Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Mojca Jongen-Lavrencic"'
Autor:
Jacobien R. Hilberink, Isabelle A. van Zeventer, Dana A. Chitu, Thomas Pabst, Saskia K. Klein, Georg Stussi, Laimonas Griskevicius, Peter J. M. Valk, Jacqueline Cloos, Arjan A. van de Loosdrecht, Dimitri Breems, Danielle van Lammeren-Venema, Rinske Boersma, Mojca Jongen-Lavrencic, Martin Fehr, Mels Hoogendoorn, Markus G. Manz, Maaike Söhne, Rien van Marwijk Kooy, Dries Deeren, Marjolein W. M. van der Poel, Marie Cecile Legdeur, Lidwine Tick, Yves Chalandon, Emanuele Ammatuna, Sabine Blum, Bob Löwenberg, Gert J. Ossenkoppele, Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON), Swiss Group for Clinical Cancer Research (SAKK), Gerwin Huls
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Treatment choice according to the individual conditions remains challenging, particularly in older patients with acute myeloid leukemia (AML) and high risk myelodysplastic syndrome (MDS). The impact of performance status, comorbidities, and
Externí odkaz:
https://doaj.org/article/71614de5d82b474e855269ada1ea2dee
Autor:
Anthony Selwyn Stein, Mojca Jongen-Lavrencic, Sylvain Garciaz, Gerwin A Huls, Abhishek Maiti, Nicolas Boissel, Stephane De Botton, Shaun Fleming, C. Michel Zwaan, David C. de Leeuw, Pinkal Desai, Martha Lucia Arellano, David Avigan, Saskia Langemeijer, Kyle Jensen, Timothy Wagenaar, Gu MI, Giovanni Abbadessa, Ashish Bajel
Publikováno v:
HemaSphere, Vol 7, p e66387cd (2023)
Externí odkaz:
https://doaj.org/article/18f46986af184ccba44a04935f01961a
Autor:
Sarah Grasedieck, Christoph Ruess, Kathrin Krowiorz, Susanne Lux, Nicole Pochert, Adrian Schwarzer, Jan-Henning Klusmann, Mojca Jongen-Lavrencic, Tobias Herold, Lars Bullinger, Jonathan R. Pollack, Arefeh Rouhi, Florian Kuchenbauer
Publikováno v:
Haematologica, Vol 105, Iss 9 (2020)
Externí odkaz:
https://doaj.org/article/ad3b271f1fda4e9d87fd4cf93c2d34ec
Autor:
Adrian Schwarzer, Stephan Emmrich, Franziska Schmidt, Dominik Beck, Michelle Ng, Christina Reimer, Felix Ferdinand Adams, Sarah Grasedieck, Damian Witte, Sebastian Käbler, Jason W. H. Wong, Anushi Shah, Yizhou Huang, Razan Jammal, Aliaksandra Maroz, Mojca Jongen-Lavrencic, Axel Schambach, Florian Kuchenbauer, John E. Pimanda, Dirk Reinhardt, Dirk Heckl, Jan-Henning Klusmann
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
While micro-RNAs are known regulators of haematopoiesis and leukemogenesis, the role of long non-coding RNAs is less clear. Here the authors provide a non-coding RNA expression landscape of the human hematopoietic system, highlighting their role in t
Externí odkaz:
https://doaj.org/article/ecded43fcdb64f949d09ac6436b134eb
Autor:
Jeroen Janssen, Bob Löwenberg, Markus Manz, Mario Bargetzi, Bart Biemond, Peter von dem Borne, Dimitri Breems, Rolf Brouwer, Yves Chalandon, Dries Deeren, Anna Efthymiou, Bjørn-Tore Gjertsen, Carlos Graux, Michael Gregor, Dominik Heim, Urs Hess, Mels Hoogendoorn, Aurelie Jaspers, Asiong Jie, Mojca Jongen-Lavrencic, Saskia Klein, Marjolein van der Klift, Jürgen Kuball, Danielle van Lammeren-Venema, Marie-Cecile Legdeur, Arjan van de Loosdrecht, Johan Maertens, Marinus van Marwijk Kooy, Ine Moors, Marten Nijziel, Florence van Obbergh, Margriet Oosterveld, Thomas Pabst, Marjolein van der Poel, Harm Sinnige, Olivier Spertini, Wim Terpstra, Lidwine Tick, Walter van der Velden, Marie-Christiane Vekemans, Edo Vellenga, Okke de Weerdt, Peter Westerweel, Georg Stüssi, Yvette van Norden, Gert Ossenkoppele
Publikováno v:
Cancers, Vol 13, Iss 4, p 672 (2021)
Treatment results of AML in elderly patients are unsatisfactory. We hypothesized that addition of tosedostat, an aminopeptidase inhibitor, to intensive chemotherapy may improve outcome in this population. After establishing a safe dose in a run-in ph
Externí odkaz:
https://doaj.org/article/24fe32a58d25457ab838d412b4becc0b
Autor:
Susanne Hirsch, Tamara J. Blätte, Sarah Grasedieck, Sibylle Cocciardi, Arefeh Rouhi, Mojca Jongen-Lavrencic, Peter Paschka, Jan Krönke, Verena I. Gaidzik, Hartmut Döhner, Richard F. Schlenk, Florian Kuchenbauer, Konstanze Döhner, Anna Dolnik, Lars Bullinger
