Výsledky vyhledávání - "Molecular gastro-enterology and hepatology Translational research [IGMD 2]"

Assessment of plasma aminothiol levels and the association with recurrent atherothrombotic events in patients hospitalized for an acute coronary syndrome: a prospective study

Autor: J. Jaspers Focks, A. Van Schaik, Nick Clappers, Freek W.A. Verheugt, E.J. van Dijk, M. G. H. van Oijen, Wilbert H.M. Peters

Publikováno v: Clinical Chemistry and Laboratory Medicine, 51, 11, pp. 2187-93
Clinical Chemistry and Laboratory Medicine, 51, 2187-93

Background: The aminothiols homocysteine and, to a lesser extent, cysteine have been associated with adverse cardiovascular outcome, whereas glutathione, as an antioxidant, may protect against atherosclerosis and thrombosis. Potentially, the combined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5c00564d8f53b333edb765b6d9cd75
https://hdl.handle.net/2066/125254

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Functional profiles of SCN9A variants in dorsal root ganglion neurons and superior cervical ganglion neurons correlate with autonomic symptoms in small fibre neuropathy

Autor: Sulayman D. Dib-Hajj, Janneke G. J. Hoeijmakers, Shujun Liu, Chongyang Han, Giuseppe Lauria, Ingemar S. J. Merkies, Rene H. M. te Morsche, Catharina G. Faber, Monique M. Gerrits, Stephen G. Waxman, Joost P.H. Drenth

Publikováno v: Brain, 135, 2613-28
Brain, 135, Pt 9, pp. 2613-28
Brain, 135, 2613-2628. Oxford University Press

Item does not contain fulltext Patients with small fibre neuropathy typically manifest pain in distal extremities and severe autonomic dysfunction. However, occasionally patients present with minimal autonomic symptoms. The basis for this phenotypic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5439f0f332e3cded92ccbf0fbec99fc
https://doi.org/10.1093/brain/aws187

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Infliximab exerts no direct hepatotoxic effect on HepG2 cells in vitro

Autor: Henie M. J. Roelofs, Wilbert H.M. Peters, Hilbert S. de Vries, Rene H. M. te Morsche, Dirk J. de Jong, Tineke de Heij

Publikováno v: Digestive Diseases and Sciences, 57, 6, pp. 1604-8
Digestive Diseases and Sciences, 57, 1604-8
Digestive Diseases and Sciences

Contains fulltext : 108348.pdf (Publisher’s version ) (Open Access) BACKGROUND: Infliximab-induced hepatotoxicity is reported in several case studies involving patients with inflammatory bowel disease (IBD) and a direct hepatotoxic effect has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e965b917f6ecd14bbe25beed084bb2a9
https://doi.org/10.1007/s10620-012-2159-7

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High enzyme activity UGT1A1 or low activity UGT1A8 and UGT2B4 genotypes increase esophageal cancer risk

Autor: Wilbert H.M. Peters, Adriaan C.I.T.L. Tan, Hennie M.J. Roelofs, Polat Dura, Theo Wobbes, Ben J.M. Witteman, Rene H. M. te Morsche, Jody Salomon, Joost P.H. Drenth, Jon O. Kristinsson

Publikováno v: International Journal of Oncology, 40, 6, pp. 1789-96
International Journal of Oncology, 40, 1789-96

Contains fulltext : 108111.pdf (Publisher’s version ) (Open Access) Esophageal cancer (EC) has a globally increasing incidence with poor curative treatment options and survival rates. Environmental and dietary factors have crucial roles in esophage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb128e210d945ad369eccb4d8a7313b9
https://hdl.handle.net/2066/108111

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Serum anti-mullerian hormone levels in healthy females: a nomogram ranging from infancy to adulthood

