Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Molindone Hydrochloride"'
Publikováno v:
Environmental and Molecular Mutagenesis. 57:288-298
Molindone hydrochloride is a dihydroindolone neuroleptic with dopamine D2 and D5 receptor antagonist activity. As an integral component of its preclinical safety evaluation, molindone hydrochloride was evaluated in a series of in vitro and in vivo ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c12377295c75ec856bc25e1e81d6edc0
https://doi.org/10.1002/em.22007
https://doi.org/10.1002/em.22007
Neuroleptic drug molindone hydrochloride is a dopamine D2/D5 receptor antagonist and it is in late stage development for the treatment of impulsive aggression in children and adolescents who have attention deficient/hyperactivity disorder (ADHD). Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0f2363a2e983a4bc110ae4079fdfbb
Publikováno v:
Journal of Analytical Toxicology. 28:533-536
Molindone hydrochloride (Moban) is a dihydroindolone compound dissimilar in structure to other antipsychotic drugs (i.e., phenothiazines, butyrophenones, dibenzepines, and thioxanthenes). The antipsychotic (or neuroleptic) activity of molindone makes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8349288b9d12dd209ac397e66a7f83
https://doi.org/10.1093/jat/28.6.533
https://doi.org/10.1093/jat/28.6.533
Publikováno v:
Journal of child and adolescent psychopharmacology. 22(2)
To evaluate safety and tolerability of four doses of immediate-release molindone hydrochloride in children with attention-deficit/hyperactivity disorder (ADHD) and serious conduct problems.This open-label, parallel-group, dose-ranging, multicenter tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d37ea71af19547ff0d7fb0a738f72bf
https://pubmed.ncbi.nlm.nih.gov/22372512
https://pubmed.ncbi.nlm.nih.gov/22372512
Autor:
R. Sandyk
Publikováno v:
The Italian Journal of Neurological Sciences. 11:573-576
The syndrome of "painful legs and moving toes" is characterised by spontaneous causalgic pain in the lower extremities associated with peculiar involuntary movements of the toes and feet. It has been observed after a variety of lesions affecting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09993782016b0a5ccfc10e1904175c37
https://doi.org/10.1007/bf02337440
https://doi.org/10.1007/bf02337440
Autor:
Jeremy D. Gradon
Publikováno v:
DICP : the annals of pharmacotherapy. 25(10)
The case of a patient who developed neuroleptic malignant syndrome (NMS) on three separate occasions is presented. Her third bout of this syndrome possibly was caused by molindone hydrochloride. This medication has been reported only once previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e993b7c1940282d4f453ecc3b0db80
https://pubmed.ncbi.nlm.nih.gov/1803792
https://pubmed.ncbi.nlm.nih.gov/1803792
Publikováno v:
American Journal of Health-System Pharmacy. 38:1750-1753
The visual compatibility of lithium citrate syrup (1.6 meq Li+/ml) in mixtures with each of 10 neuroleptic drug solutions or concentrates was studied. Lithium citrate syrup (5 or 10 ml) was mixed with four volumes (representing minimal to maximal cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4dc29532ed031c7c4341df38cded53a
https://doi.org/10.1093/ajhp/38.11.1750
https://doi.org/10.1093/ajhp/38.11.1750
Akademický článek
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Autor:
Jack M. Rosenberg, Cesar A. Lau-Cam
Publikováno v:
Journal of pharmaceutical sciences. 69(1)
The prolactin response in the rat is proposed as a convenient and inexpensive test system for the assessment of the clinical potency of neuroleptic agents. Times of maximum elevation (p < 0.01) of serum prolactin levels were determined by a one-way a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2864c12c9be870a67ae57bf54f389c5
https://pubmed.ncbi.nlm.nih.gov/6101619
https://pubmed.ncbi.nlm.nih.gov/6101619
Publikováno v:
Journal of pharmaceutical sciences. 62(4)
Preformulation studies on molindone hydrochloride, a dihydroindolone tranquilizer, are described. A TLC assay is outlined, degradation products are identified, and results of stability studies are presented. The dissociation constant is estimated usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce0b1f333587e55f523bff67ef6eaa8
https://pubmed.ncbi.nlm.nih.gov/4698984
https://pubmed.ncbi.nlm.nih.gov/4698984