Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Molekylärmedicin"'
Autor:
Almqvist, Ylva
Targeted radiotherapy (TRT) of cancer is a promising approach that enables selective treatment of tumour cells, while sparing normal tissue. The humanized monoclonal antibody A33 (huA33) is a potential targeting agent for TRT of colorectal cancer, si
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8657
Autor:
Edholm, Dan
The cardiovascular system is the first functional organ to develop during embryogenesis. As the embryo reaches above a certain size, passive diffusion of gases and nutrients is no longer compatible with efficient growth. During embryogenesis, endothe
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8579
Autor:
Ardesjö, Brita
Inflammatory bowel disease (IBD) comprises diseases that are characterized by chronic or relapsing inflammation of the gastrointestinal tract. Primary sclerosing cholangitis (PSC) is an extraintestinal manifestation in IBD. Immunoreactivity against a
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8677
Autor:
Ericsson, Olle
Padlock probes and proximity ligation are two powerful molecular tools for detection of nucleic acids and proteins, respectively. Both methods result in the formation of DNA reporter molecules upon recognition of specific target molecules. These repo
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8475
Autor:
Rubin, Carl-Johan
Osteoporosis is a disease that leads to decreased bone mineral density (BMD), an altered bone micro-architecture and fragile bones. The disease is highly heritable and numerous genes are thought to be involved, making it difficult to identify the cau
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8498
Autor:
Marits, Per
This thesis deals with recognition and elimination of tumours by T lymphocytes and their use in adoptive immunotherapy. The first tumour-draining lymph node; the sentinel node, is identified by peritumoural injection of a tracer. This is the hypothes
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8325
Autor:
Lendvai, Gábor
Antisense oligonucleotides (ODN) may interfere in gene expression on the basis of hybridising to its complementary messenger RNA (mRNA) sequence in the cell thereby preventing the synthesis of the peptide. Therefore, these ODNs may be potential drugs
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8262
Analysis of Complex Genetic Traits in Population Cohorts using High-throughput Genotyping Technology
Autor:
Dahlgren, Andreas
Most human traits and common diseases have a complex genetic makeup involving more than one gene. The work presented in this thesis investigates standing body height and the common disease type 2 diabetes mellitus (T2DM). In study I we analyzed two s
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8291
Autor:
Schallmeiner, Edith
After the completion of the human genome project the human genome was annotated with the surprisingly small amount of 24 000 (www.ensemble.com) genes. This has focused research on the contribution of splice variants, posttranslational modifications a
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7819
Autor:
Jakobsson, Lars
Blood vessels transport blood with essential nutrients and oxygen to the cells in our body. In a healthy adult, formation of new vessels (angiogenesis) occurs only in case of tissue repair and growth. Physiological angiogenesis requires precise regul
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7666