Autor: A.C.S. Hokken-Koelega, Eva Maria Roes, S. Lie Fong, Inger B. Schipper, Corrine K. Welt, A. P. N. Themmen, Marinus J.C. Eijkemans, Jenny A. Visser, Bart C.J.M. Fauser, Y. B. de Rijke, F. H. De Jong, Frank J.M. Broekmans, Wilbert H.M. Peters, Joop S.E. Laven

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 97, 4650-5
Journal of Clinical Endocrinology and Metabolism, 97, 12, pp. 4650-5
Journal of Clinical Endocrinology and Metabolism, 97(12), 4650-4655. Endocrine Society

Item does not contain fulltext Context: Anti-Mullerian hormone (AMH) is an accurate marker of ovarian reserve. However, sufficiently large sets of normative data from infancy to the end of reproductive life are scarce. Objective: This study was an as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5001759b43470104d2e3ad4271337e79
https://doi.org/10.1210/jc.2012-1440

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Untreated celiac disease in a patient with dermatitis herpetiformis leading to a small bowel carcinoma

Autor: Derikx, M.H.M., Bisseling, T.M.

Publikováno v: Case Reports in Gastroenterology, 6, 1, pp. 20-5
Case Reports in Gastroenterology, 6, 20-5

Contains fulltext : 110107.pdf (Publisher’s version ) (Open Access) Usually, celiac disease has a benign course, though the overall morbidity and mortality have increased. Treatment with a gluten-free diet restores the damaged intestinal mucosa. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6db85b323f22e1c73f14eb1515426eef
https://hdl.handle.net/2066/110107

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Short-term infusion of a fish oil-based lipid emulsion modulates fatty acid status, but not immune function or (anti)oxidant balance: a randomized cross-over study

Autor: Versleijen, M.W.J., Schaap-Roelofs, H.M.J., Rombouts, C., Hermans, P.W.M., Noakes, P.S., Calder, P.C., Wanten, G.J.A.

Publikováno v: European Journal of Clinical Investigation, 42, 3, pp. 290-302
European Journal of Clinical Investigation, 42, 290-302

Contains fulltext : 109527.pdf (Publisher’s version ) (Closed access) BACKGROUND AND AIMS: Studies suggest clinical benefits of parenteral fish oil (FO), rich in n-3 polyunsaturated fatty acids (PUFAs), over soyabean oil (SO), rich in n-6 PUFAs, in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7d58162fae04b157e14fda5a8fe68557
https://doi.org/10.1111/j.1365-2362.2011.02582.x

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Deletion mutation of sodium channel NaV1.7 in inherited erythromelalgia: enhanced slow inactivation modulates dorsal root ganglion neuron hyperexcitability

Autor: Xiaoyang Cheng, Sulayman D. Dib-Hajj, Stephen G. Waxman, Lynda Tyrrell, Rene H. M. te Morsche, Joost P.H. Drenth

Publikováno v: Brain, 134, Pt 7, pp. 1972-86
Brain, 134, 1972-86

Item does not contain fulltext Gain-of-function missense mutations of voltage-gated sodium channel Na(V)1.7 have been linked to the painful disorder inherited erythromelalgia. These mutations hyperpolarize activation, slow deactivation and enhance cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5ee0f535edcb522ae7ce7e8926286e
https://doi.org/10.1093/brain/awr143

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[Visceral leishmaniasis: not only a tropical disease]

Autor: Cuperus, F.J.C., Oosterwijk, P.R., Vos, A., Remijn, J.A., Dobbenburgh, A. van, Bisseling, T.M.

Publikováno v: Nederlands Tijdschrift voor Geneeskunde, 157, 27, pp. A5958
Nederlands Tijdschrift voor Geneeskunde, 157, A5958

Item does not contain fulltext We report 2 cases of visceral leishmaniasis in Dutch patients after a stay in Greece and the former Yugoslavia, respectively. Patient A, a 69-year-old woman, was referred to our department with abdominal pain. Additiona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::837b7a866687389e9625d3385f99cc75
https://hdl.handle.net/2066/119067

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