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Failure to down-regulate intragraft cytokine mRNA expression shortly after clinical heart transplantation is associated with high incidence of acute rejection

Autor: de Groot-Kruseman, H A, Baan, C C, Loonen, E H, Mol, W M, Niesters, H G, Maat, A P, Balk, A H, Weimar, W

Publikováno v: Journal of Heart and Lung Transplantation, 20(5), 503-510. ELSEVIER SCIENCE INC

BACKGROUND: Brain-death, ischemia and reperfusion damage have been implicated as initial factors that lead to a cascade of immunologic events that result in allograft rejection in experimental animals. Cytokines are thought to play a central role in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::47b691d50fa9d576e9af74f13972065e
https://research.rug.nl/en/publications/a0c7e09c-64d3-4a73-bc0e-dfc84b26a4ce

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Intragraft platelet-derived growth factor-alpha and transforming growth factor-beta1 during the development of accelerated graft vascular disease after clinical heart transplantation

Autor: de Groot-Kruseman, H A, Baan, C C, Mol, W M, Niesters, H G, Maat, A P, Balk, A H, Weimar, W

Publikováno v: Transplant immunology, 7(4), 201-205. Elsevier

This study was to determine whether the growth factors platelet-derived growth factor-alpha (PDGF-alpha) and transforming growth factor-beta1 (TGF-beta1) contribute to the development of graft vascular disease (GVD) after clinical heart transplantati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::49909ab18cfafb5addd2e59f8ba64778
https://research.rug.nl/en/publications/3ec0f860-0fb8-415d-9951-72bfd01ed5d2

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Increased intragraft IL-15 mRNA expression after liver transplantation

Autor: Baan, C. C., Hubert Niesters, Metselaar, H. J., Mol, W. M., Loonen, E. H. M., Zondervan, P. E., Tilanus, H. W., Ijzermans, J. M. N., Schalm, S. W., Weimar, W.

Publikováno v: Clinical Transplantation, 12(3), 212-8. Wiley
Scopus-Elsevier

To study T-cell/macrophage interactions at the molecular level in clinical allograft rejection, we measured intragraft mRNA expression of the T-cell derived cytokine IL-2 and the macrophage derived chemokine IL-15, a novel cytokine associated with T-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ac63d7919b78bff358c83ed6b2bcbded
https://research.rug.nl/en/publications/4afd37aa-3827-4e94-9026-131b3de8af13

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Intragraft IL-4 mRNA expression is associated with down-regulation of liver graft rejection

Autor: Baan, C. C., Metselaar, H. J., Mol, W. M., Tilanus, H. W., Ijzermans, J. M. N., Zondervan, P. E., Schalm, S. W., Hubert Niesters, Weimar, W.

Publikováno v: Clinical Transplantation, 10(6 Pt 1), 542-549. Wiley
Scopus-Elsevier

The mechanism underlying spontaneously resolving allograft rejection following clinical liver transplantation is unidentified. In this process, immunoregulatory T helper (Th)-2 cytokines like IL-4, often identified with down-regulation of the Th1-dep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a54c1ce87bf6f50d750222933a2b92ba
https://research.rug.nl/en/publications/c16f1ed0-6bd3-41e0-88ce-24532f233051

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Eicosanoid levels in bronchoalveolar lavage fluid of young female smokers and non-smokers.

Autor: ZIJLSTRA, F. J., VINCENT, J. E., MOL, W. M., HOOGSTEDEN, H. C., HAL, P. Th. W. VAN, JONGEJA, R. C.

Publikováno v: European Journal of Clinical Investigation; May1992, Vol. 22 Issue 5, p301-306, 6p

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