Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Molecular Biology Display Techniques"'
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0151184 (2016)
PLoS ONE, Vol 11, Iss 3, p e0151184 (2016)
Aims To isolate and characterise phage which could lyse P. acnes and to formulate the phage into a delivery form for potential application in topical treatment of acne infection. Methods and Results Using standard phage isolation techniques, ten phag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d75eed7073471bc6069b36b98ee5822
Autor:
Ki Eun Maeng, Lauren Greenberg, Madhusudana N. Shampur, Jun-Young Lee, Richard Franka, Cheol Min Kim, Modupe O. V. Osinubi, Sun Ju Keum, Soo Young Lee, Ji Min Seo, Hyunjoo Lee, Jung Sun Ahn, Kye Sook Yi, Minsoo Kim, Ji-Young Shin, Pan Kyeom Kim, Min Joo Choo, Charles E. Rupprecht
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0256779 (2021)
PLoS ONE, Vol 16, Iss 9, p e0256779 (2021)
Post-exposure prophylaxis (PEP) is highly effective in preventing disease progression of rabies when used in timely and appropriate manner. The key treatment for PEP is infiltration of rabies immune globulin (RIG) into lesion site after bite exposure
Autor:
Chanvit Leelayuwat, Aijaz Ahmad Malik, Sitthinon Siripanthong, Anchalee Techasen, Amonrat Jumnainsong, Paiboon Sithithaworn, Chanin Nantasenamat
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0248887 (2021)
PLoS ONE, Vol 16, Iss 3, p e0248887 (2021)
In this study, a key issue to be addressed is the safe disposal of hybridoma instability. Hybridoma technology was used to produce anti–O. viverrini monoclonal antibody. Previous studies have shown that antibody production via antibody phage displa
Autor:
John D. Gross, Natalia Sevillano, Dong Young Kim, André Luiz Lourenço, James H. Hurley, Xi Liu, Xuefeng Ren, Evan M. Green, Jörg Votteler, Bei Yang, Shauna Farr-Jones, Charles S. Craik, Yifan Cheng
Publikováno v:
PloS one, vol 16, iss 5
PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0250318 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0250318 (2021)
Viral infection and pathogenesis is mediated by host protein—viral protein complexes that are important targets for therapeutic intervention as they are potentially less prone to development of drug resistance. We have identified human, recombinant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49550d230f28a0858a40cd84c7e8cae
https://escholarship.org/uc/item/05j700fv
https://escholarship.org/uc/item/05j700fv
Autor:
Kazuhiko Yamasaki, Takashi Yaegashi, Michiko N. Fukuda, Hideaki Mabashi-Asazuma, Itsuko Kimura-Takagi, Motohiro Nonaka, Masato Nagaoka, Toshio Sasai, Chizuko Nishizawa-Harada, Chun-Teng Huang, Yoichi Suwa, Tomoya O. Akama, Donald L. Jarvis
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0241157 (2021)
PLoS ONE
PLoS ONE
IF7 peptide, which binds to the annexin A1 (ANXA1) N-terminal domain, functions as a tumor vasculature-targeted drug delivery vehicle after intravenous injection. To enhance IF7 stability in vivo, we undertook mirror-image peptide phage display using
Autor:
Jukka Kervinen, Srinivas Akula, Jinhye Ryu, Michael Thorpe, Lars Hellman, Zhirong Fu, Chang Qiao, Gurdeep Chahal, Lawrence de Garavilla
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0252624 (2021)
PLoS ONE, Vol 16, Iss 5, p e0252624 (2021)
Ruminants have a very complex digestive system adapted for the digestion of cellulose rich food. Gene duplications have been central in the process of adapting their digestive system for this complex food source. One of the new loci involved in food
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008101 (2021)
PLoS Computational Biology
PLoS Computational Biology
Proteases are an important class of enzymes, whose activity is central to many physiologic and pathologic processes. Detailed knowledge of protease specificity is key to understanding their function. Although many methods have been developed to profi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169221cf601b5e57806ed8c09b6a052f
https://doi.org/10.1101/2020.06.30.179820
https://doi.org/10.1101/2020.06.30.179820
Autor:
Tiffany Pointon, Michael W. Graner, Sean Manton, Miyoko Green, Mollie Davis, Timothy Vollmer, Anthony Fringuello, Kathryn Dennison, Gino Braiotta, Taylor Edwards, Julia Craft, Xiaoli Yu, Bailey Polonsky
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 2, p e0228883 (2020)
PLoS ONE, Vol 15, Iss 2, p e0228883 (2020)
IgG oligoclonal bands (OCBs) are present in the cerebrospinal fluid (CSF) of more than 95% of patients with multiple sclerosis (MS), and are considered to be the immunological hallmark of disease. However, the target specificities of the IgG in MS OC
Autor:
Jing Wang, Shaghayegh Morshedian, Joey P. Ting, Alfonso Espada, Carina Torres, Kai Zhang, Sayers Robert Owen, Priyanka Pandya, Howard B. Broughton, J.R. Fitchett, Juan J. Carrillo, Jim D. Durbin, Qing Zhang, Justine S. Cudal, Yuewei Qian, Feiyu F. Zhang, Sepideh Afshar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0233961 (2020)
PLoS ONE, Vol 15, Iss 6, p e0233961 (2020)
Hundreds of target specific peptides are routinely discovered by peptide display platforms. However, due to the high cost of peptide synthesis only a limited number of peptides are chemically made for further analysis. Here we describe an accurate an
Autor:
Ljudmila A. Emelyanova, Julia S. Savinova, Irina V. Kozlova, Andrey L. Matveev, Elena K. Doroshchenko, Nina V. Tikunova, Oleg V. Stronin, Oksana V. Lisak, Yana A. Khlusevich, Olga V. Suntsova, Ivan K. Baykov, V. A. Matveeva
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 4, p e0215075 (2019)
PLoS ONE, Vol 14, Iss 4, p e0215075 (2019)
Tick-borne encephalitis virus (TBEV) is the most important tick-transmitted pathogen. It belongs to the Flaviviridae family and causes severe human neuroinfections. In this study, protective efficacy of the chimeric antibody chFVN145 was examined in