Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Moleculaire afweer"'
Autor:
van Dijk, Albert, Guabiraba, Rodrigo, Bailleul, Geoffrey, Schouler, Catherine, Haagsman, Henk P, Lalmanach, Anne-Christine, Moleculaire afweer
Publikováno v:
Molecular Immunology, 157, 53. Elsevier
Divergent evolution for more than 310 million years has resulted in an avian immune system that is complex and more compact than that of primates, sharing much of its structure and functions. Not surprisingly, well conserved ancient host defense mole
Autor:
Harten, Roel M. van, Bokhoven, Johanna L.M. Tjeerdsma-van, Greeff, Astrid de, Balhuizen, Melanie D., Dijk, Albert van, Veldhuizen, Edwin J.A., Haagsman, Henk P., Scheenstra, Maaike R., Moleculaire afweer, dI&I I&I-3, Immunologie
Publikováno v:
Journal of Advanced Research, Vol 36, Iss, Pp 101-112 (2022)
Journal of Advanced Research 36 (2022)
Journal of Advanced Research, 36, 101. Cairo University
Journal of Advanced Research
Journal of Advanced Research, 36, 101-112
Journal of Advanced Research 36 (2022)
Journal of Advanced Research, 36, 101. Cairo University
Journal of Advanced Research
Journal of Advanced Research, 36, 101-112
Graphical abstract
Highlights • D-CATH-2 has strong antimicrobial activities towards multiple S.suis strains. • D-CATH-2 ameliorates macrophage function. • DCATH-2 binds LTA. • DCATH-2 has prophylactic effect against S. suis infection in
Highlights • D-CATH-2 has strong antimicrobial activities towards multiple S.suis strains. • D-CATH-2 ameliorates macrophage function. • DCATH-2 binds LTA. • DCATH-2 has prophylactic effect against S. suis infection in
Autor:
Verheije, M. Hélène, Coorens, Maarten, Weerts, Erik A.W.S., Berends, Alinda J., van Harten, Roel M., Angel, Marloes, Kooij, Jannetje, Ordonez, Soledad R., van Beurden, Steven J., van Dijk, Albert, Haagsman, Henk P., Veldhuizen, Edwin J.A., dPB I&I, VP pathologie, LS Moleculaire Afweer, VPDC pathologie, Afd Pharmacology, dI&I I&I-1, Moleculaire afweer, dI&I I&I-3, LS Pathologie, Immunologie
Publikováno v:
Peptide Science, 114(1), 1. John Wiley and Sons Inc.
Avian infectious bronchitis (IB) is a highly contagious disease caused by infectious bronchitis virus (IBV), a coronavirus of domestic fowl. IB is a major concern in the poultry industry, causing worldwide economic losses through decreased egg produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f952963cddc34a0744d42afcd66583
https://dspace.library.uu.nl/handle/1874/423963
https://dspace.library.uu.nl/handle/1874/423963
Autor:
Pérez-Ortega, Jesús, Van Harten, Roel M, Van Boxtel, Ria, Plisnier, Michel, Louckx, Marc, Ingels, Dominique, Haagsman, Henk P, Tommassen, Jan, Sub Molecular Microbiology, Moleculaire afweer, dI&I I&I-3, Molecular Microbiology
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 1452-1468 (2021)
Virulence
article-version (VoR) Version of Record
Virulence, 12(1), 1452. Landes Bioscience
Virulence
article-version (VoR) Version of Record
Virulence, 12(1), 1452. Landes Bioscience
Whole-cell vaccines against Gram-negative bacteria commonly display high reactogenicity caused by the endotoxic activity of lipopolysaccharide (LPS), one of the major components of the bacterial outer membrane. Underacylation of the lipid A moiety of
Autor:
Le Guern, Florent, Gaucher, Anne, Cosentino, Gina, Lagune, Marion, Haagsman, Henk P, Roux, Anne-Laure, Prim, Damien, Rottman, Martin, Moleculaire afweer
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 16067
International Journal of Molecular Sciences, 23(24). MDPI AG
International Journal of Molecular Sciences, 23(24). MDPI AG
Establishing the rapid and accurate diagnosis of sepsis is a key component to the improvement of clinical outcomes. The ability of analytical platforms to rapidly detect pathogen-associated molecular patterns (PAMP) in blood could provide a powerful
