Zobrazeno 1 - 10
of 606
pro vyhledávání: '"Molecular Biophysics Unit"'
Autor:
Pooja Jorwal, Sujit Kumar Sikdar
Publikováno v:
Epilepsia. 60:2370-2385
Objective Much evidence suggests that the subiculum plays a significant role in the regulation of epileptic activity. Lactate acts as a neuroprotective agent against many conditions that cause brain damage. During epileptic seizures, lactate formatio
Publikováno v:
FEBS Open Bio, Vol 9, Iss 11, Pp 1848-1859 (2019)
FEBS Open Bio
FEBS Open Bio
Homologous domains embedded in multidomain proteins of different domain architectures (DA) may exhibit subtle, but important, differences in their structure and function. Here, we consider two multidomain proteins, Arf nucleotide binding site opener
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
PubMed Central
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DOAJ-Articles
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Microsoft Academic Graph
Open Access Repository of IISc Research Publications
Scientific Reports
PubMed Central
Datacite
DOAJ-Articles
UnpayWall
ORCID
Microsoft Academic Graph
Open Access Repository of IISc Research Publications
Scientific Reports
Toxin-antitoxin (TA) systems are ubiquitously existing addiction modules with essential roles in bacterial persistence and virulence. The genome of Mycobacterium tuberculosis encodes approximately 79 TA systems. Through computational and experimental
Autor:
Poonam Mishra, Rishikesh Narayanan
Publikováno v:
Hippocampus
The ability of a neuronal population to effectuate channel decorrelation, which is one form of response decorrelation, has been identified as an essential prelude to efficient neural encoding. To what extent are diverse forms of local and afferent he
Autor:
Sukrut C. Kamerkar, Anand Srivastava, Thomas J. Pucadyil, Raunaq Deo, Nagesh Y. Kadam, Manish S. Kushwah, Kavita Babu, Srishti Dar
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications
Nature Communications
Endocytic and recycling pathways generate cargo-laden transport carriers by membrane fission. Classical dynamins, which generate transport carriers during endocytosis, constrict and cause fission of membrane tubes in response to GTP hydrolysis. Relat
Autor:
Rishikesh Narayanan, Abha Jain
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Hippocampal pyramidal neurons are endowed with signature excitability characteristics, exhibit theta-frequency selectivity — manifesting as impedance resonance and as a band-pass structure in the spike-triggered average (STA) — and coincidence de
Publikováno v:
Archives of Virology. 164:497-507
The capsids of viruses have a high degree of symmetry. Therefore, virus nanoparticles (VNPs) can be programmed to display many imaging agents precisely. Plant VNPs are biocompatible, biodegradable and non-infectious to mammals. We have carried out bi
Autor:
Rishikesh Narayanan, Sufyan Ashhad
Publikováno v:
Molecular neurobiology
Glial cells and neuronal dendrites were historically assumed to be passive structures that play only supportive physiological roles, with no active contribution to information processing in the central nervous system. Research spanning the past few d
Publikováno v:
Archives of Virology. 163:1531-1547
Rotavirus nonstructural protein 4, the first viral enterotoxin to be identified, is a multidomain, multifunctional glycoprotein. Earlier, we reported a Ca2+-bound coiled-coil tetrameric structure of the diarrhea-inducing region of NSP4 from the rotav
Autor:
Mahesh P. Gupta, Sneha Mishra, Mohsen Sarikhani, Mahavir Singh, Chaithanya Kotyada, Nagalingam R. Sundaresan, Perumal Arumugam Desingu, Donald Wolfgeher
Publikováno v:
Cell Death & Differentiation. 25:1638-1656
c-Jun NH(2)-terminal kinases (JNKs) are responsive to stress stimuli and their activation regulate key cellular functions, including cell survival, growth, differentiation and aging. Previous studies demonstrate that activation of JNK requires dual p