Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Molecular Chaperones/genetics/metabolism"'
Autor:
Carole Sourbier, Robert P. Mohney, Manabu Tatokoro, Fumitaka Koga, Hisashi Hasumi, Ken Nakamura, Kristin Beebe, Naoto Miyajima, Leonard M. Neckers, Wanping Xu, Didier Picard, Soichiro Yoshida, Hiroshi Fukushima, Jane B. Trepel, Min-Jung Lee, Guillaume Muhlebach, Sunmin Lee, Evangelia Vartholomaiou, Yang Chen, Kazunori Kihara, Shinji Tsutsumi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 110, iss 17
Proceedings of the National Academy of Sciences, Vol. 110, No 17 (2013) pp. E1604-12
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences, Vol. 110, No 17 (2013) pp. E1604-12
Proceedings of the National Academy of Sciences of the United States of America
TRAP1 (TNF receptor-associated protein), a member of the HSP90 chaperone family, is found predominantly in mitochondria. TRAP1 is broadly considered to be an anticancer molecular target. However, current inhibitors cannot distinguish between HSP90 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c273fd67390d149a0496310b4c9dae8c
https://doi.org/10.1073/pnas.1220659110
https://doi.org/10.1073/pnas.1220659110
Publikováno v:
Molecular and Cellular Biology, Vol. 29, No 8 (2009) pp. 2322-2334
Pax6 is important in the development of the pancreas and was previously shown to regulate pancreatic endocrine differentiation, as well as the insulin, glucagon, and somatostatin genes. Prohormone convertase 2 (PC2) is the main processing enzyme in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c5236d1e1c8118fb84053c76a0e1dc
https://europepmc.org/articles/PMC2663301/
https://europepmc.org/articles/PMC2663301/
Autor:
Shozo Izui, Lucie Clementine Baudino, Bernard J Morley, Naoki Morito, Isabelle Dunand-Sauthier, Kumiko Yoshinobu, Marie-Laure Santiago-Raber, Leonard H. Evans
Publikováno v:
Journal of Immunology, Vol. 182, No 12 (2009) pp. 8094-103
Endogenous retroviruses are implicated in the pathogenesis of systemic lupus erythematosus (SLE). Because four different classes of endogenous retroviruses, i.e., ecotropic, xenotropic, polytropic, or modified polytropic (mPT), are expressed in mice,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f01e65bb00ee3c5c74367ae8968c5d2
https://archive-ouverte.unige.ch/unige:5579
https://archive-ouverte.unige.ch/unige:5579
Autor:
Thomas Ratajczak, Samantha C. Chirillo, Daniel L. Riggs, David F. Smith, Richard F. Gaber, Didier Picard, Patricia J. Roberts, Viravan Prapapanich, Joyce Cheung-Flynn
Publikováno v:
EMBO Journal, Vol. 22, No 5 (2003) pp. 1158-67
Hsp90 is required for the normal activity of steroid receptors, and in steroid receptor complexes it is typically bound to one of the immunophilin-related co-chaperones: the peptidylprolyl isomerases FKBP51, FKBP52 or CyP40, or the protein phosphatas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d63b40f154a3cbee2d7dd349a55733
https://archive-ouverte.unige.ch/unige:4615
https://archive-ouverte.unige.ch/unige:4615
Publikováno v:
Molecular and Cellular Biology, Vol. 21, No 22 (2001) pp. 7569-75
The highly abundant molecular chaperone Hsp90 functions with assistance from auxiliary factors, collectively referred to as Hsp90 cochaperones, and the Hsp70 system. Hsp104, a molecular chaperone required for stress tolerance and for maintenance of [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc23ddfa309ec1dbe72fb08ebdf8ee08
https://pubmed.ncbi.nlm.nih.gov/11604493
https://pubmed.ncbi.nlm.nih.gov/11604493
Autor:
Humbert De Smedt, Anna Zuppini, Serge Arnaudeau, Nicolas Demaurex, Ryoko Krause, Jan B. Parys, Jeffery Lynch, Daniel Pablo Lew, Marek Michalak, Michal Opas, Karl-Heinz Krause, Kimitoshi Nakamura, Sylvia Papp, Werner Müller-Esterl, Irfan Ahsan
Publikováno v:
The Journal of Cell Biology
The Journal of Cell Biology, Vol. 154, No 5 (2001) pp. 961-972
The Journal of Cell Biology, Vol. 154, No 5 (2001) pp. 961-972
Calreticulin is a Ca2+-binding chaperone in the endoplasmic reticulum (ER), and calreticulin gene knockout is embryonic lethal. Here, we used calreticulin-deficient mouse embryonic fibroblasts to examine the function of calreticulin as a regulator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c94841c6dce62c9706014d2e6bcf2b
https://pubmed.ncbi.nlm.nih.gov/11524434
https://pubmed.ncbi.nlm.nih.gov/11524434