Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Mojgan Najafzadeh"'
Autor:
Mojgan Najafzadeh, Parisa Naeem, Nader Ghaderi, Shohreh Jafarinejad, Zahra Karimi, Mehran Ghaderi, Pouria Akhbari, Rojan Ghaderi, Pedram Farsi, Andrew Wright, Diana Anderson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract This study compared the expression of TP53 in lymphocytes from malignant melanoma (MM) patients with positive sentinel nodes to healthy controls (HCs) following exposure to various doses of UVA radiation. The Lymphocyte Genome Sensitivity (L
Externí odkaz:
https://doaj.org/article/d50d95bd1b81476387df776fe8e9a2be
Autor:
Maysa Alhawmdeh, Mohammad Isreb, Abid Aziz, Badie K. Jacob, Diana Anderson, Mojgan Najafzadeh
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Lung cancer is one of the main causes of death worldwide. Published data show the use of interferons (IFNs) in treating lung tumours. IFNs also have potential for their antiproliferative, antiangiogenic, immunoregulatory and proapoptotic effects. IFN
Externí odkaz:
https://doaj.org/article/82dade1da1df4fc69ba7c39d97d2e930
Autor:
Diana Anderson, Mojgan Najafzadeh, Charmaine Normington, Badie Jacob, Mohammad Isreb, Rajendran Gopalan
Publikováno v:
Frontiers in Molecular Biosciences, Vol 3 (2016)
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX enzyme activity which affects the inflammatory response. Inflammation is associated with increasing cancer incidence. Pre-clinical and clinical studies have shown that NSAID treatment could c
Externí odkaz:
https://doaj.org/article/539d80efeaee4ab3a83139383afd824d
Autor:
Mojgan Najafzadeh, Badie Jacobe
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX enzyme activity, a significant mechanism of action of NSAIDs. Inflammation is associated with increasing cancer incidence. Recent pre-clinical and clinical studies have shown that NSAID treat
Externí odkaz:
https://doaj.org/article/3496086f2f7449468196b840f70b62ca
Autor:
Mojgan Najafzadeh, Parisa Naeem, Nader Ghaderi, Shohreh Jafarinejad, Zahra Karimi, Mehran Ghaderi, Pouria Akhbari, Rojan Ghaderi, Pedram Farsi, Andrew Wright, Diana Anderson
This study aimed to evaluate the expression of the P53 gene following exposure to varying doses of UVA radiation, using lymphocytes as surrogates. Lymphocytes from malignant melanoma (MM) patients (n = 20) with positive sentinel nodes were compared t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69a7a34290cf6ff42ac2d994c77e1775
https://doi.org/10.21203/rs.3.rs-2540105/v1
https://doi.org/10.21203/rs.3.rs-2540105/v1
Autor:
Parisa Naeem, Adi Baumgartner, Nader Ghaderi, Farshid Sefat, Maysa Alhawamdeh, Saeed Heidari, Fanila Shahzad, Karthic Swaminathan, Pouria Akhbari, Mohammad Isreb, Diana Anderson, Andrew Wright, Mojgan Najafzadeh
Publikováno v:
Journal of Cellular and Molecular Medicine, 2023, Vol.27(2) [Peer Reviewed Journal]
Incidence of Malignant Melanoma has become the 5th in the UK. To date, the major anticancer therapeutics include cell therapy, immunotherapy, gene therapy and nanotechnology-based strategies. Recently, extracellular vesicles, especially exosomes, hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e458689b17d5f809de276a84d4c8315
https://pubmed.ncbi.nlm.nih.gov/36545841
https://pubmed.ncbi.nlm.nih.gov/36545841
Autor:
Mohammad Isreb, Badie K. Jacob, Maysa Alhawmdeh, Abid Aziz, Mojgan Najafzadeh, Diana Anderson
Publikováno v:
ERJ Open Research
article-version (VoR) Version of Record
ERJ Open Research, Vol 7, Iss 3 (2021)
article-version (VoR) Version of Record
ERJ Open Research, Vol 7, Iss 3 (2021)
Lung cancer is one of the main causes of death worldwide. Published data show the use of interferons (IFNs) in treating lung tumours. IFNs also have potential for their antiproliferative, antiangiogenic, immunoregulatory and proapoptotic effects. IFN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79d088f524c89d3d979c39dac115ba1
https://doi.org/10.1183/23120541.00555-2020
https://doi.org/10.1183/23120541.00555-2020
Autor:
Lisa Newton, Mohammad Isreb, Mojgan Najafzadeh, Diana Anderson, Shabana Akhtar, Rajendran C. Gopalan
Publikováno v:
Archives of Toxicology
Evading apoptosis and chemo-resistance are considered as very important factors which help tumour progression and metastasis. Hence, to overcome chemo-resistance, there is an urgent requirement for emergence of more effective treatment options. Myric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947986af1fcd821778e19214693c6b09
https://doi.org/10.1007/s00204-020-02938-5
https://doi.org/10.1007/s00204-020-02938-5
Autor:
Mohammad Isreb, Shabana Akhtar, Lisa Newton, Rajendran C. Gopalan, Mojgan Najafzadeh, Diana Anderson
Publikováno v:
Archives of Toxicology
2-Amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) is a central dietary mutagen, produced when proteinaceous food is heated at very high temperatures potentially causing DNA strand breaks. This study investigates the protective potential of a we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c8fcc926eb7c88e1aa1e01c6fb61d3
https://doi.org/10.1007/s00204-020-02754-x
https://doi.org/10.1007/s00204-020-02754-x
Autor:
Lisa Newton, Mohammad Isreb, Rajendran C. Gopalan, Mojgan Najafzadeh, Diana Anderson, Shabana Akhtar
Publikováno v:
Archives of Toxicology
We investigated the protective role of myricetin bulk and nanoforms, against reactive oxygen species (ROS)-induced oxidative stress caused by hydrogen peroxide and tertiary-butyl hydro peroxide in lymphocytes in vitro from healthy individuals and tho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0727dcd96c6517e321f53c3338deb6a
https://doi.org/10.1007/s00204-020-02688-4
https://doi.org/10.1007/s00204-020-02688-4