Familial gastric cancer: guidelines for diagnosis, treatment and periodic surveillance

Autor: Irma, Kluijt, Rolf H, Sijmons, Nicoline, Hoogerbrugge, John T, Plukker, Daphne, de Jong, J Han, van Krieken, Richard, van Hillegersberg, Marjolijn, Ligtenberg, Eveline, Bleiker, Anemieke, Cats, E, Bleiker

Publikováno v: Familial Cancer, 11, 363-9
Familial Cancer, 11, 3, pp. 363-9
Familial cancer, 11(3), 363-369. Springer Netherlands
Familial Cancer, 11(3), 363-369. SPRINGER

Contains fulltext : 107891.pdf (Publisher’s version ) (Closed access) Hereditary diffuse gastric cancer (HDGC) is a relatively rare disorder, with a mutated CDH1 gene as the only known cause. Carriers of a germline mutation in CDH1 have a lifetime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83878b8765096f0fa579342a48f1341
https://doi.org/10.1007/s10689-012-9521-y

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

Autor: Ramnik J. Xavier, Jessica Quintin, Daniela C. Ifrim, Dirk J. de Jong, Joke van Loenhout, Leo A. B. Joosten, Sadia Saeed, Jos W. M. van der Meer, Reinout van Crevel, Cor Jacobs, Johanneke Kleinnijenhuis, Hendrik G. Stunnenberg, Frank Preijers, Mihai G. Netea

Publikováno v: Proceedings of the National Academy of Sciences USA, 109, 17537-17542
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (43), pp.17537-17542. ⟨10.1073/pnas.1202870109⟩
Proceedings of the National Academy of Sciences USA, 109, 43, pp. 17537-17542

Item does not contain fulltext Adaptive features of innate immunity, recently described as "trained immunity," have been documented in plants, invertebrate animals, and mice, but not yet in humans. Here we show that bacille Calmette-Guerin (BCG) vacc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b80c192041b7b9a8c7f326df177634d
https://hdl.handle.net/2066/103888

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

Autor: Mélissa Beaudoin, Stephan Ripke, Jonas Halfvarson, Leif Törkvist, Dermot P.B. McGovern, Caroline Lagacé, Todd Green, David Ellinghaus, Mauro D'Amato, Andrew Kirby, Manuel A. Rivas, Steven R. Brant, Ramnik J. Xavier, Stacey Gabriel, Guillaume Lettre, Joshua M. Korn, Philippe Goyette, Finny G Kuruvilla, Clarence K. Zhang, Noël P. Burtt, Agnes Gardet, Richard H. Duerr, Timothy Fennell, Yashoda Sharma, Benjamin M. Neale, Andre Franke, Ken Sin Lo, David Altshuler, Gabrielle Boucher, Talin Haritunians, Marla Dubinsky, Phil Schumm, John D. Rioux, Mark J. Daly, Judy H. Cho, Mark S. Silverberg, Anna Latiano, Christine Stevens

Publikováno v: Nature Genetics, 43(11), 1066-U50
Nature Genetics, 43, 1066-73
Nature Genetics, 43, 11, pp. 1066-73
Nature genetics, 43(11), 1066-1073. Nature Publishing Group
Nature genetics

Item does not contain fulltext More than 1,000 susceptibility loci have been identified through genome-wide association studies (GWAS) of common variants; however, the specific genes and full allelic spectrum of causal variants underlying these findi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5631976096d34f7e08a3c37059592c
https://doi.org/10.1038/ng.952

Update on the management of ulcerative colitis

Autor: Frank Hoentjen, Atsushi Sakuraba, Stephen B. Hanauer

Publikováno v: Current Gastroenterology Reports, 13, 475-85
Current Gastroenterology Reports, 13, pp. 475-85

The treatment options for inflammatory bowel disease have expanded with the introduction of biological therapies. Recently published controlled clinical trials were searched and those that impact the clinical management of ulcerative colitis (UC) are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::520a54257491cec7417f0483b5706877
https://hdl.handle.net/2066/98501

Adenomas in Patients with Inflammatory Bowel Disease Are Associated with an Increased Risk of Advanced Neoplasia

Autor: Schaik, F.D.M. van, Mooiweer, E., Have, M. van der, Belderbos, T.D.G., Kate, F.J.W. ten, Offerhaus, G.J.A., Schipper, M.E.I., Dijkstra, G., Pierik, M., Stokkers, P.C.F., Ponsioen, C., Jong, D.J. de, Hommes, D.W., Bodegraven, A.A. van, Siersema, P.D., Oijen, M.G.H. van, Oldenburg, B., Dutch Initiative Crohn Colitis ICC

Publikováno v: Inflammatory Bowel Diseases, 19(2), 342-349. LIPPINCOTT WILLIAMS & WILKINS
Inflammatory Bowel Diseases, 19(2), 342-349
Inflammatory Bowel Diseases, 19(2), 342-349. John Wiley and Sons Inc.
Inflammatory bowel diseases, 19(2), 342-349. John Wiley and Sons Inc.
van Schaik, F D M, Mooiweer, E, ten Have, M, Belderbos, T D G, Ten Kate, F J W, Offerhaus, G J A, Schipper, M E I, Dijkstra, G, Pierik, M, Stokkers, P C F, Ponsioen, C, de Jong, D J, Hommes, D W, van Bodegraven, A A, Siersema, P D, van Oijen, M G H & Oldenburg, B 2013, ' Adenomas in Patients with Inflammatory Bowel Disease Are Associated with an Increased Risk of Advanced Neoplasia ', Inflammatory Bowel Diseases, vol. 19, no. 2, pp. 342-349 . https://doi.org/10.1097/MIB.0b013e318286f771
Inflammatory Bowel Diseases, 19, 342-349
Inflammatory Bowel Diseases, 19, 2, pp. 342-349
Inflammatory Bowel Diseases, 19(2), 342-349. Oxford University Press

Background: It is still unclear whether inflammatory bowel disease (IBD) patients with adenomas have a higher risk of developing high-grade dysplasia (HGD) or colorectal cancer (CRC) than non-IBD patients with sporadic adenomas. We compared the risk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db530a3678dc6ebd2de176ddce8ba6fa
https://cris.maastrichtuniversity.nl/en/publications/db3bb6e9-26c6-450d-b802-2575b423c2e5