Zobrazeno 1 - 10
of 6 549
pro vyhledávání: '"Molecular dynamic simulation"'
Autor:
Fariba Keshavarzipour, Maryam Abbasi, Zahra Khorsandi, Mina Ardestani, Hojjat Sadeghi-Aliabadi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Heat shock protein 90 (Hsp90), a molecular chaperone, contributes to the preservation of folding, structure, stability, and function proteins. In this study, novel compounds comprising isoxazole structure were designed, synthesized and their
Externí odkaz:
https://doaj.org/article/5f84026d397f4c8b9ffded5e79441681
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract This work investigates the efficiency of green-synthesized WO3 nanoflakes for the removal of methylene blue dye. The synthesis of WO3 nanoflakes using Hyphaene thebaica fruit extract results in a material with a specific surface area of 13 m
Externí odkaz:
https://doaj.org/article/323a542f313b41a9a4af1cb28e19431f
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 10, Pp 11503-11518 (2024)
Diabetes mellitus (DM) is a complex metabolic disorder characterized by chronic hyperglycemia, with aldose reductase playing a critical role in the pathophysiology of diabetic complications. This study aimed to investigate the efficacy of flavonoid c
Externí odkaz:
https://doaj.org/article/7faff422c0e5490fbd36c27925a51a3d
Autor:
Giusy Tassone, Samuele Maramai, Marco Paolino, Stefania Lamponi, Federica Poggialini, Elena Dreassi, Elena Petricci, Stefano Alcaro, Cecilia Pozzi, Isabella Romeo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Bioconjugation is one of the most promising strategies to improve drug delivery, especially in cancer therapy. Biomolecules such as bile acids (BAs) have been intensively explored as carriers, due to their peculiar physicochemical properties
Externí odkaz:
https://doaj.org/article/1a4c84aa763544cdb95cf8741a3df437
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Limonoids are important constituents of citrus that have a significant impact on promoting human health. Therefore, the primary focus of this research was to assess the overall limonoid content and isolate limonoids from Adalia lemon (Citrus
Externí odkaz:
https://doaj.org/article/983676aae439459c944186f88d91e025
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Borophene, a novel two-dimensional material unveiled in 1998, has garnered significant interest among researchers due to its distinct mechanical and electrical characteristics. Efforts to experimentally synthesize borophene continue to capti
Externí odkaz:
https://doaj.org/article/d95379acd0a442428c4ca72f3f8fe031
Autor:
Ali Afgar, Mahdiyeh Ramezani Zadeh Kermani, Athareh Pabarja, Amir Reza Afgar, Batoul Kavyani, Hossein Arezoomand, Saeed Zanganeh, Mohammad Javad Sanaei, Mahla Sattarzadeh Bardsiri, Reza Vahidi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract This investigation delves into the influence of predicted microRNAs on DNA methyltransferases (DNMTs) and the PODXL gene within the NB4 cell line, aiming to elucidate their roles in the pathogenesis of acute myeloid leukemia (AML). A compreh
Externí odkaz:
https://doaj.org/article/326231482dfd474a82b02c425fd897f1
Publikováno v:
Shipin Kexue, Vol 45, Iss 14, Pp 14-22 (2024)
This study aims to investigate the influence of the carboxyl substituent groups and the carbon chain length of acrylic acid of ferulic acid (FA) on its bitterness inhibitory effect. Molecular dynamics simulations were employed to analyze the conforma
Externí odkaz:
https://doaj.org/article/29f9d83d6ebc4b0681a0eb78ac81a6cb
Autor:
Daniel Uwaremhevho Momodu, Toluwase Hezekiah Fatoki, Oluwaseyi Samuel Alebiosu, Deborah Ebunoluwa Ojo, Olapade Samuel Akinlolu, Adedayo Olamide Oyebanji
Publikováno v:
Jurnal Kesehatan Lingkungan, Vol 16, Iss 3, Pp 200-212 (2024)
Introduction: The study investigated the molecular effects of human exposure to commonly used pesticides in Nigeria. Methods: Utilizing computational methods like clustering analysis, toxicokinetic predictions, molecular docking, and molecular dynami
Externí odkaz:
https://doaj.org/article/9bbc3d73099b4a459b9e87175d88e72f
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Porcine Rotavirus (PoRV) is a significant pathogen affecting swine-rearing regions globally, presenting a substantial threat to the economic development of the livestock sector. At present, no specific pharmaceuticals are available for this
Externí odkaz:
https://doaj.org/article/45086ebacb814ab889120e1ff70e8384