduction: Depletion of CD123 over-expressing tumor cells may improve patient outcomes in several hematological malignancies including AML, MDS, ALL, CML, HCL and BPDCN. CD123 is infrequently expressed by normal cells making it an attractive tumor
Autor:
Robert E. Miller, David Bienvenue, Catherine J. McMahan, Toddy Sewell, Gabriela H. Hoyos, Jane A. Gross, Melissa DeFrancesco, Robert Bader, Lynda Misher, Lara Parr, Mollie Daugherty, Rebecca Gottschalk, Michael R. Comeau
Publikováno v:
Cancer Research. 78:1786-1786
Introduction: Depletion of CD123 over-expressing malignant cells provides a potential new treatment option which may improve patient outcomes in several hematological malignancies. CD123 is over-expressed in AML, MDS, ALL, CML, HCL and BPDCN and infr
Autor:
Maria M. Dasovich, Robert E. Miller, Michael R. Comeau, Peter Pavlik, Megan Aguilar, Gabriela H. Hoyos, Hang Fang, Danielle Mitchell, Starrla Johnson, Nicole Zhang, Jane A. Gross, Rebecca Gottschalk, Brian Woodruff, Mollie Daugherty, Gary Li, Lynda Misher, Catherine J. McMahan, John W. Blankenship, Jeannette Bannink, Robert Bader, Toddy Sewell, Lara Parr, David Bienvenue
Publikováno v:
Cancer Research. 77:597-597
Introduction: CD123 is a component of the IL-3 receptor expressed in several hematological malignancies including AML, ALL, HCL, and MDS. CD123 is a compelling target in AML due to its overexpression on AML blasts as well as leukemic stem cells, whic
Autor:
John W. Blankenship, Hang Fang, Megan Aguilar, Brian Woodruff, Mollie Daugherty, Nicole Zhang, Jeannette Bannink, Catherine J. McMahan, Padma Ravikumar, Robert E. Miller, Maria M. Dasovich, Lara Parr, Robert Bader, Carina Xu, Gabriela H. Hoyos, Jane A. Gross, Philip Tan, Lynda Misher, Danielle Mitchell, David Bienvenue
Publikováno v:
Cancer Research. 76:4995-4995
Background: Effective treatment of metastatic, triple-negative breast cancer (TNBC) remains a highly unmet medical need. We have developed ES425, a bispecific ADAPTIR™ (modular protein technology) molecule that redirects T-cell cytotoxicity to tumo