Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Molecular Biology/Post-Translational Regulation of Gene Expression"'
A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress
Autor:
Thomas J. Begley, Clement T Y Chan, Koli Taghizadeh, Michael S. DeMott, Madhu Dyavaiah, Peter C. Dedon
Publikováno v:
PLoS Genetics
PLoS
PLoS Genetics, Vol 6, Iss 12, p e1001247 (2010)
PLoS
PLoS Genetics, Vol 6, Iss 12, p e1001247 (2010)
Decades of study have revealed more than 100 ribonucleoside structures incorporated as post-transcriptional modifications mainly in tRNA and rRNA, yet the larger functional dynamics of this conserved system are unclear. To this end, we developed a hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b94db48ef5e639862c63195f672d82
http://europepmc.org/articles/PMC3002981
http://europepmc.org/articles/PMC3002981
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14444 (2010)
PLoS ONE
PLoS ONE
The increasing ability to generate large-scale, quantitative proteomic data has brought with it the challenge of analyzing such data to discover the sequence elements that underlie systems-level protein behavior. Here we show that short, linear prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a3fb71876cd78e5acc200b7582629f
http://europepmc.org/articles/PMC3012054?pdf=render
http://europepmc.org/articles/PMC3012054?pdf=render
Autor:
Fernando Bravo-Almonacid, Mirtha M. Flawiá, Héctor N. Torres, Vanina Rodriguez, Briardo Llorente, Guillermo D. Alonso
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14030 (2010)
PLoS ONE
PLoS ONE
Sensory analysis studies are critical in the development of quality enhanced crops, and may be an important component in the public acceptance of genetically modified foods. It has recently been established that odor preferences are shared between hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45805412a8ace90287afa767b3f9e12d
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21103333/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21103333/?tool=EBI
Autor:
Thomas D. Schmittgen, Ramesh Narayanan, Yuriy Gusev, Duane D. Miller, Amanda Jones, Jinmai Jiang, Jeffrey D. Kearbey, James T. Dalton
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 10, p e13637 (2010)
PLoS ONE, Vol 5, Iss 10, p e13637 (2010)
Androgen receptor (AR) function is critical for the development of male reproductive organs, muscle, bone and other tissues. Functionally impaired AR results in androgen insensitivity syndrome (AIS). The interaction between AR and microRNA (miR) sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f36f641426b021d521ee78ac622a8b
http://europepmc.org/articles/PMC2965097
http://europepmc.org/articles/PMC2965097
Autor:
Yaou Zhang, Ling Fang, William W. Du, Jennifer Yang, Minhui Li, Daniel Y. Lee, Albert Y. Yee, Zina Jeyapalan, Tatiana Shatseva, Burton B. Yang
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13599 (2010)
PLoS ONE
PLoS ONE
Background Mature microRNAs (miRNAs) are single-stranded RNAs that regulate post-transcriptional gene expression. In our previous study, we have shown that versican 3′UTR, a fragment of non-coding transcript, has the ability to antagonize miR-199a-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6995e7e4961c8d00db7192f2e82afc16
http://europepmc.org/articles/PMC2963607?pdf=render
http://europepmc.org/articles/PMC2963607?pdf=render
Autor:
Yalin Liao, Bo Lönnerdal
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12976 (2010)
PLoS ONE
PLoS ONE
MicroRNAs play extensive roles in cellular development. Analysis of the microRNA expression pattern during intestinal cell proliferation in early life is likely to unravel molecular mechanisms behind intestinal development and have implications for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6438e00ca7cf036a57b0692efd27f7d
http://europepmc.org/articles/PMC2944884?pdf=render
http://europepmc.org/articles/PMC2944884?pdf=render
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9, p e13005 (2010)
PLoS ONE, Vol 5, Iss 9, p e13005 (2010)
BACKGROUND: Investigation of microRNAs (miRNAs) in obesity, their genetic targets and influence by dietary modulators is of great interest because it may potentially identify novel pathways involved in this complex metabolic disorder and influence fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c856e2f75ab7765d21ce7d88ee61f49
http://europepmc.org/articles/PMC2946340
http://europepmc.org/articles/PMC2946340
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
PLoS ONE
PLoS ONE
The vast landscape of RNA-protein interactions at the heart of post-transcriptional regulation remains largely unexplored. Indeed it is likely that, even in yeast, a substantial fraction of the regulatory RNA-binding proteins (RBPs) remain to be disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347e593dd5f73bb2226ed510d22abad3
http://europepmc.org/articles/PMC2937035?pdf=render
http://europepmc.org/articles/PMC2937035?pdf=render
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 9 (2010)
PLoS Computational Biology
PLoS Computational Biology
Expanded polyglutamine (polyQ) proteins are known to be the causative agents of a number of human neurodegenerative diseases but the molecular basis of their cytoxicity is still poorly understood. PolyQ tracts may impede the activity of the proteasom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48077c408dfa0d9accf88857ca60d591
http://europepmc.org/articles/PMC2944785?pdf=render
http://europepmc.org/articles/PMC2944785?pdf=render
Autor:
Russell Desnoyer, Belinda Willard, Suma Kaveti, Michael Kinter, Sadashiva S. Karnik, Rajaganapathi Jagannathan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9, p e12552 (2010)
PLoS ONE, Vol 5, Iss 9, p e12552 (2010)
Chronic activation of angiotensin II (AngII) type 1 receptor (AT(1)R), a prototypical G protein-coupled receptor (GPCR) induces gene regulatory stress which is responsible for phenotypic modulation of target cells. The AT(1)R-selective drugs reverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d77c4ef30e8cce9caeff135426dc695
http://europepmc.org/articles/PMC2933232
http://europepmc.org/articles/PMC2933232