Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Molecular Biology/DNA Replication"'
Autor:
Weinreich M; Genome Integrity and Tumorigenesis Laboratory, Van Andel Institute, Grand Rapids, Michigan 49503, USA.
Publikováno v:
Nature [Nature] 2015 Mar 26; Vol. 519 (7544), pp. 418-9.
Publikováno v:
Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005..
In this paper, we introduce a new method of modeling tool for a biological process -central dogma. The deterministic Boolean Network (DBN) is used as a modeling tool of the whole process, which enables us to simulate, analyze, and manipulate (in the
Conference
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Autor:
Joana Sequeira-Mendes, Neil Brockdorff, Derek Huntley, Anwyn Apedaile, Ramon Diaz-Uriarte, María Gómez
Publikováno v:
PLoS Genetics, Vol 5, Iss 4, p e1000446 (2009)
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
PLoS Genetics
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
PLoS Genetics
Genomic mapping of DNA replication origins (ORIs) in mammals provides a powerful means for understanding the regulatory complexity of our genome. Here we combine a genome-wide approach to identify preferential sites of DNA replication initiation at 0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df81c6e3c29e56f4fe510355b93cefbd
https://ora.ox.ac.uk/objects/uuid:eeed55a8-5a1a-4bf1-ac8d-2ec3cc6fc8af
https://ora.ox.ac.uk/objects/uuid:eeed55a8-5a1a-4bf1-ac8d-2ec3cc6fc8af
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1001328 (2011)
PLoS Genetics
PLoS Genetics
Asymmetrical segregation of differentiated sister chromatids is thought to be important for cellular differentiation in higher eukaryotes. Similarly, in fission yeast, cellular differentiation involves the asymmetrical segregation of a chromosomal im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa80bb9a0b9af69d4f89730a0bc9798
http://wrap.warwick.ac.uk/34580/1/WRAP_Sayrac_Identification_Novel_Type_.pdf
http://wrap.warwick.ac.uk/34580/1/WRAP_Sayrac_Identification_Novel_Type_.pdf
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1001355 (2011)
PLoS Genetics
PLoS Genetics
SUMO conjugation is a key regulator of the cellular response to DNA replication stress, acting in part to control recombination at stalled DNA replication forks. Here we examine recombination-related phenotypes in yeast mutants defective for the SUMO
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1001339 (2011)
PLoS Genetics
PLoS Genetics
Repetitive DNA elements are mutational hotspots in the genome, and their instability is linked to various neurological disorders and cancers. Although it is known that expanded trinucleotide repeats can interfere with DNA replication and repair, the
Autor:
Maria Patrizia Somma, Ferdinando Di Cunto, Paolo Provero, C. Damasco, Maurizio Gatti, Antonio Lembo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 2, p e14737 (2011)
PloS one 6 (2011): e14737. doi:10.1371/journal.pone.0014737
info:cnr-pdr/source/autori:Damasco C.; Lembo A.; Somma MP.; Gatti M.; Di Cunto F.; and Provero P./titolo:A signature inferred from Drosophila mitotic genes predicts survival of breast cancer patients/doi:10.1371%2Fjournal.pone.0014737/rivista:PloS one/anno:2011/pagina_da:e14737/pagina_a:/intervallo_pagine:e14737/volume:6
PLoS ONE, Vol 6, Iss 2, p e14737 (2011)
PloS one 6 (2011): e14737. doi:10.1371/journal.pone.0014737
info:cnr-pdr/source/autori:Damasco C.; Lembo A.; Somma MP.; Gatti M.; Di Cunto F.; and Provero P./titolo:A signature inferred from Drosophila mitotic genes predicts survival of breast cancer patients/doi:10.1371%2Fjournal.pone.0014737/rivista:PloS one/anno:2011/pagina_da:e14737/pagina_a:/intervallo_pagine:e14737/volume:6
INTRODUCTION: The classification of breast cancer patients into risk groups provides a powerful tool for the identification of patients who will benefit from aggressive systemic therapy. The analysis of microarray data has generated several gene expr
Autor:
Danae Schulz, Robert S. Lahue, Catherine H. Freudenreich, Lionel Gellon, Lauren Verra, David F. Razidlo, Olive Gleeson
Publikováno v:
PLoS Genetics, Vol 7, Iss 2, p e1001298 (2011)
PLoS Genetics
PLoS Genetics
Expansion of DNA trinucleotide repeats causes at least 15 hereditary neurological diseases, and these repeats also undergo contraction and fragility. Current models to explain this genetic instability invoke erroneous DNA repair or aberrant replicati