A Novel Toxoplasma gondii Nuclear Factor TgNF3 Is a Dynamic Chromatin-Associated Component, Modulator of Nucleolar Architecture and Parasite Virulence

Autor: Agnès Hovasse, Christine Schaeffer-Reiss, Alain Van Dorsselaer, Thomas Mouveaux, Alejandro Olguin-Lamas, Stanislas Tomavo, Edwige Madec, Christian Slomianny, Elisabeth Werkmeister, Stéphane Delhaye, Isabelle Callebaut

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 3, p e1001328 (2011)
PLoS Pathogens, Public Library of Science, 2011, 7 (3), pp.e1001328. ⟨10.1371/journal.ppat.1001328⟩
PLoS Pathogens, 2011, 7 (3), pp.e1001328. ⟨10.1371/journal.ppat.1001328⟩

In Toxoplasma gondii, cis-acting elements present in promoter sequences of genes that are stage-specifically regulated have been described. However, the nuclear factors that bind to these cis-acting elements and regulate promoter activities have not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329b799eb81cff83b5f39da58b88ce5b
http://europepmc.org/articles/PMC3068996

Entrapment of viral capsids in nuclear PML cages is an intrinsic antiviral host defense against varicella-zoster virus

Autor: Marvin Sommer, John Perrino, Ann M. Arvin, Armin Baiker, Nandini Sen, Mike Reichelt, Li Wang, Leigh Zerboni, Adel M. Nour

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 2, p e1001266 (2011)

The herpesviruses, like most other DNA viruses, replicate in the host cell nucleus. Subnuclear domains known as promyelocytic leukemia protein nuclear bodies (PML-NBs), or ND10 bodies, have been implicated in restricting early herpesviral gene expres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021fc1a6af8b87b11ec11bd42ebc5937
https://pubmed.ncbi.nlm.nih.gov/21304940

Gadd45a is an RNA binding protein and is localized in nuclear speckles

Autor: Christof Niehrs, Andrea I. Schäfer, Andriy V. Kubarenko, Alexander N.R. Weber, Yuliya A. Sytnikova

Publikováno v: PLoS ONE
PLoS ONE, Vol 6, Iss 1, p e14500 (2011)

Background The Gadd45 proteins play important roles in growth control, maintenance of genomic stability, DNA repair, and apoptosis. Recently, Gadd45 proteins have also been implicated in epigenetic gene regulation by promoting active DNA demethylatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a433ed48a1965eda66bd8fc342325f
https://pubmed.ncbi.nlm.nih.gov/21249130

Phosphorylated nucleolin interacts with translationally controlled tumor protein during mitosis and with Oct4 during interphase in ES cells

Autor: Helena Johansson, Stina Simonsson, Frida Svensson, Rikard Runnberg, Tomas Simonsson

Publikováno v: PLoS ONE, Vol 5, Iss 10, p e13678 (2010)
PLoS ONE

Background Reprogramming of somatic cells for derivation of either embryonic stem (ES) cells, by somatic cell nuclear transfer (SCNT), or ES-like cells, by induced pluripotent stem (iPS) cell procedure, provides potential routes toward non-immunogeni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec76e39f8fecf81f817d069dafc1bf52
http://europepmc.org/articles/PMC2965110?pdf=render

Initial genomics of the human nucleolus

Autor: Gernot Längst, Joaquín Dopazo, Bálint Péterfia, Thomas Cremer, David Montaner, Javier Santoyo-Lopez, Ana Conesa, Attila Németh, Ignacio Medina, Irina Solovei

Publikováno v: PLoS Genetics
PLoS Genetics, Vol 6, Iss 3, p e1000889 (2010)
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname

We report for the first time the genomics of a nuclear compartment of the eukaryotic cell. 454 sequencing and microarray analysis revealed the pattern of nucleolus-associated chromatin domains (NADs) in the linear human genome and identified differen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08bbb02377ddcaebd9235d98d16f3af6
https://pubmed.ncbi.nlm.nih.gov/20361057