Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Mojgan Djavaheri Mergny"'
Publikováno v:
Cell Stress, Vol 8, Pp 51-55 (2024)
In a recent issue in Nature Cell Biology, Sung Min Son et al. unveil a novel layer in the regulation of the mTORC1/autophagy axis by EP300 which can undergo nucleocytoplasmic shuttling in response to alterations in nutrient availability. The study hi
Externí odkaz:
https://doaj.org/article/ca94fec28cf44ffaa9fcbb29eb322eba
Autor:
Gerasimos Anagnostopoulos, Ester Saavedra, Flavia Lambertucci, Omar Motiño, Jordan Dimitrov, David Roiz-Valle, Victor Quesada, Karla Alvarez-Valadez, Hui Chen, Allan Sauvat, Yan Rong, Uxía Nogueira-Recalde, Sijing Li, Léa Montégut, Mojgan Djavaheri-Mergny, Maria Castedo, Carlos Lopez-Otin, Maria Chiara Maiuri, Isabelle Martins, Guido Kroemer
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-11 (2024)
Abstract Acyl-CoA binding protein (ACBP) encoded by diazepam binding inhibitor (DBI) is an extracellular inhibitor of autophagy acting on the gamma-aminobutyric acid A receptor (GABAAR) γ2 subunit (GABAARγ2). Here, we show that lipoanabolic diets c
Externí odkaz:
https://doaj.org/article/6156a26a97494404ab21b5b9e7b5c530
Publikováno v:
Cells, Vol 12, Iss 3, p 498 (2023)
Autophagy is a catabolic lysosomal-dependent pathway involved in the degradation of cellular materials, supplying precursor compounds and energy for macromolecule synthesis and metabolic needs [...]
Externí odkaz:
https://doaj.org/article/e0a1f66da4144e58a8cae8f4d297e0b7
Autor:
Wencan He, Lamia Azzi-Martin, Valérie Velasco, Philippe Lehours, Pierre Dubus, Mojgan Djavaheri-Mergny, Armelle Ménard
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009320 (2021)
Humans are frequently exposed to bacterial genotoxins of the gut microbiota, such as colibactin and cytolethal distending toxin (CDT). In the present study, whole genome microarray-based identification of differentially expressed genes was performed
Externí odkaz:
https://doaj.org/article/5c8685e08cc747848f57097252ae7e29
Autor:
Lucille Ferret, Karla Alvarez-Valadez, Jennifer Rivière, Alexandra Muller, Natalia Bohálová, Luo Yu, Lionel Guittat, Vaclav Brázda, Guido Kroemer, Jean-Louis Mergny, Mojgan Djavaheri-Mergny
Publikováno v:
Autophagy. :1-15
Autor:
Kelly Airiau, Pierre Vacher, Olivier Micheau, Valerie Prouzet-Mauleon, Guido Kroemer, Mohammad Amin Moosavi, Mojgan Djavaheri-Mergny
Publikováno v:
Cells, Vol 11, Iss 1, p 57 (2021)
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively kills various cancer cell types, but also leads to the activation of signaling pathways that favor resistance to cell death. Here, we investigated the as yet unknown roles of
Externí odkaz:
https://doaj.org/article/28c735ad386d434385fbcd4ebe88d03b
Autor:
Lamia Azzi-Martin, Wencan He, Christelle Péré-Védrenne, Victoria Korolik, Chloé Alix, Martina Prochazkova-Carlotti, Jean-Luc Morel, Emilie Le Roux-Goglin, Philippe Lehours, Mojgan Djavaheri-Mergny, Christophe F Grosset, Christine Varon, Pierre Dubus, Armelle Ménard
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1007921 (2019)
Humans are frequently exposed to bacterial genotoxins involved in digestive cancers, colibactin and Cytolethal Distending Toxin (CDT), the latter being secreted by many pathogenic bacteria. Our aim was to evaluate the effects induced by these genotox
Externí odkaz:
https://doaj.org/article/20e8c17129c44800b4b96d42829fd2f5
Autor:
Faten Merhi, Karla Alvarez-Valadez, Jenifer Trepiana, Claire Lescoat, Alexis Groppi, Jean-William Dupuy, Pierre Soubeyran, Guido Kroemer, Pierre Vacher, Mojgan Djavaheri-Mergny
Publikováno v:
Cells, Vol 10, Iss 12, p 3364 (2021)
Calcium ions (Ca2+) play important and diverse roles in the regulation of autophagy, cell death and differentiation. Here, we investigated the impact of Ca2+ in regulating acute promyelocytic leukemia (APL) cell fate in response to the anti-cancer ag
Externí odkaz:
https://doaj.org/article/176368e73312476792edf20a92c76fa8
Autor:
Mojgan Djavaheri-Mergny, Patrice Codogno, Kevin M. Ryan, Gérard Pierron, Sylvie Souquère, Lisandra Ribeiro Dos Santos, Amélie Borges, Séverine Lorin
Supplementary Figure 2 from c-Jun NH2-Terminal Kinase Activation Is Essential for DRAM-Dependent Induction of Autophagy and Apoptosis in 2-Methoxyestradiol–Treated Ewing Sarcoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a7c79740fe9ff078c4a02ce2185bd9
https://doi.org/10.1158/0008-5472.22379231.v1
https://doi.org/10.1158/0008-5472.22379231.v1
Autor:
Nathalie Andrieu-Abadie, Thierry Levade, Patrice Codogno, Chantal Bauvy, Mojgan Djavaheri-Mergny, Virginie Garcia, Sonia-Caroline Sorli, Virginie Albinet, Carmen Bedia, Blandine Kedjouar, Paul P. Van Veldhoven, Sandra Colié
Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid metabolite involved in cancer development through stimulation of cell survival, proliferation, migration, and angiogenesis. Irreversible degradation of S1P is catalyzed by S1P lyase (SPL). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a4614473e780b67fbe0ccfeacac719d
https://doi.org/10.1158/0008-5472.c.6500387
https://doi.org/10.1158/0008-5472.c.6500387