Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Molecular biophysics (biochemistry)"'
Autor:
Rouse, S
The influenza BM2 proton channel is a small, tetrameric α-helical membrane protein, which is vital in multiple stages of the life cycle of the virus. The transmembrane (TM) domain is responsible for modulating pH to facilitate release of viral genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::249838df78b9037e84579c8c0d90eb10
https://ora.ox.ac.uk/objects/uuid:54427591-7c70-46dc-8f75-d7c991fbfc02
https://ora.ox.ac.uk/objects/uuid:54427591-7c70-46dc-8f75-d7c991fbfc02
Autor:
Malinauskas, T
Wnt morphogens control embryonic development and adult tissue homeostasis. Deregulation of the Wnt signalling pathway leads to human diseases. This thesis covers work on two antagonists of the Wnt signalling pathway, Wnt inhibitory factor 1 (WIF-1) (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::897a0d162126a17855393645ab5871ee
https://ora.ox.ac.uk/objects/uuid:a3b71f18-9b90-408a-a5b5-2611e4ae2102
https://ora.ox.ac.uk/objects/uuid:a3b71f18-9b90-408a-a5b5-2611e4ae2102
Autor:
Gheysens, T
Whereas most silk research is focused on silk proteins, the focus of this thesis is on small molecules present in silk and why they are so important for anyone working in this field with silk. Silks are known to perform a range of different functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::6e74de86c8d27c66dcc472f5ce1b492c
https://ora.ox.ac.uk/objects/uuid:a5eb2de3-f921-4839-a764-bf369e6b0d88
https://ora.ox.ac.uk/objects/uuid:a5eb2de3-f921-4839-a764-bf369e6b0d88
Autor:
Ng, HK
Sequestration of infected erythrocytes during P. falciparum infection can lead to severe malaria. PfEMP1 proteins are central to this process. Multimodular PfEMP1 proteins can bind to a variety of human ligands due to the presence of CIDR and DBL dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::6ce4fb75dcdaad6efd6740ddd686ec29
https://ora.ox.ac.uk/objects/uuid:44d5d63e-823e-4ecc-8d6c-0c9a5ae23e89
https://ora.ox.ac.uk/objects/uuid:44d5d63e-823e-4ecc-8d6c-0c9a5ae23e89
Autor:
Adamson, R
The G protein-coupled receptor (GPCR), neurotensin receptor type 1 (NTS1), is pharmacologically important and activated by the tridecapeptide hormone, neurotensin (NT), initiating a cascade of interactions through G proteins to effect cellular respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::b1709399de0b75ece93d7826261386c2
https://ora.ox.ac.uk/objects/uuid:d24b4be6-65d6-4b3c-b049-5c6d1e737f1e
https://ora.ox.ac.uk/objects/uuid:d24b4be6-65d6-4b3c-b049-5c6d1e737f1e
Autor:
Adam Raes, Alain J. Labro, Alessandro Grottesi, Mark S.P. Sansom, Diane Van Hoorick, Dirk J. Snyders
Publikováno v:
Scopus-Elsevier
The journal of general physiology
JOURNAL OF GENERAL PHYSIOLOGY
The Journal of General Physiology
The journal of general physiology
JOURNAL OF GENERAL PHYSIOLOGY
The Journal of General Physiology
Voltage-dependent K(+) channels transfer the voltage sensor movement into gate opening or closure through an electromechanical coupling. To test functionally whether an interaction between the S4-S5 linker (L45) and the cytoplasmic end of S6 (S6(T))
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e392bb9972118ec2336205a3bb4f14
https://doi.org/10.1085/jgp.200810048
https://doi.org/10.1085/jgp.200810048
Autor:
Brady, J
Integral membrane proteins of the DP1 and reticulon families are responsible for maintaining the high membrane curvature required for both smooth ER tubules and the edges of ER sheets. Mutations in these proteins lead to motor neurone diseases such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::77ae954e78e4413f9f34c1f924654285
https://ora.ox.ac.uk/objects/uuid:fb5ce78d-0bc8-46dd-9552-04f1f1ec1d0f
https://ora.ox.ac.uk/objects/uuid:fb5ce78d-0bc8-46dd-9552-04f1f1ec1d0f
Autor:
Williamson, A, Williamson, A J
The self-assembly of structured particles into monodisperse clusters is a challenge on the nano-, micro- and even macro-scale. While biological systems are able to self-assemble with comparative ease, many aspects of this self-assembly are not fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::7718e6d9e19a24d797b2e6d6964fa80f
https://ora.ox.ac.uk/objects/uuid:9eb549f9-3372-4a38-9370-a9b0e58ca26b
https://ora.ox.ac.uk/objects/uuid:9eb549f9-3372-4a38-9370-a9b0e58ca26b
Autor:
Lumb, CN
In order to associate with the cytoplasmic leaflet of the plasma membrane, many cytosolic signalling proteins possess a distinct lipid binding domain as part of their overall fold. Here, a multiscale simulation approach has been used to investigate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::c564a31fd7ff88b81a725c2a738b3fd0
https://ora.ox.ac.uk/objects/uuid:d5b2db00-1050-4191-8eff-3521a4885a0c
https://ora.ox.ac.uk/objects/uuid:d5b2db00-1050-4191-8eff-3521a4885a0c
Protein tertiary structure is more conserved than amino acid sequence, leading to a diverse range of functions observed in the same fold. Despite < 20 % overall sequence identity, cytochromes P450 all have the same fold. Bacterial Class I P450s recei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::c7b7c2312413cc0253b175c87fde7be3
https://ora.ox.ac.uk/objects/uuid:d19f5f52-d1ce-4ec2-be83-fd52f01124f8
https://ora.ox.ac.uk/objects/uuid:d19f5f52-d1ce-4ec2-be83-fd52f01124f8