Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mojgan Hadian"'
Autor:
Deniz Eris, Pravin Patil, Matthew Groves, M. Sharpe, Meitian Wang, Mojgan Hadian, Rick Oerlemans, Alexander Dömling, Shabnam Shaabani, Fandi Sutanto
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International ed. in English), 60(33), 18231-18239. WILEY-V C H VERLAG GMBH
Angewandte Chemie (International ed. in English), 60(33), 18231-18239. WILEY-V C H VERLAG GMBH
Protein crystallography (PX) is widely used to drive advanced stages of drug optimization or to discover medicinal chemistry starting points by fragment soaking. However, recent progress in PX could allow for a more integrated role into early drug di
Autor:
Ali Alipour Najmi, Elchin Jafariyeh‐Yazdi, Mojgan Hadian, Jos Hermans, Rainer Bischoff, Jun Yue, Alexander Dömling, Arne Wittstock, Hjalmar P. Permentier
Publikováno v:
ChemMedChem, 17(11):e202200040. WILEY-V C H VERLAG GMBH
A novel method for the selective catalytic N-dealkylation of drug molecules on a nanoporous gold (NPG) catalyst producing valuable N-dealkylated metabolites and intermediates is described. Drug metabolites are important chemical entities at every sta
Autor:
Harry Boltz, Pravin Patil, Svitlana V. Shishkina, Alexander Dömling, Mojgan Hadian, Shabnam Shaabani
Publikováno v:
Green Chemistry, 22(8), 2459-2467. ROYAL SOC CHEMISTRY
Small molecule synthesis is equally important for materials and pharmaceuticals. However, the traditional approach performed in pharmaceutical R&D including maintenance of million-sized libraries and optimization synthesis of hundreds or even thousan