Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mojca Mattiazzi Usaj"'
Autor:
Anastasia Razdaibiedina, Alexander Brechalov, Helena Friesen, Mojca Mattiazzi Usaj, Myra Paz David Masinas, Harsha Garadi Suresh, Kyle Wang, Charles Boone, Jimmy Ba, Brenda Andrews
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 5, Pp 521-548 (2024)
Abstract Fluorescence microscopy data describe protein localization patterns at single-cell resolution and have the potential to reveal whole-proteome functional information with remarkable precision. Yet, extracting biologically meaningful represent
Externí odkaz:
https://doaj.org/article/10a4b38bbb1c488aaaefcdc1f2306ba0
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 11, Pp 3969-3976 (2020)
Externí odkaz:
https://doaj.org/article/32e3139a2bdd4ebf9ebf61bffb2eba26
Autor:
Mojca Mattiazzi Usaj, Nil Sahin, Helena Friesen, Carles Pons, Matej Usaj, Myra Paz D Masinas, Ermira Shuteriqi, Aleksei Shkurin, Patrick Aloy, Quaid Morris, Charles Boone, Brenda J Andrews
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 2, Pp 1-27 (2020)
Abstract Our ability to understand the genotype‐to‐phenotype relationship is hindered by the lack of detailed understanding of phenotypes at a single‐cell level. To systematically assess cell‐to‐cell phenotypic variability, we combined auto
Externí odkaz:
https://doaj.org/article/7986b1484d9d4e6cac836c9b612e4d93
Autor:
Brenda J. Andrews, Charles Boone, Quaid Morris, Patrick Aloy, Aleksei Shkurin, Ermira Shuteriqi, Myra Paz David Masinas, Matej Usaj, Carles Pons, Helena Friesen, Nil Sahin, Mojca Mattiazzi Usaj
Our ability to understand the genotype-to-phenotype relationship is hindered by the lack of detailed understanding of phenotypes at a single-cell level. To systematically assess cell-to-cell phenotypic variability, we combined automated yeast genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4505e863eaa31d61b4a9b49192895d13
https://doi.org/10.32920/22149032.v1
https://doi.org/10.32920/22149032.v1
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2381
We describe a protocol for high-content screening in budding yeast that can be used to study genetic interactions from a cell biological perspective. This approach can be used to map genetic interactions by monitoring one or more subcellular fluoresc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83475677c71fbdbce672c366b6dd4f11
https://pubmed.ncbi.nlm.nih.gov/34590270
https://pubmed.ncbi.nlm.nih.gov/34590270
Publikováno v:
Methods Mol Biol
Confocal Microscopy ISBN: 9781071614013
Confocal Microscopy ISBN: 9781071614013
We describe a protocol for live-cell high-throughput (HTP) screening of yeast mutant strains carrying fluorescent protein markers for subcellular compartments of choice using automated confocal microscopy. This procedure, which combines HTP genetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d4a0792a9d3fab9349490b1c31e361
https://pubmed.ncbi.nlm.nih.gov/34028720
https://pubmed.ncbi.nlm.nih.gov/34028720
Publikováno v:
Methods in Molecular Biology ISBN: 9781071617397
We describe a protocol for high-content screening in budding yeast that can be used to study genetic interactions from a cell biological perspective. This approach can be used to map genetic interactions by monitoring one or more subcellular fluoresc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65aec68696ce46a6afe7d1629ff13237
https://doi.org/10.1007/978-1-0716-1740-3_3
https://doi.org/10.1007/978-1-0716-1740-3_3
Autor:
Mojca Mattiazzi Usaj, Brenda J. Andrews, Clarence Hue Lok Yeung, Helena Friesen, Charles Boone
Publikováno v:
Cell Syst
Single-cell image analysis provides a powerful approach for studying cell-to-cell heterogeneity, which is an important attribute of isogenic cell populations, from microbial cultures to individual cells in multicellular organisms. This phenotypic var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991f7afd0284390ccdc7d795dced0a9f
https://pubmed.ncbi.nlm.nih.gov/34139168
https://pubmed.ncbi.nlm.nih.gov/34139168
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 10, Iss 11, Pp 3969-3976 (2020)
G3: Genes, Genomes, Genetics, Vol 10, Iss 11, Pp 3969-3976 (2020)
Advances in genome engineering and high throughput imaging technologies have enabled genome-scale screens of single cells for a variety of phenotypes, including subcellular morphology and protein localization. We constructed TheCellVision.org, a free
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a598ab96d32ee8ef98b754a245385d49
https://pubmed.ncbi.nlm.nih.gov/32934016
https://pubmed.ncbi.nlm.nih.gov/32934016
Autor:
Alan M. Moses, Elena Kuzmin, Michael Pryszlak, Anton Khmelinskii, Matej Usaj, Jolanda van Leeuwen, Alex N. Nguyen Ba, Michael Costanzo, Brenda J. Andrews, Michael Knop, Wen Wang, Oren Kraus, Charles Boone, Brenda Varriano, Elizabeth N. Koch, Benjamin VanderSluis, Chad L. Myers, Mojca Mattiazzi Usaj, Ming Che Hu, Amy Tresenrider
Publikováno v:
Science
The fate of genes after duplication Gene duplication within an organism is a relatively common event during evolution. However, we cannot predict the fate of the duplicated genes: Will they be lost, evolve, or overlap in function within an organismal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee68547824fb20d421995e4fa669822
https://pubmed.ncbi.nlm.nih.gov/32587005
https://pubmed.ncbi.nlm.nih.gov/32587005