Zobrazeno 1 - 10 of 38 pro vyhledávání: '"Mojmir Mach"'
1
Akademický článek
Evaluation of New Approaches to Depression Treatment Using an Animal Model of Pharmacoresistant Depression
Autor: Alexandra Zvozilova, Stanislava Bukatova, Romana Koprdova, Mojmir Mach
Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 10, p 5265 (2024)
Depression is emerging as the predominant psychiatric disorder globally. Despite the wide availability of antidepressants, up to 30% of patients exhibit poor response to treatment, falling into the category of treatment-resistant depression (TRD). Th
Externí odkaz: https://doaj.org/article/c86879522f1f4cfcabb7a546e5707fa1
Zobrazit plný text záznamu
2
Akademický článek
Effect of a New Substance with Pyridoindole Structure on Adult Neurogenesis, Shape of Neurons, and Behavioral Outcomes in a Chronic Mild Stress Model in Rats
Autor: Alexandra Zvozilova, Alexandra Reichova, Mojmir Mach, Jan Bakos, Romana Koprdova
Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 2, p 845 (2024)
Despite an accumulating number of studies, treatments for depression are currently insufficient. Therefore, the search for new substances with antidepressant potential is very important. In this study, we hypothesized that treatment with a newly synt
Externí odkaz: https://doaj.org/article/fd47490fc30e4e3f8fe05482e65a8e14
Zobrazit plný text záznamu
3
Akademický článek
Combined In Silico, Ex Vivo, and In Vivo Assessment of L-17, a Thiadiazine Derivative with Putative Neuro- and Cardioprotective and Antidepressant Effects
Autor: Alexey Sarapultsev, Pavel Vassiliev, Daniil Grinchii, Alexander Kiss, Mojmir Mach, Jana Osacka, Alexandra Balloova, Ruslan Paliokha, Andrey Kochetkov, Larisa Sidorova, Petr Sarapultsev, Oleg Chupakhin, Maxim Rantsev, Alexander Spasov, Eliyahu Dremencov
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 24, p 13626 (2021)
Depression associated with poor general medical condition, such as post-stroke (PSD) or post-myocardial infarction (PMID) depression, is characterized by resistance to classical antidepressants. Special treatment strategies should thus be developed f
Externí odkaz: https://doaj.org/article/8779cb30388f49e9bc7d2393fba8e940
Zobrazit plný text záznamu
4
Akademický článek
Electrophysiology and Behavioral Assessment of the New Molecule SMe1EC2M3 as a Representative of the Future Class of Triple Reuptake Inhibitors
Autor: Romana Koprdova, Kristina Csatlosova, Barbora Durisova, Eszter Bogi, Magdalena Majekova, Eliyahu Dremencov, Mojmir Mach
Publikováno v: Molecules, Vol 24, Iss 23, p 4218 (2019)
SMe1EC2M3 is a pyridoindole derivative related to the neuroleptic drug carbidine. Based on the structural similarities of SMe1EC2M3 and known serotonin (5-HT), norepinephrine, and dopamine reuptake inhibitors, we hypothesized that this compound may a
Externí odkaz: https://doaj.org/article/c4a5c862235741f3aa01bb2bb538899a
Zobrazit plný text záznamu
6
Alterations in myocardial connexin-43 and matrix metalloproteinase-2 signaling in response to pregnancy and oxygen deprivation of Wistar rats: a pilot study
Autor: Barbara Szeiffova Bacova, Narcis Tribulova, Tamara Egan Benova, Lucia Kamocsaiova, Karel Frimmel, Mojmir Mach, Miroslav Barancik, Matus Sykora, Eduard Ujhazy
Publikováno v: Canadian Journal of Physiology and Pharmacology. 97:829-836
Two important aspects of cardiac adaptive response to pregnancy have been studied in normal as well as hypoxic conditions: (1) intercellular signaling mediated by myocardial connexin-43 (Cx43) that is crucial to synchronize heart function; (2) extrac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fcce1d2dc9a1cbb1a563a255aaff39d
https://doi.org/10.1139/cjpp-2018-0740
Zobrazit plný text záznamu
7
Effects of venlafaxine and chronic unpredictable stress on behavior and hippocampal neurogenesis of rat dams
Autor: Kristina, Belovicova, Eszter, Bogi, Romana, Koprdova, Eduard, Ujhazy, Mojmir, Mach, Michal, Dubovicky
Publikováno v: Neuro endocrinology letters. 38(1)
Epidemiological studies strongly support the theory that stressful life events play an important role in the etiology of depression. The mechanism of chronic stress induced depression involves a number of systems. Chronic stress represents a serious
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c2a1982ef3bfc7b4c7619e8c4e42cfa
https://pubmed.ncbi.nlm.nih.gov/28456144
Zobrazit plný text záznamu
8
Teratological study of the herbicide 4-chloro-2-methylphenoxyacetic acid in rabbits
Autor: Eduard Ujházy, Michal Dubovický, Sadlonová I, Múcková M, Flaskárová E, Mojmir Mach
Publikováno v: Journal of Applied Toxicology. 26:368-373
4-Chloro-2-methylphenoxyacetic acid (MCPA) is an aryloxyacetic acid derivative categorised as a plant hormone herbicide. The aim of the study was to evaluate the effect of MCPA on pregnant females and the prenatal development of rabbits. The substanc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202706fc5a7bfc0f9307815dbe42b8ad
https://doi.org/10.1002/jat.1151
Zobrazit plný text záznamu
9
Behavioral changes after acetylcholinesterase inhibition with physostigmine in mice
Autor: William A. Price, Mojmir Mach, Robert D. Grubbs, James B. Lucot, Sara Paton
Publikováno v: Pharmacology Biochemistry and Behavior. 79:533-540
The effect of the central and peripheral acetylcholinesterase (AChE) inhibitor, physostigmine (PHY), was examined on spatial memory using a water maze, motor activity as well as acoustic startle response (ASR) and prepulse inhibition (PPI) in C57BL/6
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fffebc9573c4d7e27f475956db71ec4
https://doi.org/10.1016/j.pbb.2004.09.009
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje