Zobrazeno 1 - 10
of 3 324
pro vyhledávání: '"Molecular subtype"'
Publikováno v:
Chinese Journal of Lung Cancer, Vol 27, Iss 8, Pp 605-612 (2024)
Small cell lung cancer (SCLC), one of the histological subtypes of lung cancer, is characterized by high proliferation, early metastasis, susceptibility to drug resistance and recurrence. For several years, SCLC has always been regarded as a homogene
Externí odkaz:
https://doaj.org/article/21f9a29f21d646a682b75e6162789b2f
Publikováno v:
Chinese Journal of Lung Cancer, Vol 27, Iss 8, Pp 622-628 (2024)
Large cell neuroendocrine carcinoma (LCNEC) of lung is a rare neuroendocrine carcinoma subtype with difficulty in early diagnosis and poor prognosis which is treated with standard strategies of small cell lung cancer and non-small cell lung cancer. I
Externí odkaz:
https://doaj.org/article/d8504fb9208440fcb89c0495a066f321
Autor:
Jianan Li, Wentao Zhang, Yi Zhao, Jixian Li, Yuanliu Nie, Alei Feng, Qiang Li, Fengge Zhou, Renya Zeng, Zhe Yang
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background With a series of clinical trials confirming the sensitivity of small cell lung cancer (SCLC) to immunotherapy, research on personalized treatment for SCLC has gained increasing attention. Currently, the most widely accepted subtyp
Externí odkaz:
https://doaj.org/article/b0505ec0cd5047b9aaa0129f142b0be4
Autor:
Won-Gun Yun, Daeun Kim, Mirang Lee, Youngmin Han, Yoon Soo Chae, Hye-Sol Jung, Young Jae Cho, Wooil Kwon, Joon Seong Park, Daechan Park, Jin-Young Jang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Pancreatic cancer is anatomically divided into pancreatic head and body/tail cancers, and some studies have reported differences in prognosis. However, whether this discrepancy is induced from the difference of tumor biology is ho
Externí odkaz:
https://doaj.org/article/434a2ece2fe4452d9fc851fc1be36daf
Autor:
Dongze Liu, Zheng Qin, Bocun Yi, Hongbo Xie, Yunan Liang, Liang Zhu, Kuo Yang, Yong Xu, Hongtuan Zhang
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-25 (2024)
Abstract Background Prostate cancer ranks among the six most lethal malignancies worldwide. Telomerase, a reverse transcriptase enzyme, plays a pivotal role in extending cellular telomeres and is intimately associated with cell proliferation and divi
Externí odkaz:
https://doaj.org/article/09b317fcba7746a0846dbddccc277bfa
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-21 (2024)
Abstract Background As the most malignant tumor of the female reproductive system, ovarian cancer (OC) has garnered increasing attention. The Warburg effect, driven by glycolysis, accounts for tumor cell proliferation under aerobic conditions. Howeve
Externí odkaz:
https://doaj.org/article/98e5290f30cb4a13be93fdd137c226d4
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Glioblastoma (GBM) is a highly aggressive, infiltrative malignancy that cannot be completely cured by current treatment modalities, and therefore requires more precise molecular subtype signatures to predict treatment response for personaliz
Externí odkaz:
https://doaj.org/article/eddd09c9c70347e8a7a534b59f7e2412
Autor:
Korina Karagianni, Dimitra Dafou, Konstantinos Xanthopoulos, Theodoros Sklaviadis, Eirini Kanata
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-18 (2024)
Abstract Background Amyotrophic Lateral Sclerosis (ALS) is a highly heterogenous neurodegenerative disorder that primarily affects upper and lower motor neurons, affecting additional cell types and brain regions. Underlying molecular mechanisms are s
Externí odkaz:
https://doaj.org/article/228409947e794c3da43b949786e67eb0
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-16 (2024)
Abstract Background Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) with poor treatment outcomes. The role and underlying mechanisms of ferroptosis in LN remain largely unknown. We aimed to explore ferroptosis-rela
Externí odkaz:
https://doaj.org/article/308a7f1f28884a3c8b96bdb8c8510070
Autor:
Safaa Mohammed Temerik, Saeda Mohamed Abd Elwahab, Mohammed Mostafa Wahman, Mohammed Youssef Ahmed, Mostafa Elsayed Abd Elwanis
Publikováno v:
SVU - International Journal of Medical Sciences, Vol 7, Iss 2, Pp 105-120 (2024)
Background: There are various molecular subtypes of breast cancer. Planning for treatment and predicting the prognosis of breast cancer all depend heavily on breast magnetic resonance imaging (MRI). Objectives: Our study aims to establish the releva
Externí odkaz:
https://doaj.org/article/b8f0d91b55764101a6a59c8b2f11d5ff