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pro vyhledávání: '"Moller, Annekathrin"'
Autor:
Moller, Annekathrin, Bauer, Claudia S, Cohen, Rebecca N, Webster, Christopher P, De Vos, Kurt J
Publikováno v:
Human Molecular Genetics
Defective axonal transport is an early neuropathological feature of amyotrophic lateral sclerosis (ALS). We have previously shown that ALS-associated mutations in Cu/Zn superoxide dismutase 1 (SOD1) impair axonal transport of mitochondria in motor ne
Autor:
Godena, Vinay K., Brookes-Hocking, Nicholas, Moller, Annekathrin, Shaw, Gary, Oswald, Matthew, Sancho, Rosa M., Miller, Christopher C. J., Whitworth, Alexander J., De Vos, Kurt J.
Publikováno v:
Nature Communications
Godena, V K, Brookes-Hocking, N, Moller, A, Shaw, G, Oswald, M, Sancho, R M, Miller, C C J, Whitworth, A J & De Vos, K J 2014, ' Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations ', Nature Communications, vol. 5, 5245 . https://doi.org/10.1038/ncomms6245
Godena, V K, Brookes-Hocking, N, Moller, A, Shaw, G, Oswald, M, Sancho, R M, Miller, C C J, Whitworth, A J & De Vos, K J 2014, ' Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations ', Nature Communications, vol. 5, 5245 . https://doi.org/10.1038/ncomms6245
Leucine-rich repeat kinase 2 (LRRK2) mutations are the most common genetic cause of Parkinson’s disease. LRRK2 is a multifunctional protein affecting many cellular processes and has been described to bind microtubules. Defective microtubule-based a
Akademický článek
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Autor:
Möller, Annekathrin
Huntington’s Disease (HD) ist eine neurodegenerative Erkrankung, die sich durch motorische, kognitive sowie psychiatrische Beeinträchtigungen auszeichnet. Die Verlängerung eines Polyglutamin (polyQ)-Abschnittes im Protein Huntingtin (Htt) über 3
Externí odkaz:
http://edoc.hu-berlin.de/18452/17227