Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood.

Autor: Borcherding N; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA. Electronic address: borcherding.n@wustl.edu., Jia W; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA., Giwa R; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA., Field RL; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA., Moley JR; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA., Kopecky BJ; Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA., Chan MM; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA., Yang BQ; Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA., Sabio JM; Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO 63110, USA., Walker EC; Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA., Osorio O; Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA., Bredemeyer AL; Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA., Pietka T; Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA., Alexander-Brett J; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA., Morley SC; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA; Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA., Artyomov MN; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA., Abumrad NA; Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA; Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO 63110, USA., Schilling J; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA., Lavine K; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA; Department of Developmental Biology, Washington University School of Medicine, St Louis, MO 63110, USA., Crewe C; Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA; Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO 63110, USA., Brestoff JR; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA. Electronic address: brestoff@wustl.edu.

Publikováno v: Cell metabolism [Cell Metab] 2022 Oct 04; Vol. 34 (10), pp. 1499-1513.e8. Date of Electronic Publication: 2022 Sep 06.

Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity.

Autor: Brestoff JR; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Wilen CB; Department of Laboratory Medicine and Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA., Moley JR; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Li Y; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Zou W; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Malvin NP; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Rowen MN; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Saunders BT; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Ma H; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Mack MR; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110, USA; Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Hykes BL Jr; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Balce DR; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Vir Biotechnology, San Francisco, CA 94158, USA., Orvedahl A; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA., Williams JW; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Rohatgi N; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Wang X; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., McAllaster MR; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Handley SA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Kim BS; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Doench JG; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Zinselmeyer BH; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Diamond MS; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Virgin HW; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Vir Biotechnology, San Francisco, CA 94158, USA; Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Gelman AE; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA., Teitelbaum SL; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: teitelbs@wustl.edu.

Publikováno v: Cell metabolism [Cell Metab] 2021 Feb 02; Vol. 33 (2), pp. 270-282.e8. Date of Electronic Publication: 2020 Dec 04.