Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Molecular Biology/RNA-Protein Interactions"'
Autor:
Bertrand Tavitian
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228838 (2020)
PLoS ONE
PLoS ONE
The hope of success of therapeutic interventions largely relies on the possibility to distinguish between even close tumor types with high accuracy. Indeed, in the last ten years a major challenge to predict the responsiveness to a given therapeutic
Autor:
Richard Robinson
Publikováno v:
PLoS Biology
PLoS Biology, Vol 9, Iss 4, p e1001047 (2011)
PLoS Biology, Vol 9, Iss 4, p e1001047 (2011)
The localization of ash mRNA in yeast requires the binding of She2p and the myosin adaptor protein She3p to its localization element, which is highly specific and leads to the assembly of stable transport complexes.
In eukaryotes, hundreds of mR
In eukaryotes, hundreds of mR
Autor:
Birgit Seidelt, Shashi Bhushan, Jens Frauenfeld, Thomas Hoffmann, Thorsten Mielke, Otto Berninghausen, Roland Beckmann, Daniel N. Wilson
Publikováno v:
PLoS Biology, Vol 9, Iss 1, p e1000581 (2011)
PLoS Biology
PLoS Biology
A structure of a ribosome stalled during translation of the SecM peptide provides insight into the mechanism by which the large subunit active site is inactivated.
As nascent polypeptide chains are synthesized, they pass through a tunnel in the
As nascent polypeptide chains are synthesized, they pass through a tunnel in the
Autor:
Te Velthuis, AJW, van den Worm, SH, Sims, AC, Baric, RS, Snijder, EJ, van Hemert, MJ, Andino, R
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001176 (2010)
PLoS Pathogens
PLoS Pathogens, 6(11)
PLoS Pathogens
PLoS Pathogens, 6(11)
Increasing the intracellular Zn2+ concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses, including poliovirus and influenza virus. For some viruses this effect has been attributed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d026c5e2853f7a9664ff8d66af9a222
https://hdl.handle.net/1887/110338
https://hdl.handle.net/1887/110338
Autor:
Tara Vanderwyde, Michael Y. Sherman, Yong Jie Zhang, Robert Bowser, Nava Zaarur, Tapan Mehta, Allison Citro, Liqun Liu-Yesucevitz, Ann C. McKee, Benjamin Wolozin, Leonard Petrucelli, Aylin Bilgutay
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13250 (2010)
PLoS ONE
PLoS ONE
Tar DNA Binding Protein-43 (TDP-43) is a principle component of inclusions in many cases of frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). TDP-43 resides predominantly in the nucleus, but in affected areas of ALS
Autor:
Alaa Shaban, Janet F. Partridge, Kevin M. Creamer, Olivia L. George, Sreenath Shanker, Godwin Job
Publikováno v:
PLoS Genetics, Vol 6, Iss 10, p e1001174 (2010)
PLoS Genetics
PLoS Genetics
Formation of centromeric heterochromatin in fission yeast requires the combined action of chromatin modifying enzymes and small RNAs derived from centromeric transcripts. Positive feedback mechanisms that link the RNAi pathway and the Clr4/Suv39h1 hi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9, Pp 3307-3314 (2010)
PLoS ONE, Vol 5, Iss 9, Pp 3307-3314 (2010)
BACKGROUND: The multi-subunit eukaryotic initiation factor3 (eIF3) plays a central role in the initiation step of protein synthesis in eukaryotes. One of its large subunits, eIF3b, serves as a scaffold within eIF3 as it interacts with several other s
Autor:
Alicja Nauman, Anna Wojcicka, Agnieszka Piekiełko-Witkowska, Zbigniew Tanski, Piotr Popławski, Hanna Wiszomirska, Joanna Boguslawska
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 10, p e13690 (2010)
PLoS ONE, Vol 5, Iss 10, p e13690 (2010)
BackgroundClear cell renal cell carcinoma (ccRCC) is the most common type of renal cancer. One of the processes disturbed in this cancer type is alternative splicing, although phenomena underlying these disturbances remain unknown. Alternative splici
Autor:
Christof Niehrs, Andrea I. Schäfer, Andriy V. Kubarenko, Alexander N.R. Weber, Yuliya A. Sytnikova
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 1, p e14500 (2011)
PLoS ONE, Vol 6, Iss 1, p e14500 (2011)
Background The Gadd45 proteins play important roles in growth control, maintenance of genomic stability, DNA repair, and apoptosis. Recently, Gadd45 proteins have also been implicated in epigenetic gene regulation by promoting active DNA demethylatio
Autor:
Martin Hammarström, P. Schutz, Wolfram Tempel, R. Collins, Hee-Won Park, L. Holmberg-Schiavone, Martin Högbom, Tobias Karlberg, Susanne van den Berg, Herwig Schüler, Martin Moche, Lari Lehtiö, Ann-Gerd Thorsell
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9 (2010)
PLoS ONE, Vol 5, Iss 9 (2010)
DEAD-box RNA helicases play various, often critical, roles in all processes where RNAs are involved. Members of this family of proteins are linked to human disease, including cancer and viral infections. DEAD-box proteins contain two conserved domain