Publikováno v:
Haematologica, Vol 102, Iss 12 (2017)
In acute myeloid leukemia, there is growing evidence for splicing pattern deregulation, including differential expression of linear splice isoforms of the commonly mutated gene nucleophosmin (NPM1). In this study, we detect circular RNAs of NPM1 and
Externí odkaz:
https://doaj.org/article/b267a0183adc4be8be8c3c386f4f8e44
Autor:
Stephen K. Tahir, Emiliano Calvo, Benedito A. Carneiro, Junichiro Yuda, Aditya Shreenivas, Mojca Jongen-Lavrencic, Eelke Gort, Kenichi Ishizawa, Daniel Morillo, Carla Biesdorf, Morey Smith, Dong Cheng, Monica Motwani, David Sharon, Tamar Uziel, Dimple A. Modi, Fritz G. Buchanan, Susan Morgan-Lappe, Bruno C. Medeiros, Darren C. Phillips
Publikováno v:
Blood, 141(17), 2114-2126. American Society of Hematology
Activation of apoptosis in malignant cells is an established strategy for controlling cancer and is potentially curative. To assess the impact of concurrently inducing the extrinsic and intrinsic apoptosis-signaling pathways in acute myeloid leukemia
Autor:
Tim Grob, Mathijs A. Sanders, Christian M. Vonk, Franҫois G. Kavelaars, Melissa Rijken, Diana W. Hanekamp, Patrycja L. Gradowska, Jacqueline Cloos, Yngvar Fløisand, Marinus van Marwijk Kooy, Markus G. Manz, Gert J. Ossenkoppele, Lidwine W. Tick, Violaine Havelange, Bob Löwenberg, Mojca Jongen-Lavrencic, Peter J.M. Valk
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 41(4):JCO2200715, 756-765. American Society of Clinical Oncology
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 41(4), 756-765. American Society of Clinical Oncology
Grob, T, Sanders, M A, Vonk, C M, Kavelaars, F G, Rijken, M, Hanekamp, D W, Gradowska, P L, Cloos, J, Fløisand, Y, van Marwijk Kooy, M, Manz, M G, Ossenkoppele, G J, Tick, L W, Havelange, V, Löwenberg, B, Jongen-Lavrencic, M & Valk, P J M 2023, ' Prognostic Value of FLT3-Internal Tandem Duplication Residual Disease in Acute Myeloid Leukemia ', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 41, no. 4, pp. 756-765 . https://doi.org/10.1200/JCO.22.00715, https://doi.org/10.1200/JCO.22.00715
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 41(4), 756-765. American Society of Clinical Oncology
Grob, T, Sanders, M A, Vonk, C M, Kavelaars, F G, Rijken, M, Hanekamp, D W, Gradowska, P L, Cloos, J, Fløisand, Y, van Marwijk Kooy, M, Manz, M G, Ossenkoppele, G J, Tick, L W, Havelange, V, Löwenberg, B, Jongen-Lavrencic, M & Valk, P J M 2023, ' Prognostic Value of FLT3-Internal Tandem Duplication Residual Disease in Acute Myeloid Leukemia ', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 41, no. 4, pp. 756-765 . https://doi.org/10.1200/JCO.22.00715, https://doi.org/10.1200/JCO.22.00715
PURPOSE The applicability of FLT3-internal tandem duplications ( FLT3-ITD) for assessing measurable residual disease (MRD) in acute myeloid leukemia (AML) in complete remission (CR) has been hampered by patient-specific duplications and potential ins
Autor:
Armin Zebisch, Heinz Sill, Jakob Troppmair, Albert Wölfler, Franz Quehenberger, Mojca Jongen-Lavrencic, Katarzyna Nowek, Marcel Scheideler, Martin Pichler, Rotraud Wieser, Erika Nussbaumer, Tobias Furlan, Till Seime, Veronica Caraffini, Maja Kim Kuepper, Olivia Geiger, Stefan Hatzl
RKIP knockdown in U937 does not affect NF-κB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28dfbf4c715c252b01ed1537dd46b666
https://doi.org/10.1158/0008-5472.22411196
https://doi.org/10.1158/0008-5472.22411196
Autor:
Armin Zebisch, Heinz Sill, Jakob Troppmair, Albert Wölfler, Franz Quehenberger, Mojca Jongen-Lavrencic, Katarzyna Nowek, Marcel Scheideler, Martin Pichler, Rotraud Wieser, Erika Nussbaumer, Tobias Furlan, Till Seime, Veronica Caraffini, Maja Kim Kuepper, Olivia Geiger, Stefan Hatzl
Datasets downloaded from TCGA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a89f91f7c4217c4474987ce6b51bce3
https://doi.org/10.1158/0008-5472.22411184
https://doi.org/10.1158/0008-5472.22411184