Autor:
van Eijk, Martin, van Dijk, Albert, van der Ent, Cornelis K, Arets, Hubertus G M, Breukink, Eefjan, van Os, Nico, Adrichem, Roy, van der Water, Sven, Gomez, Rita Lino, Kristensen, Maartje, Hessing, Martin, Jekhmane, Shehrazade, Weingarth, Markus, Veldhuizen, Ruud A W, Veldhuizen, Edwin J A, Haagsman, Henk P, LS Moleculaire Afweer, Moleculaire afweer, dI&I I&I-3, Sub Membrane Biochemistry & Biophysics, Sub NMR Spectroscopy, Immunologie
Publikováno v:
Biochimica et Biophysica Acta-General Subjects, 1865(9). Elsevier
Background Antimicrobial peptides are considered potential alternatives for antibiotics. Here we describe the antibacterial properties of a family of novel cathelicidin-related (CR-) peptides, which we named PepBiotics, against bacteria typically pre
Autor:
Peng, Lianci, Lu, Yi, Tian, Hongliang, Jia, Kaixiang, Tao, Qi, Li, Gang, Wan, Chao, Ye, Chao, Veldhuizen, Edwin J A, Chen, Hongwei, Fang, Rendong, Moleculaire afweer, Immunologie, dI&I I&I-3, LS Moleculaire Afweer
Publikováno v:
Developmental and Comparative Immunology, 131, 1. Elsevier Limited
Cathelicidins have antimicrobial and immunomodulatory activities. Previous studies have shown that chicken cathelicidin-2 (CATH-2) exerts strong anti-inflammatory activity through LPS neutralization. However, it is still unclear whether other intrace
Autor:
van Dijk, Albert, Anten, Jennifer, Bakker, Anne, Evers, Noah, Hoekstra, Anna T, Chang, Jung-Chin, Scheenstra, Maaike R, Veldhuizen, Edwin J A, Netea, Mihai G, Berkers, Celia R, Haagsman, Henk P, Moleculaire afweer, Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre for Biomolecular Research, Pathobiologie, Immunologie, Veterinaire biochemie, Sub Biomol.Mass Spectrometry & Proteom.
Publikováno v:
Frontiers in Immunology, 13, 1. Frontiers Media S.A.
Frontiers in Immunology, 13
Frontiers in Immunology, 13
Trained innate immunity can be induced in human macrophages by microbial ligands, but it is unknown if exposure to endogenous alarmins such as cathelicidins can have similar effects. Previously, we demonstrated sustained protection against infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feabe9791fe88b922ddcdf974f42a6ef
https://dspace.library.uu.nl/handle/1874/422314
https://dspace.library.uu.nl/handle/1874/422314
Autor:
Scheenstra, Maaike R, van Harten, Roel M, Veldhuizen, Edwin J A, Haagsman, Henk P, Coorens, Maarten, Moleculaire afweer, dI&I I&I-3, LS Moleculaire Afweer
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, 11. Frontiers Media S.A.
Frontiers in Immunology
Frontiers in Immunology, 11. Frontiers Media S.A.
Frontiers in Immunology
Cathelicidins are short cationic peptides that are part of the innate immune system. At first, these peptides were studied mostly for their direct antimicrobial killing capacity, but nowadays they are more and more appreciated for their immunomodulat
Autor:
Shukla, Rhythm, Medeiros-Silva, João, Parmar, Anish, Vermeulen, Bram J A, Das, Sanjit, Paioni, Alessandra Lucini, Jekhmane, Shehrazade, Lorent, Joseph, Bonvin, Alexandre M J J, Baldus, Marc, Lelli, Moreno, Veldhuizen, Edwin J A, Breukink, Eefjan, Singh, Ishwar, Weingarth, Markus, Sub NMR Spectroscopy, Sub Membrane Biochemistry & Biophysics, Moleculaire afweer, dI&I I&I-3
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications, 11(1). Nature Publishing Group
Nature Communications
Nature Communications, 11(1). Nature Publishing Group
Nature Communications
The natural antibiotic teixobactin kills pathogenic bacteria without detectable resistance. The difficult synthesis and unfavourable solubility of teixobactin require modifications, yet insufficient knowledge on its binding mode impedes the hunt for